2018
DOI: 10.4172/2161-0959.1000315
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Are Testosterone and BCL6 Critical Players in Cisplatin-Induced Nephrotoxicity in Rats?

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“…Cumulative effects of these events conclude in acute renal failure [ 5 ]. It has been found that nephrotoxicity due to Cisplatin can be monitored through diuretics and hydration regimens in many patients, but the frequency of Cisplatin nephrotoxicity still occurs in about one-third of patients undergoing Cisplatin treatment [ 32 ]. Amifostine is approved by the US Food and Drug Administration for Use in reducing progressive nephrotoxicity of repeated Cisplatin dosing in patients with advanced ovarian cancer.…”
Section: Introductionmentioning
confidence: 99%
“…Cumulative effects of these events conclude in acute renal failure [ 5 ]. It has been found that nephrotoxicity due to Cisplatin can be monitored through diuretics and hydration regimens in many patients, but the frequency of Cisplatin nephrotoxicity still occurs in about one-third of patients undergoing Cisplatin treatment [ 32 ]. Amifostine is approved by the US Food and Drug Administration for Use in reducing progressive nephrotoxicity of repeated Cisplatin dosing in patients with advanced ovarian cancer.…”
Section: Introductionmentioning
confidence: 99%