2019
DOI: 10.3390/molecules24244594
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Application of Deep Eutectic Solvents in Food Analysis: A Review

Abstract: Deep eutectic solvents (DESs) have emerged recently as new and green solvents. DESs can be used for extraction and separation of both inorganic metallic components and organic compounds such as phenolic compounds, flavonoids, sugars, and aromatic amines from food samples. DESs possess a tunable property simply by adjusting the ratio of hydrogen bond acceptors to the hydrogen bond donors. As a green extraction medium, DESs have various applications in the pretreatment process and improve the efficiency of diffe… Show more

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Cited by 74 publications
(41 citation statements)
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“…In combination with several innovative extraction techniques, these eco-friendly solvents have been recently used to extract, separate and pre-concentrate bioactive compounds from natural sources, namely polyphenols (e.g., phenolic acids and flavonoids), alkaloids, cannabinoids, ginkgolides, etc. [ 17 , 18 ]. Besides NADES composition and molecular structure, other factors like molecular ratio, water content, temperature, extraction time, solvent/sample ratio, and pH play an important role in the efficiency and yield of the extraction process [ 15 ].…”
Section: Introductionmentioning
confidence: 99%
“…In combination with several innovative extraction techniques, these eco-friendly solvents have been recently used to extract, separate and pre-concentrate bioactive compounds from natural sources, namely polyphenols (e.g., phenolic acids and flavonoids), alkaloids, cannabinoids, ginkgolides, etc. [ 17 , 18 ]. Besides NADES composition and molecular structure, other factors like molecular ratio, water content, temperature, extraction time, solvent/sample ratio, and pH play an important role in the efficiency and yield of the extraction process [ 15 ].…”
Section: Introductionmentioning
confidence: 99%
“…Ma et al [ 70 ] investigated the effect of water on CO 2 solubility using glycerol-based DESs. Most of the glycerol-based DESs have high viscosity; however, for some DESs, viscosity changes drastically when a small amount of water is added [ 71 ]. For instance, the viscosity of BTMA/gly (1:2) DES was reduced from 716 to 20 mPa·s after adding a small quantity of water (0.11 mole fraction).…”
Section: Co 2 Capturementioning
confidence: 99%
“…Two final aspects need to be consider when employing NADES as cosolvents in redox biocatalyzed processes. First, NADES are good solvents with several applications in extraction processes [ 98 , 99 , 100 ], so sometimes the recovery of the final product from the reaction medium can present some issues, a question to be taken into account for process designing. Finally, NADES can be recycled from the reaction media and used for several times, another aspect to consider.…”
Section: Conclusion and Future Perspectivesmentioning
confidence: 99%