2018
DOI: 10.1097/aln.0000000000001984
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Artificial Intelligence for Everyone

Abstract: "…machine learning to model the interaction of remifentanil and propofol on processed electroencephalogram…. Is this the end of clinical pharmacology?"

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Cited by 38 publications
(19 citation statements)
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“…As Gambus and Shafer 99 point out in their recent editorial on artificial intelligence, humans have the ability to extrapolate from the known to the unknown based on a more complete understanding of scientific phenomena, but artificial intelligence can only draw conclusions from the data it has seen and analyzed. 99 As more and more elements of clinical practice become digitized and accumulated into databases, we may one day see the development of artificial intelligence systems that have a more complete understanding of clinical phenomena and thus greater potential to deliver elements of anesthesia care autonomously.…”
Section: Artificial Intelligence In Anesthesiologymentioning
confidence: 99%
“…As Gambus and Shafer 99 point out in their recent editorial on artificial intelligence, humans have the ability to extrapolate from the known to the unknown based on a more complete understanding of scientific phenomena, but artificial intelligence can only draw conclusions from the data it has seen and analyzed. 99 As more and more elements of clinical practice become digitized and accumulated into databases, we may one day see the development of artificial intelligence systems that have a more complete understanding of clinical phenomena and thus greater potential to deliver elements of anesthesia care autonomously.…”
Section: Artificial Intelligence In Anesthesiologymentioning
confidence: 99%
“…26 However, there are areas of concern for the use of ML in anesthesiology and perioperative medicine due to its potential impact on patient safety and reliability, removing the autonomy of clinicians, and negative impact on clinical decision heuristics. [27][28][29][30][31] 1) The very fact that the data used to build the models underlying the mythical ML applications are the drivers of ML read-outs tells us the varying degree of patient safety and reliability of ML. 27 While models are now being refined with increased data points, we cannot deny the future where we interact with these algorithms.…”
Section: Technology Innovations In Anesthesiologymentioning
confidence: 99%
“…In post hoc analysis, the classical pharmacokinetic/ pharmacodynamic models were able to predict the BIS value with a root-mean-square error of 15 over all phases of the anesthetic. Despite being naive to all existing theory, the neural network comfortably outperformed the best current models with an root-mean-square error of 9-a remarkable victory for modern artificial intelligence over existing classical pharmacokinetic/pharmacodynamic expert systems 47 that might lead us to question the ongoing utility of classical response surface models. 48…”
Section: Artificial Intelligence and Machine Learningmentioning
confidence: 99%