Arsenic induced toxicity and histopathological changes in gill and liver tissue of freshwater fish, tilapia (Oreochromis mossambicus)

Ahmed, Md. Kawser; Habibullah-Al-Mamun, Md.; Parvin, Elora; Akter, Mosammat Salma; Khan, Mohammad Rezwan

doi:10.1016/j.etp.2013.01.003

Cited by 117 publications

(45 citation statements)

References 25 publications

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“…The observed pathological changes after butachlor treatment in the gills of rainbow trout are in agreement with reports in other fish species treated with different pollutants (Cengiz and Unlu 2003;Altinok and Capkin 2007;Velmurugan et al 2009;Ahmed et al 2013). This is perhaps because of the direct contact of gills with the toxin.…”

Section: Discussionsupporting

confidence: 80%

Histopathological and haematological response of male rainbow trout (Oncorhynchus mykiss) subjected to butachlor

Ahmadivand¹,

Farahmand²,

Mirvaghefi³

et al. 2014

Vet. Med. - Czech

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This study was aimed at assessing the histopathological and haematological effects of a widely used herbicide on rice paddy fields, i.e. butachlor, on rainbow trout. Fish were exposed to butachlor at a concentration of 0.39 mg/l, for a period of 10 days. Haematologically, fish showed a significant decrease in erythrocyte count, haemoglobin, white blood cells and lymphocytes and a significant increase in neutrophils compared to controls (P < 0.05). Histopathological observations of prepared sections of the treatment group also revealed pathological lesions of varying severity in studied organs, including liver (hyperaemia and haemorrhage, bile duct hyperplasia, dilated sinuses, interstitial oedema, monocellular necrosis, nuclear degeneration and hypertrophy in hepatocytes), gills (hyperplasia and hyperplasia of lamellar epithelium, fusion of lamellae, rod-like structures of secondary gill lamellae, cystic-like lesions) and kidneys (vacuolar degeneration of tubular epithelium, desquamation of epithelium and necrosis of tubular epithelium). It is concluded that butachlor caused changes in certain haematological parameters and histopathologically, exerted destructive effects on the gills, liver and kidneys of rainbow trout.

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Section: Discussionsupporting

confidence: 80%

Histopathological and haematological response of male rainbow trout (Oncorhynchus mykiss) subjected to butachlor

Ahmadivand¹,

Farahmand²,

Mirvaghefi³

et al. 2014

Vet. Med. - Czech

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“…Most of the pathologies found in the liver of Chasicó Lake fishes were reported by other authors (Shah et al 2009, Višnjić-Jeftić et al 2010, Jarić et al 2011, however, peliosis areas were not found. In contrast, Ahmed et al (2013) reported cellular rupture in hepatocytes of Oreochromis mossambicus that occurs either directly by denaturation of volume-regulating ATPases or indirectly by disruption of the cellular energy transfer processes required for ionic regulation. The gills are important organs with multiple functions, including gas exchange, osmotic pressure regulation, acid-base balance, ion transport and excretion of nitrogenous waste, which are closely related to chloride cells of epithelial cells in gills (Mallatt 1985).…”

Section: Fig 3 (A) Liver Of Control Fish (10×) (B) Hemosiderin In mentioning

confidence: 83%

HISTOPATHOLOGICAL CHANGES IN LIVER AND GILLS OF Odontesthes bonariensis INHABITING A LAKE WITH HIGH CONCENTRATIONS OF ARSENIC AND FLUORIDE (CHASICÓ LAKE, BUENOS AIRES PROVINCE)

Puntoriero¹,

Cirelli²,

Volpedo³

2018

Rev. Int. Contam. Ambie.

