Artificial Intelligence and Primary Care Research: A Scoping Review

Kueper, Jacqueline K; Terry, Amanda; Zwarenstein, Merrick; Lizotte, Daniel J.

doi:10.1370/afm.2518

Cited by 76 publications

(96 citation statements)

References 55 publications

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“…Worldwide, there is a great deal of interest in AI techniques and their potential in medicine, not least in the United Kingdom where politicians and NHS leaders have publicly prioritized the incorporation of AI into clinical settings. Our findings support those of Kueper et al [ 17 ], namely, that although some AI techniques have good initial validation reports, they have not yet been through the steps for full application in clinical practice. Validation using independent data is preferable to splitting a single data set [ 185 ] and could be the next step in the development of many AI techniques identified in this review.…”

Section: Discussionsupporting

confidence: 91%

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Artificial Intelligence Techniques That May Be Applied to Primary Care Data to Facilitate Earlier Diagnosis of Cancer: Systematic Review

Jones¹,

Calanzani²,

Saji³

et al. 2021

J Med Internet Res

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Background More than 17 million people worldwide, including 360,000 people in the United Kingdom, were diagnosed with cancer in 2018. Cancer prognosis and disease burden are highly dependent on the disease stage at diagnosis. Most people diagnosed with cancer first present in primary care settings, where improved assessment of the (often vague) presenting symptoms of cancer could lead to earlier detection and improved outcomes for patients. There is accumulating evidence that artificial intelligence (AI) can assist clinicians in making better clinical decisions in some areas of health care. Objective This study aimed to systematically review AI techniques that may facilitate earlier diagnosis of cancer and could be applied to primary care electronic health record (EHR) data. The quality of the evidence, the phase of development the AI techniques have reached, the gaps that exist in the evidence, and the potential for use in primary care were evaluated. Methods We searched MEDLINE, Embase, SCOPUS, and Web of Science databases from January 01, 2000, to June 11, 2019, and included all studies providing evidence for the accuracy or effectiveness of applying AI techniques for the early detection of cancer, which may be applicable to primary care EHRs. We included all study designs in all settings and languages. These searches were extended through a scoping review of AI-based commercial technologies. The main outcomes assessed were measures of diagnostic accuracy for cancer. Results We identified 10,456 studies; 16 studies met the inclusion criteria, representing the data of 3,862,910 patients. A total of 13 studies described the initial development and testing of AI algorithms, and 3 studies described the validation of an AI algorithm in independent data sets. One study was based on prospectively collected data; only 3 studies were based on primary care data. We found no data on implementation barriers or cost-effectiveness. Risk of bias assessment highlighted a wide range of study quality. The additional scoping review of commercial AI technologies identified 21 technologies, only 1 meeting our inclusion criteria. Meta-analysis was not undertaken because of the heterogeneity of AI modalities, data set characteristics, and outcome measures. Conclusions AI techniques have been applied to EHR-type data to facilitate early diagnosis of cancer, but their use in primary care settings is still at an early stage of maturity. Further evidence is needed on their performance using primary care data, implementation barriers, and cost-effectiveness before widespread adoption into routine primary care clinical practice can be recommended.

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Section: Discussionsupporting

confidence: 91%

“…Few studies of AI-based techniques for the early detection of cancer have been undertaken in primary care settings [ 17 ]. Therefore, the aim of this systematic review is to identify AI techniques that facilitate the early detection of cancer and could be applied to primary care EHR data.…”

Section: Introductionmentioning

confidence: 99%

Artificial Intelligence Techniques That May Be Applied to Primary Care Data to Facilitate Earlier Diagnosis of Cancer: Systematic Review

Jones¹,

Calanzani²,

Saji³

et al. 2021

J Med Internet Res

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“…Confirming this, a review on artificial intelligence (AI) in primary care indicated that only 14% of published studies reporting development of AI diagnostic or treatment support algorithms had authors who were employed in primary care [ 34 ].…”

Section: Introductionmentioning

confidence: 99%

Barriers and facilitators to the adoption of electronic clinical decision support systems: a qualitative interview study with UK general practitioners

