Aromatisation de la testostérone par le placenta de cobaye in vitro

Adessi, G. L.; Goutte-Coussieu, C; Nhuan, Tran Quang; Jayle, M F

doi:10.1016/s0300-9084(76)80445-2

Cited by 6 publications

(1 citation statement)

References 4 publications

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“…The columns were prepared according to the method described by Adessi et al (1976). A glass column (1 x 12 cm) equipped with a 50-ml bowl was filled with Dowex AG1-X2 resin, chloride form, 200-400 mesh (Bio-Rad), suspended in distilled water.…”

Section: Introductionmentioning

confidence: 99%

In vitro effect of a fish gonadotropin on aromatase and 17 β-hydroxysteroid dehydrogenase activities in the ovary of the rainbow trout (Salmo gairdneri Rich.)

Sire¹,

Dépêche²

1981

Reprod. Nutr. Dévelop.

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Summary. Aromatase activity has been studied in the rainbow trout ovary in a perifusion system. During early vitellogenesis, as in other stages of the annual cycle, the ovaries were capable of aromatizing androstenedione and testosterone. Aromatase activity increased from the postovulatory stages to exogenous vitellogenesis.When highly purified salmon glycoprotein maturational gonadotropin was added to the medium (50 ng/ml), the androstenedione/testosterone ratio was reduced by half. This indicates a stimulation of 17p-hydroxysteroid dehydrogenase activity favourizing the formation of testosterone. At a concentration of 50, 150 or 300 ng/ml, the gonadotropin inhibited between 13 and 38 p. 100 of the aromatase enzymatic activity.Introduction.

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Section: Introductionmentioning

confidence: 99%