Arrival Time Parametric Imaging: A New Ultrasound Technique for Quantifying Perfusion of Kidney Grafts

Fischer, Thomas; Filimonow, S.; Rudolph, J; Morgera, Stanislao; Budde, Klemens; Slowinski, Torsten; Ebeling, V; Taymoorian, Kasra; Giessing, Markus; Thomas, Anke

doi:10.1055/s-2006-927269

Cited by 26 publications

(20 citation statements)

References 5 publications

(8 reference statements)

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“…Furthermore, our analysis demonstrated that the B+US-CD/PD/B-flow examination underestimated the size of ischemic areas [19,20,21]. CE-US however was able to show the true extent of the ischemia with a clear delineation of its borders.…”

Section: Discussionmentioning

confidence: 94%

Perfusion Disturbances of Kidney Graft Parenchyma Evaluated with Contrast-Enhanced Ultrasonography in the Immediate Period following Kidney Transplantation

et al. 2013

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Purpose: Graft parenchyma perfusion disturbances (GPPD) in transplanted kidneys are common in the early postoperative period. Rapid and accurate diagnosis can guide proper treatment, preventing graft dysfunction. Methods: One hundred and eighty patients, who underwent kidney transplantation (KTx), were examined in the immediate postoperative period using real-time ultrasonography (B-mode) with color and power Doppler (US-CD/PD) and B-flow ultrasound, as well as with an additional protocol of contrast-enhanced ultrasonography (CE-US). Regions of GPPD were localized and measured. The number and size of these areas were compared between the two acquisition techniques. Follow-up examinations were carried out 6 months postoperatively. Results: CE-US revealed more GPPDs and showed them more precisely than the B+US-CD/PD/B-flow technique. Moreover, in the CE-US examination, ischemic foci had statistically significant higher echogenicity in comparison to normal parenchyma, were larger and better visualized (better circumscribed) than in B+US-CD/PD/B-flow. Conclusion: CE-US allows the visualization of GPPD caused by occlusion of small arteries. It is a noninvasive, safe, real-time method, which has many advantages over standard B+US-CD/PD/B-flow examinations, and we recommend it as a routine diagnostic procedure in the early postoperative period following KTx.

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Section: Discussionmentioning

confidence: 94%

Perfusion Disturbances of Kidney Graft Parenchyma Evaluated with Contrast-Enhanced Ultrasonography in the Immediate Period following Kidney Transplantation

et al. 2013

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“…Patterns of parametric imaging (software by Toshiba, Japan) of arrival time and time-to-peak were evaluated [11]. Postprocessing -parametric imaging included: arrival time (AT) and time-to-peak (TP) images with different 3 time ranges: 7 s, 14 s, 21 s (of color scale that covered the respective time range).…”

Section: Methodsmentioning

confidence: 99%

Application of parametric ultrasound contrast agent perfusion studies for differentiation of hyperplastic adrenal nodules from adenomas—Initial study

Słapa

Kasperlik-Załuska²,

Migda

et al. 2015

European Journal of Radiology

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“…Images were analysed retrospectively on a workstation (EchoPack, GE) using software (Q-analyze) dedicated to quantitative analysis of ultrasound signal intensity [12–14]. Based on time-intensity curves (TIC), changes in the values for two regions of interest (ROI) were analysed.…”

Section: Methodsmentioning

confidence: 99%

Standardowe badanie w prezentacji B oraz badanie z podaniem środka kontrastowego (US-CE) - porównanie przydatności badań ultrasonograficznych w ocenie echostruktury i wielkości krwiaków u pacjentów po przeszczepie nereki – wstępne doniesienia.

et al. 2012

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SummaryBackground:During routine ultrasonographic examination in B presentation, performed as a standard diagnostic procedure during the early post-operative period, the most important problem with the interpretation of the images of perirenal haematoma is their ability to change in time. The aim of this work was to assess the echogenicity and the size of perirenal haematomas in patients after kidney transplant during routine examinations in B presentation and during examinations enhanced with a contrast medium (CE-US).Material/Methods:Thirty-seven patients after kidney transplant were examined using standard examination in B presentation. Sixteen patients (7 women and 9 men) with isoechogenic and hypoechogenic areas visualized within the renal parenchyma, who were suspected of perirenal haematoma, underwent a CE-US examination after intravenous administration of sculpture hexafluoride (dose: 2.4 ml/examination). Using time-intensity curves (TIC), changes in the values were analysed for two areas of interest (ROI): in the renal parenchyma and in the areas identified during standard US as haematomas. Identical examination protocols and dynamic data loops allowed the acquisition of identical kidney cross-sections and enabled measuring the echogenicity and thickness of the abnormalities at the same location.Results:During the routine B presentation examination, the average difference between haematoma and the renal cortex was 5 dB. When performing US-CE examination, a significantly greater difference in echogenicity was observed and reached 31 dB. In six patients, the size of haematomas was comparable using both techniques, whereas in ten patients lesions visualized in B presentation were smaller than in the US-CE examination.Conclusions:The US-CE examination demonstrated a greater, statistically significant, difference in the echogenicity of perirenal haematomas compared to the routine examination in B presentation. This method enabled a more detailed assessment of the size of haematomas in the perirenal space that appeared during early post-operative period.

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Arrival Time Parametric Imaging: A New Ultrasound Technique for Quantifying Perfusion of Kidney Grafts

Abstract: Acute rejection and perirenal haematoma are associated with a delayed signal increase in the renal cortex. This information can be provided with a single image with standardised colour display of the temporal course of USCM inflow.

Cited by 26 publications

References 5 publications

Perfusion Disturbances of Kidney Graft Parenchyma Evaluated with Contrast-Enhanced Ultrasonography in the Immediate Period following Kidney Transplantation

Perfusion Disturbances of Kidney Graft Parenchyma Evaluated with Contrast-Enhanced Ultrasonography in the Immediate Period following Kidney Transplantation

Application of parametric ultrasound contrast agent perfusion studies for differentiation of hyperplastic adrenal nodules from adenomas—Initial study

Standardowe badanie w prezentacji B oraz badanie z podaniem środka kontrastowego (US-CE) - porównanie przydatności badań ultrasonograficznych w ocenie echostruktury i wielkości krwiaków u pacjentów po przeszczepie nereki – wstępne doniesienia.

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