Are subtypes of affective symptoms differentially associated with change in cognition over time: A latent class analysis

Singham, Timothy; Brooker, Helen; Creese, Byron; Aarsland, Dag; Hampshire, Adam; Ballard, Clive; Corbett, Anne; Desai, Roopal; Stott, Joshua

doi:10.1016/j.jad.2022.04.139

Cited by 5 publications

(3 citation statements)

References 52 publications

(58 reference statements)

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“…This study is the first to identify bridge symptoms linking mental health and cognitive impairment in aging PLWH. Using a strategy that estimates cognitive impairment from single to multiple dimensions, our network analysis provided detailed information about their interrelationships and strength compared to previous studies that only focused on pairwise correlations [49,50]. Problem-solving task and motor acted as the crucial bridge symptoms linking mental health and cognitive impairment, which could be potential targets for intervention in mental health and cognitive function improvement in aging PLWH.…”

Section: Discussionmentioning

confidence: 99%

Exploring Interrelationships between Mental Health Symptoms and Cognitive Impairment in Aging People Living with HIV in China

Ma,

Yu,

Fan

et al. 2024

Dement Geriatr Cogn Disord

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Introduction: Mental health symptoms and cognitive impairment are highly prevalent and intertwined among aging people living with HIV (PLWH). This study aimed to assess the interrelationships and strength of connections between individual mental health symptoms and cognitive impairment. It sought to identify specific symptoms linking mental health and cognitive impairment in aging PLWH. Methods: Participants in Sichuan Older People with HIV Infections Cohort Study (SOHICS) were recruited between November 2018 and April 2021 in China. Mental health symptoms, including depression and anxiety, were assessed by the Patient Health Questionnaire (PHQ-9) and General Anxiety Disorder-7 (GAD-7), respectively. Cognitive impairment was assessed by the Montreal Cognitive Assessment-Basic (MoCA-B). Partial correlation network was used to depict the interrelationships between mental health symptoms and cognitive impairment, and bridge strength was used to identify specific symptoms linking mental health and cognitive impairment. Results: Of the 1,587 recruited participants with a mean age of 63.0 years old, 47.0% had mild or severe cognitive impairment. Network analysis revealed that cognitive function, visual perception, and problem-solving task of the MoCA-B were negatively correlated with appetite, energy, and motor of the PHQ-9, respectively. Based on their interrelationships, problem-solving task and motor acted as bridge symptoms. Conclusion: Problem-solving task and motor may be potential intervention targets to reduce the overall risk of mental health symptoms and cognitive impairment. Future research could assess the feasibility and effectiveness of specific interventions designed to the two symptoms in aging PLWH.

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Section: Discussionmentioning

confidence: 99%

Exploring Interrelationships between Mental Health Symptoms and Cognitive Impairment in Aging People Living with HIV in China

Ma,

Yu,

Fan

et al. 2024

Dement Geriatr Cogn Disord

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“…Responses to items that were scored 0 indicated absence of symptoms, whereas responses to items that were scored 1, 2 or 3 indicated presence of symptoms. The dichotomization was performed because participants showed a positively skewed distribution toward 0 on the PHQ items ( Singham et al, 2022 ). The fitness index of the LCA was estimated according to the Akaike information criterion (AIC), Bayesian information criterion (BIC), sample size-adjusted BIC (SABIC), and entropy values.…”

Section: Methodsmentioning

confidence: 99%

Subgroups of depressive symptoms in Korean police officers: A latent class analysis

Kang

Bang

2023

Preventive Medicine Reports

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“…Notably, while cognitive impairment can accompany psychiatric complications, psychiatric symptoms, including depression and anxiety, may also increase cognitive decline. Specifically, changes in visual and spatial working memory are more likely to be associated with psychiatric symptoms (Singham et al, 2022). A population-based cohort study found that anxiety symptoms were associated with worsened processing speed and cognitive impairment (Gulpers et al, 2022).…”

Section: Introductionmentioning

confidence: 99%

Psychometric properties of the Cognitive Functioning Self-Assessment Scale in community-dwelling adults: A cross-sectional online survey

Chung

Nam²,

Li³

et al. 2023

Front. Psychol.

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BackgroundThe Cognitive Functioning Self-Assessment Scale (CFSS) was developed to allow the self-assessment of perceived cognitive functioning. It has been tested with satisfactory reliability and validity but was not available for the Chinese population. This study aimed to adapt and validate the Chinese version of the CFSS for community-dwelling adults.MethodsA cross-sectional study of a sample of 1,002 Chinese adults from the general population was conducted online (July–August 2022). The Chinese version of the CFSS with 18 items was created through translation, cognitive debriefing, and psychometric evaluation. Exploratory factor analysis (EFA) was performed on the first half of the randomly split sample. A model derived from EFA was confirmed by confirmatory factor analysis (CFA) in the second half of the sample. The model fits were further evaluated with and without subgrouping by age, gender, and education level. Internal consistency was assessed using Cronbach’s alpha (α) and McDonald’s omega hierarchical coefficients (ωH).ResultsEFA (n = 460) revealed a three-factor solution, including spatio-temporal orientation, attention, and memory, which explained 51% of the total variance. The second-order CFA (n = 510) demonstrated a good fit: CFI = 0.951, TLI = 0.944, RMSEA = 0.054, SRMR = 0.040. A second-order multiple-group analysis showed that the structure was invariant by age, gender, and education level. The total CFSS score was significantly associated with the Chinese version of the nine-item Patient Health Questionnaire (r = 0.56, p< 0.001) and the Chinese version of the seven-item General Anxiety Disorder (r = 0.53, p<0.001). The internal consistency reliability was satisfactory, with α = 0.94 and ωH = 0.84. The item-total correlation coefficients ranged from 0.58 to 0.72.ConclusionThe Chinese version of the CFSS possesses good item characteristics, satisfactory validity, and reliability for assessing self-reported cognitive functioning among community-dwelling adults. It is a feasible and appropriate self-assessment instrument to examine cognitive functioning in the Hong Kong Chinese population, which contributes to monitoring and developing strategies to prevent and manage cognitive impairment and disorders for the public’s cognitive health and well-being.

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Are subtypes of affective symptoms differentially associated with change in cognition over time: A latent class analysis

Cited by 5 publications

References 52 publications

Exploring Interrelationships between Mental Health Symptoms and Cognitive Impairment in Aging People Living with HIV in China

Exploring Interrelationships between Mental Health Symptoms and Cognitive Impairment in Aging People Living with HIV in China

Subgroups of depressive symptoms in Korean police officers: A latent class analysis

Psychometric properties of the Cognitive Functioning Self-Assessment Scale in community-dwelling adults: A cross-sectional online survey

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