Arsenic contamination of groundwater and prevalence of arsenical dermatosis in the Hetao plain area, Inner Mongolia, China

Guo, Xiao juan; Fujino, Yoshihisa; Kaneko, Satoshi; Wu, Kegong; Xia, Yajuan; Yoshimura, Takesumi

doi:10.1007/978-1-4615-0793-2_16

Cited by 56 publications

(45 citation statements)

References 1 publication

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“…Rates of As induced skin lesions were 44.8% or 37.1%, respectively, in two As contaminated areas where 96.2% or 69.3% wells were detected with As over 0.05 mg/L in water. The prevalence of skin lesions was higher in older residents over 40 years old and showed no gender differences (Guo et al, 2001). …”

Section: Non-malignant Skin Lesionsmentioning

confidence: 98%

“…Skin lesions are one of the most common features of chronic As poisoning and these lesions are used as a diagnostic criteria of endemic As poisoning in Inner Mongolia, China (Guo et al, 2001). …”

Section: Dose-response Relationship Between Arsenic Exposure and Arsementioning

confidence: 99%

“…The authors explained this lack of consistency as possibly due to several factors including: recent As exposure from occasional-use water sources; some undefined environmental, nutritional or genetic factors including potentially As metabolism. Guo et al (2001) reported a dose-response relationship between As exposure and skin lesions in areas of Inner Mongolia. Rates of As induced skin lesions were 44.8% or 37.1%, respectively, in two As contaminated areas where 96.2% or 69.3% wells were detected with As over 0.05 mg/L in water.…”

Section: Non-malignant Skin Lesionsmentioning

confidence: 99%

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Chronic health effects in people exposed to arsenic via the drinking water: dose?response relationships in review

Yoshida¹

2004

Toxicology and Applied Pharmacology

504

260

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Chronic arsenic (As) poisoning has become a world wide public health issue.Most human As exposure occurs from consumption of drinking water containing high amounts of inorganic As (iAs). In this paper, epidemiological studies conducted on the dose-response relationships between iAs exposure via the drinking water and related adverse health effects are reviewed. Before the review, the methods for evaluation of the individual As exposure are summarized and classified into two types, i.e. the methods depending on As concentration of the drinking water and the methods depending on biological monitoring for As exposure; certain methods may be applied as optimum As exposure indexes to study dose-response relationship based on various As exposure situation. Chronic effects of iAs exposure via drinking water include skin lesions, neurological effects, hypertension, peripheral vascular disease, cardiovascular disease, respiratory disease, diabetes mellitus, and malignancies including skin cancer.The skin is quiet sensitive to arsenic and skin lesions are some of the most common and earliest non-malignant effects related to chronic As exposure. The increase of prevalence in the skin lesions has been observed even at the exposure levels in the range of 0.005-0.01 mg/L As in drinking waters. Skin, lung, bladder, kidney, liver and uterus are considered as sites As-induced malignancies, and the skin is though to be perhaps the most sensitive site. Prospective studies in large area of endemic As poisoning, like Bangladesh or China, where the rate of malignancies is expected to increase within the next several decades, will help to clarify the dose-response relationship between As exposure levels and adverse health effects with enhanced accuracy.

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Section: Non-malignant Skin Lesionsmentioning

confidence: 98%

Section: Dose-response Relationship Between Arsenic Exposure and Arsementioning

confidence: 99%

Section: Non-malignant Skin Lesionsmentioning

confidence: 99%

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Chronic health effects in people exposed to arsenic via the drinking water: dose?response relationships in review

Yoshida¹

2004

Toxicology and Applied Pharmacology

504

260

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“…In Bangladesh , West Bengal (India) (Rahman et al, 2001), and parts of China (Guo et al, 2001), millions of people have arsenic concentrations in their drinking water above 50 g/l, with some exceeding 1000 g/l (Chakraborti et al, 2003). Widespread exposure raises the need for urgent short term solutions which can be accomplished with limited resources throughout a population, and which are sustainable until long term solutions such as piped water systems are eventually installed.…”

Section: Widespread Arsenic Exposure and The Difficulty Of Community mentioning

confidence: 99%

Arsenic drinking water regulations in developing countries with extensive exposure

Smith¹,

Smith²

2004

Toxicology

115

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“…Since the first cases of chronic As poisoning were observed in the Xinjiang autonomous region in 1980 (Wang and Huang, 1994), new endemic areas, such as the Hetao and Huhot basins in Inner Mongolia (Guo et al, 2001) or the Datong Basin in Shanxi Province , have been progressively identified. The Chinese government has published policies to prevent and control the endemic arsenicosis and a large budget has been allocated for the identification of As-contaminated areas and affected population (Luong et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

Predicting the risk of arsenic contaminated groundwater in Shanxi Province, Northern China

Zhang

Rodríguez‐Lado

Johnson

et al. 2012

Environmental Pollution

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a b s t r a c tShanxi Province is one of the regions in northern China where endemic arsenicosis occurs. In this study, stepwise logistic regression was applied to analyze the statistical relationships of a dataset of arsenic (As) concentrations in groundwaters with some environmental explanatory parameters. Finally, a 2D spatial model showing the potential As-affected areas in this province was created. We identified topography, gravity, hydrologic parameters and remote sensing information as explanatory variables with high potential to predict high As risk areas. The model identifies correctly the already known endemic areas of arsenism. We estimate that the area at risk exceeding 10 mg L À1 As occupies approximately 8100 km 2 in 30 counties in the province.

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Arsenic contamination of groundwater and prevalence of arsenical dermatosis in the Hetao plain area, Inner Mongolia, China

Cited by 56 publications

References 1 publication

Chronic health effects in people exposed to arsenic via the drinking water: dose?response relationships in review

Chronic health effects in people exposed to arsenic via the drinking water: dose?response relationships in review

Arsenic drinking water regulations in developing countries with extensive exposure

Predicting the risk of arsenic contaminated groundwater in Shanxi Province, Northern China

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