2008
DOI: 10.1097/aco.0b013e3282f2bb79
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Arterial oxygenation and one-lung anesthesia

Abstract: The effects of anesthesia techniques on oxygen consumption, cardiac output and therefore mixed venous oxygenation can significantly affect arterial oxygenation during one-lung anesthesia. While pursuing increases in cardiac output may, under limited circumstances, benefit arterial oxygenation during one-lung ventilation, this approach is not a panacea and does not obviate the necessity to optimize dependent lung volume.

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Cited by 21 publications
(14 citation statements)
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“…Lower peripheral resistance was noted in the PHC group, and non-oxygenated blood shunting was comparable in both groups. The obtained results confirm the vasoconstrictive effect of hypercapnia on pulmonary circulation, which results in the intensification of HPV [30]. Adrenergic activity, resulting from respiratory acidosis, causes an increase in the cardiac index and mean arterial pressure.…”
Section: Kardiochirurgia I Torakochirurgia Polska 2013; 10 (4)supporting
confidence: 71%
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“…Lower peripheral resistance was noted in the PHC group, and non-oxygenated blood shunting was comparable in both groups. The obtained results confirm the vasoconstrictive effect of hypercapnia on pulmonary circulation, which results in the intensification of HPV [30]. Adrenergic activity, resulting from respiratory acidosis, causes an increase in the cardiac index and mean arterial pressure.…”
Section: Kardiochirurgia I Torakochirurgia Polska 2013; 10 (4)supporting
confidence: 71%
“…While using HFJV, the efficient elimination of carbon dioxide is conditioned on respiratory cycle frequency, drive pressure (DP), and the ratio between inhalation and exhalation times [30]. High breathing frequency, short inhalation time, and low drive pressures contribute to carbon dioxide retention.…”
Section: Kardiochirurgia I Torakochirurgia Polska 2013; 10 (4)mentioning
confidence: 99%
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“…Sie kann die Perfusion auf bis zu 50% reduzieren, sodass die Shunt-Fraktion bei ELV auf ca. 20-30% des HZV kalkuliert werden muss [7,8,9,10,11] [12], sodass die arterielle Oxygenierung während ELV mit vom HZV abhän-gig ist. So zeigten klinische Studien, dass eine Erhöhung des HZV um 25%, die von einem gemischtvenösen Sättigungsanstieg von 60 auf 74,6% begleitet war, zu einer signifikanten Verbesserung der arteriellen Oxygenierung unter ELV führte [13,14].…”
Section: Hypoxische Pulmonale Vasokonstriktionunclassified
“…1. The unfavorable ratios of local ventilation to perfusion (V/Q) created by both the total collapse of the operated/non-ventilated lung and the different states of aeration and perfusion in the ventilated lung lead to inefficiencies of gas exchange, witnessed clinically as hypoxemia and hypercapnia of different degrees [14,15].…”
Section: Gas Exchange During Thoracic Surgeries With Onelung Ventilationmentioning
confidence: 99%