Artificial pleural effusion and/or ascites for percutaneous radiofrequency ablation of hepatocellular carcinoma

Abstract

Radiofrequency ablation (RFA) with artificial pleural effusion and/or artificial ascites has recently been recognized as a useful device for the treatment of tumors located on the liver surface and in the hepatic dome. Sixty patients (including 32 naive patients) with hepatocellular carcinoma (HCC) underwent RFA with artificial pleural effusion and/or ascites. We decided the precise indication for the use of artificial infusion according to the location of tumor. The total local recurrence rates at 1 and 2 years were 4% and 22%, respectively. The estimated survival rates of 32 naive patients at 1 and 3 years were 90% and 78%, respectively. The local recurrence rates of a tumor size of <3 cm and > = 3 cm at 2 years were 22% and 17%, respectively.

Outcomes of laparoscopic hepatic resection versus percutaneous radiofrequency ablation for hepatocellular carcinoma located at the liver surface: A case-control study with propensity score matching

“…In this study, the local recurrence rate for surface HCC was 31% (30% following PSM) with a cumulative local recurrence rate at 3 years of 38.6% (38.6% following PSM) in the P‐RFA group. This is in agreement with previous reports because surface HCC as well as large tumor size, a serum concentration of DCP of 200 mAU/mL, an ablation margin of 5 mm and the presence of contiguous vessels have been reported to be risk factors for local recurrence following RFA . In particular, Hori, et al.…”

“…b). When a residual tumor was detected, additional therapy was performed until complete necrosis was confirmed . All patients in this study were discharged from the hospital after the certification of complete ablation on imaging.…”

“…Artificial pleural effusion was indicated for some cases with tumors located on the dorsal side of the liver surface in the right lobe, and artificial ascites was indicated for: (i) tumors located on the ventral side of the liver surface in the right lobe; (ii) tumors that could not be completely visualized on US but were located near the liver surface in the right lobe; and (iii) tumors on the liver surface and attached to adjacent organs. We used 5% glucose (Otsuka Pharmaceutical, Tokyo , Japan ) as artificial pleural effusion and ascites . A total of 37 (71%) of the 52 patients received P‐RFA after inducing artificial pleural effusion and/or ascites.…”

A Case of Diaphragmatic Hernia Induced by Radiofrequency Ablation for Hepatocellular Carcinoma

“…18 One study suggested that the placement of artificial devices should differ depending on the location of the tumor: for artificial pleural effusion, dorsal aspect of the liver surface in the right lobe, and for artificial ascites; 1) ventral aspect of the liver surface in the right lobe, 2) tumors located on the liver surface and attached to surrounding organs. 19 In our case, because the lesion was located on the ventral side of the liver surface, we assumed that he should be treated by using artificial ascites to decrease the thermal damage at that time.…”

MR-guided Percutaneous Biopsy of Focal Hepatic Dome Lesions with Free-hand Combined with MR Fluoroscopy Using 1.0-T Open High-field Scanner

“…There are several techniques, including the use of an artificial fluid (artificial pleural effusion or artificial ascites) or air, to overcome these limitations (6). However, all these methods ask for the operators having a certain degree of surgical skill and need a second surgical trauma, not to mention adding the procedure time (7). In recent years, magnetic resonance imaging (MRI)-guided percutaneous biopsy has been successfully used in different anatomical organs (8), such as the lungs, brain and prostate.…”