A hospitalist admits a 75-year-old grandfather and retired factory worker with NYHA class IV congestive heart failure from ischemic cardiomyopathy and chronic obstructive pulmonary disease for the fifth time in the last 6 months for dyspnea. He has had progressive debility over the last year and is now bedbound. In the early morning hours before his admission, he experienced a witnessed aspiration event and presented to the emergency department with agonal respirations. He is lethargic and unable to verbally communicate or follow commands. His brother, the designated healthcare proxy, meets with the hospitalist, and they decide that the patient would wish to focus his care on the promotion of comfort at this point. The hospitalist removes medications and tests that are not focused on comfort, changes the vital signs to temperature and respiratory rate only every shift, and begins to consider adding orders to address symptom management in the last hours of life. To treat the patient's tachypnea (respirations approximately 22-24/min) with accessory muscle use, the hospitalist considers her pharmacologic options.