2020
DOI: 10.1016/j.jep.2020.113191
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Artemisia annua and Artemisia afra extracts exhibit strong bactericidal activity against Mycobacterium tuberculosis

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Cited by 52 publications
(49 citation statements)
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“…Following a 30 min room-temperature incubation, absorbance was measured at 415 nm, using quercetin in a standard curve with total flavonoids expressed in quercetin units. Another aliquot of each extract in each solvent was analyzed for ART via gas chromatography-mass spectroscopy as detailed by Martini et al [ 37 ]. Using these ART concentrations, the remaining bulk of the extract was dried and resuspended to 20 mM ART in DMSO.…”
Section: Methodsmentioning
confidence: 99%
“…Following a 30 min room-temperature incubation, absorbance was measured at 415 nm, using quercetin in a standard curve with total flavonoids expressed in quercetin units. Another aliquot of each extract in each solvent was analyzed for ART via gas chromatography-mass spectroscopy as detailed by Martini et al [ 37 ]. Using these ART concentrations, the remaining bulk of the extract was dried and resuspended to 20 mM ART in DMSO.…”
Section: Methodsmentioning
confidence: 99%
“…Sterile infusion was aliquoted into 1.5 mL tubes and stored at -80°C. Artemisinin content of the filtered infusions was determined by gas chromatography mass spectroscopy (GCMS) as detailed in Martini et al 2020(Martini et al, 2020. SAM A. annua and SEN A. afra tea infusions contained 283 and 0.69 µM artemisinin, respectively; A. afra PAR and LUX contained no detectable artemisinin.…”
Section: Plant Materials and Its Preparation For Testingmentioning
confidence: 99%
“…Artemisinin and its derivatives are not only effective against malaria, but also against various types of cancers and tumors (Efferth 2017), some viruses (Efferth et al 2008;Efferth 2018) including SARS-CoV-2 (Nair Communicated by Gerhard Leubner. et al 2021), tuberculosis (Martini et al 2020;Zheng et al 2017), and many other parasites including Schistosoma sp. (Munyangi et al 2018), Leishmania sp.…”
Section: Introductionmentioning
confidence: 99%