Arterial blood pressure and serum lipids in a population of children and adolescents from Southern Italy: The Calabrian Sierras Community Study (CSCS)

Martino, Francesco De; Puddu, Paolo Emilio; Pannarale, Giuseppe; Colantoni, Chiara; Zanoni, Cristina; Martino, Eliana; Barillà, Francesco

doi:10.1016/j.ijcard.2012.11.045

Cited by 18 publications

(25 citation statements)

References 15 publications

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“…Average values for HDL cholesterol (54 ± 15 mg/dl), triglycerides (61 ± 29 mg/dl), blood glucose (78 ± 10 mg/dl), systolic BP (101 ± 11 mm Hg), WC (66 ± 10 cm) and WC/height ratio (0.46 ± 0.006) were previously reported [9]. Average values for diastolic BP were 62 ± 10 mm Hg whereas average triglycerides/HDL cholesterol ratio was 1.31 ± 0.99.…”

Section: Resultsmentioning

confidence: 59%

“…The conduct of the CSCS was previously reported in detail [9]. Briefly, CSCS was performed on the entire population of children and adolescents from primary and secondary schools in 14 towns of the Vibo Valentia (Calabria, Southern Italy) district.…”

Section: Methodsmentioning

confidence: 99%

“…Local school authorities contacted all resident 2594 children and adolescents although we concentrated only on those aged 6-14. The study was performed in accordance with ethics and Italian laws on medical practice and was approved by the independent Ethical Committee [9]. Every child received a family medical history questionnaire at school that was filled up by the parents at home.…”

Section: Methodsmentioning

confidence: 99%

“…The purpose of the present study was fourfold, at: a) using all 5 MS components in children and adolescents aged 6-14 years using the Calabrian Sierras Community Study (CSCS), a residential cohort from Southern Italy [9]; b) reporting gender-and age-quantile distributions of these characteristics and of derived variables (WC/height and triglycerides/HDL cholesterol ratios); c) describing percentile distributions of all 5 characteristics concentrating on the ≥ 90th percentile for WC, triglycerides, blood glucose, and BP (systolic or diastolic) and ≤10th for HDL cholesterol [7]; and d) assessing MS prevalence in CSCS, based on abnormal percentile distributions of 3 out of 5 characteristics.…”

Section: Introductionmentioning

confidence: 99%

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Metabolic syndrome among children and adolescents from Southern Italy: Contribution from the Calabrian Sierras Community Study (CSCS)

Martino¹,

Puddu²,

Pannarale³

et al. 2014

International Journal of Cardiology

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Section: Resultsmentioning

confidence: 59%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Metabolic syndrome among children and adolescents from Southern Italy: Contribution from the Calabrian Sierras Community Study (CSCS)

Martino¹,

Puddu²,

Pannarale³

et al. 2014

International Journal of Cardiology

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“…It remains for further investigation to assess whether also in Southern European Countries, practicing Mediterranean diet as a normal habit, DF may indeed contribute to modify the relatively low proportion of hyperlipemia observed in our population [85]. Clearly, adequately powered and controlled trials are needed.…”

Section: Discussionmentioning

confidence: 95%

Dietary Fibers and Nutraceuticals for Primary Cardiovascular Prevention in Children and Adolescents: A Critical Review

Martino¹,

Puddu²,

Pannarale³

et al. 2013

FNS

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The roles of dietary fibers and nutraceuticals for primary prevention of cardiovascular disease from childhood are reviewed. Nutrition as an epigenetic modifier and the roles of endothelium, risk factors, epidemiological evidence and Mediterranean diet are critically analysed. Overfeeding in childhood can lead to the development of obesity and/or atherosclerosis in adult life. In particular, a high intake of nutrients affects the in utero programming with the adverse consequences of insulin resistance an endothelial dysfunction that lead to early atherosclerosis. Dietary fibers have important health benefits in childhood and research suggests that they may prevent obesity and lower blood cholesterol levels with a favourable impact on the risk of future cardiovascular disease incidence. However, it is for further studies to assess whether also in Southern European Countries, practicing Mediterranean diet as a normal habit, dietary fibers may contribute to modify the relatively low proportion of hyperlipemia observed in our population.

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Associations between metabolic syndrome components and markers of inflammation in Welsh school children

et al. 2017

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We investigated the multivariate dimensionality and strength of the relationship between metabolic syndrome (MetS) and inflammation in children. Caucasian school children (N = 229; 12–14 years) from Wales were tested on several health indicators including measures of body composition, inflammation, fasting glucose regulation, blood pressure, and lipids. The multivariate association between MetS and inflammation was investigated via canonical correlation analysis. Data were corrected for non-normality by log transformation, and sex-specific z-scores computed for variables where there was a significant sex difference. Structure r’s were interpreted to determine the dimensions of MetS and inflammation responsible for significant canonical variates. The overall multivariate association between MetS and inflammation was significant (Wilks’ Lambda = 0.54, p < 0.001). The relationship was explained primarily by the waist circumference dimension of MetS (CC = 0.87) and inflammatory markers of fibrinogen (CC = 0.52) and C-reactive protein (CC = 0.50). The pattern of results was similar regardless of whether variables were adjusted for sex differences. Conclusion: Central adiposity is the strongest predictor of the inflammatory aspect of cardiovascular disease risk in Caucasian adolescents. Future research into MetS and cardiometabolic risk should consider multivariate statistical approaches, in order to identify the separate contributions of each dimension in interrelationships and to identify which dimensions are influenced by preventive interventions. What is Known: • Metabolic syndrome (MetS) is associated with increased risk of cardiovascular disease (CVD) and type 2 diabetes. Markers of inflammation are also potential predictors of later development of CVD and type 2 diabetes. • The contribution of individual markers in interrelationships between MetS and inflammation is unknown. What is New: • We uniquely demonstrate that within a multivariate model, waist circumference is the primary link between MetS variables and markers of inflammation in children. • Waist circumference may therefore be a useful population-level screening tool to identify future risk of CVD.

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Arterial blood pressure and serum lipids in a population of children and adolescents from Southern Italy: The Calabrian Sierras Community Study (CSCS)

Cited by 18 publications

References 15 publications

Metabolic syndrome among children and adolescents from Southern Italy: Contribution from the Calabrian Sierras Community Study (CSCS)

Metabolic syndrome among children and adolescents from Southern Italy: Contribution from the Calabrian Sierras Community Study (CSCS)

Dietary Fibers and Nutraceuticals for Primary Cardiovascular Prevention in Children and Adolescents: A Critical Review

Associations between metabolic syndrome components and markers of inflammation in Welsh school children

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