Arterial Surgery and Angioplasty in Patients Under 40 Years of Age: A Retrospective Study

Abstract

Seventy-nine patients (35 male, 44 female) under 40 years of age who had undergone arterial surgery or percutaneous transluminal angioplasty (PTA), except for trauma and thromboembolism, were retrospectively analyzed for risk factors, types of intervention and outcome. Of those patients with renovascular disease (n = 45), fibromuscular dysplasia dominated (71%). Thirty-seven patients had primary reconstruction, 7 had percutaneous transluminal renal angioplasty (PTRA) and 1 had a nephrectomy. There was no postoperative mortality within 30 days. One patient died, 3 had nephrectomies later, and 1 had a pole resection during follow-up. At the end of the follow-up, 38 (84%) patients, including 1 with primary nephrectomy, were cured or improved in regard to hypertension, and 7 (16%) did not improve. Of patients with peripheral vascular disease (n = 34), atherosclerosis dominated. There was 1 postoperative death and 1 amputation within 30 days. Because of progressive disease there were 2 late deaths, 3 amputations, 3 repeat procedures, 4 other vascular reconstructions and three cardiocerebrovascular events. With an active and aggressive approach in patients with renovascular disease, the outcome is good. Peripheral arterial surgery in patients under 40 years has a less favorable outcome, probably due to more generalized disease.