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Water bodies in the Chaco-Pampean plain contain arsenic (As) and fluoride (F -) occurring naturally. Chasicó Lake, located in the southwest of Buenos Aires Province, has high concentrations of both elements (As, 0.05-0.41 mg/L; F -, 6.74-8.54 mg/L). Fish can be considered as indicators of environmental pollution. The aim of this study was to analyze whether the presence of high concentrations of As and F -found in the liver and gills of Odonthestes bonariensis could be associated to histological changes found in these tissues. Fish were sampled from different locations of the lake. Tissue samples (liver and gills) were subdivided and subjected to an acid digestion to determine As and to an alkaline digestion to determine F -. Morphological changes were assessed using routine histological techniques. As concentrations in the liver were higher than in the gills, while the gills showed higher F -concentrations. The histological examination of the liver and gills showed alterations that could correspond to the effects of the high As and F -concentrations found in these tissues. The toxicity of these elements is due to oxidative stress. Silverside is one commercially relevant fish in Buenos Aires and a key species in the food chain in the region. Therefore, further histopathological studies are relevant to guarantee this fish's health and safety for human consumption.Palabras clave: histopatología, elementos traza, pejerrey, Argentina RESUMEN Los cuerpos de agua de la llanura Chaco-Pampeana contienen arsénico (As) y fluoruro (F -) cuyo origen es natural. El Lago Chasicó, ubicado en el sudoeste bonaerense, presenta elevadas concentraciones de ambos elementos (As: 0.05-0.41 mg/L; F -: 6.74-8.54 mg/L). Los peces pueden considerarse como indicadores de contaminación ambiental. El objetivo de este estudio fue analizar si la presencia de altas concentraciones de As y F -halladas en hígado y branquias de Odonthestes bonariensis pudiera estar asociada con los cambios histológicos encontrados en estos tejidos. Los peces fueron colectados en diferentes localidades del lago. Se subdividieron muestras de tejidos (hígado y branquias) y se sometieron a una digestión ácida para determinar As y a una digestión Rev. Int. Contam. Ambie. 34 (1) 69-77, 2018 DOI: 10.20937/RICA.2018 M.L. Puntoriero et al. 70alcalina para determinar F -. Los cambios morfológicos se determinaron mediante técnicas histológicas de rutina. En hígado se hallaron concentraciones de As más altas que en branquias, mientras que las branquias mostraron concentraciones de F -más elevadas. El examen histológico del hígado y las branquias mostró alteraciones que podrían corresponder a los efectos de las altas concentraciones de As y F -halladas en esos tejidos. La toxicidad de estos elementos se debe al estrés oxidativo. El pejerrey es uno de los peces comerciales más importantes de Buenos Aires y una de las especies clave de la cadena alimenticia en la región, por lo que resultan relevantes estudios histopatológicos adicionales para asegurar la salud de los ...

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“…Chronic exposures to low concentrations of arsenic were associated with diseases such as hepatic fibrosis, cirrhosis, hepatocellular carcinoma, melanosis, hyperkeratosis, diabetes mellitus, immunological disorders, pulmonary infections, hypertension, and cardiovascular and neuromuscular diseases (Ahmed et al 2013). Similarly, exposure to high environmental nickel levels was related to an increased risk of oral carcinoma and premalignant lesion development (Tsai et al 2017).…”

Section: Introductionmentioning

confidence: 99%

Tobacco influence in heavy metals levels in head and neck cancer cases

Bandeira

Almeida

Carta

et al. 2018

Environ Sci Pollut Res

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Heavy metals intoxication is known to be risk factors for various diseases, including cancer. These metals may be presented in food and soil as well as in leaf and tobacco smoke. The aim of this study was to correlate the exposure to heavy metals stemming from tobacco and head and neck squamous cell carcinoma carcinogenesis. Analysis of lead, copper, manganese, arsenic, chromium, and cadmium by atomic absorption spectrophotometry was performed in whole blood samples from 91 patients: 68 smokers with oral cavity, pharynx, or laryngeal cancer; 8 non-smokers with oral or larynx cancer; and 15 non-cancer smokers with tobacco-related diseases (control group). No differences were found in metals quantifications, except a significant difference was observed (p = 0.0223) with higher mean in copper levels for non-smokers with cancer. The present study concluded, for the groups evaluated, it was not possible to prove the relationship between the studied metals in the development of the neoplasm. On the other hand, the results of copper demonstrated a correlation with smokers with cancer and lower levels of circulating copper.

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Arsenic induced toxicity and histopathological changes in gill and liver tissue of freshwater fish, tilapia (Oreochromis mossambicus)

Cited by 117 publications

References 25 publications

Histopathological and haematological response of male rainbow trout (Oncorhynchus mykiss) subjected to butachlor

Histopathological and haematological response of male rainbow trout (Oncorhynchus mykiss) subjected to butachlor

HISTOPATHOLOGICAL CHANGES IN LIVER AND GILLS OF Odontesthes bonariensis INHABITING A LAKE WITH HIGH CONCENTRATIONS OF ARSENIC AND FLUORIDE (CHASICÓ LAKE, BUENOS AIRES PROVINCE)

Tobacco influence in heavy metals levels in head and neck cancer cases

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