Ford

Edelman

Somers

et al. 2021

BMC Med Inform Decis Mak

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Background Well-established electronic data capture in UK general practice means that algorithms, developed on patient data, can be used for automated clinical decision support systems (CDSSs). These can predict patient risk, help with prescribing safety, improve diagnosis and prompt clinicians to record extra data. However, there is persistent evidence of low uptake of CDSSs in the clinic. We interviewed UK General Practitioners (GPs) to understand what features of CDSSs, and the contexts of their use, facilitate or present barriers to their use. Methods We interviewed 11 practicing GPs in London and South England using a semi-structured interview schedule and discussed a hypothetical CDSS that could detect early signs of dementia. We applied thematic analysis to the anonymised interview transcripts. Results We identified three overarching themes: trust in individual CDSSs; usability of individual CDSSs; and usability of CDSSs in the broader practice context, to which nine subthemes contributed. Trust was affected by CDSS provenance, perceived threat to autonomy and clear management guidance. Usability was influenced by sensitivity to the patient context, CDSS flexibility, ease of control, and non-intrusiveness. CDSSs were more likely to be used by GPs if they did not contribute to alert proliferation and subsequent fatigue, or if GPs were provided with training in their use. Conclusions Building on these findings we make a number of recommendations for CDSS developers to consider when bringing a new CDSS into GP patient records systems. These include co-producing CDSS with GPs to improve fit within clinic workflow and wider practice systems, ensuring a high level of accuracy and a clear clinical pathway, and providing CDSS training for practice staff. These recommendations may reduce the proliferation of unhelpful alerts that can result in important decision-support being ignored.

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“…Moreover, application of AI appeared to enable more personalized care pathways based on personal health profiles [18]. The COVID-19 pandemic requires existing health care models to have better integration, delivery, and distribution capabilities, and thus, new requirements for AI in eHealth have been put forward [18,28,29]. Thus far, the main fields that AI technology has been applied to during the pandemic is early detection and diagnosis of infections, personal contact tracking, case and mortality prediction, drug and vaccine development, reducing the workload of medical staff, and other aspects of controlling and managing the spread of the virus [23].…”

Section: Potential Of Artificial Intelligencementioning

confidence: 99%

A Patient Journey Map to Improve the Home Isolation Experience of Persons With Mild COVID-19: Design Research for Service Touchpoints of Artificial Intelligence in eHealth

He¹,

Du²,

Simonse³

2021

JMIR Med Inform

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Background In the context of the COVID-19 outbreak, 80% of the persons who are infected have mild symptoms and are required to self-recover at home. They have a strong demand for remote health care that, despite the great potential of artificial intelligence (AI), is not met by the current services of eHealth. Understanding the real needs of these persons is lacking. Objective The aim of this paper is to contribute a fine-grained understanding of the home isolation experience of persons with mild COVID-19 symptoms to enhance AI in eHealth services. Methods A design research method with a qualitative approach was used to map the patient journey. Data on the home isolation experiences of persons with mild COVID-19 symptoms was collected from the top-viewed personal video stories on YouTube and their comment threads. For the analysis, this data was transcribed, coded, and mapped into the patient journey map. Results The key findings on the home isolation experience of persons with mild COVID-19 symptoms concerned (1) an awareness period before testing positive, (2) less typical and more personal symptoms, (3) a negative mood experience curve, (5) inadequate home health care service support for patients, and (6) benefits and drawbacks of social media support. Conclusions The design of the patient journey map and underlying insights on the home isolation experience of persons with mild COVID-19 symptoms serves health and information technology professionals in more effectively applying AI technology into eHealth services, for which three main service concepts are proposed: (1) trustworthy public health information to relieve stress, (2) personal COVID-19 health monitoring, and (3) community support.

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Artificial Intelligence and Primary Care Research: A Scoping Review

Cited by 76 publications

References 55 publications

Artificial Intelligence Techniques That May Be Applied to Primary Care Data to Facilitate Earlier Diagnosis of Cancer: Systematic Review

Artificial Intelligence Techniques That May Be Applied to Primary Care Data to Facilitate Earlier Diagnosis of Cancer: Systematic Review

Barriers and facilitators to the adoption of electronic clinical decision support systems: a qualitative interview study with UK general practitioners

A Patient Journey Map to Improve the Home Isolation Experience of Persons With Mild COVID-19: Design Research for Service Touchpoints of Artificial Intelligence in eHealth

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