Are Obesity and Adenoma Development Associated as Colorectal Cancer Precursors?

Freitas, Bianca Astrogildo de; Loth, Carlos Alberto Tomatis; Swarowsky, G. L.; LourenÇo, Graziela Morais; Fillmann, Lúcio Sarubbi; Fillmann, Henrique Sarubbi; Santos, Marcio Lustosa; Padoin, Alexandre Vontobel

doi:10.1590/0102-672020190001e1500

Cited by 6 publications

(4 citation statements)

References 22 publications

(20 reference statements)

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“…Evidências indicaram que a proporção de tecido adiposo abdominal, tecido adiposo visceral em particular, é uma correlata chave e talvez um fator principal de problemas de saúde relacionados à obesidade, porque tem sido associado com um risco aumentado para comorbidades como o diabetes mellitus tipo 2, acidente vascular cerebral, apneia do sono, hipertensão, dislipidemia e alguns tipos de câncer (Trinks, et al, 2019;Freitas, et al, 2020;Wendler, et al, 2022;Sasaki, et al, 2021).…”

Section: Resultsunclassified

Avaliação do estado nutricional e consumo alimentar de pacientes com depressão

Barros

Albuquerque²,

Lourenço³

et al. 2022

RSD

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Avaliar se há associação entre o estado nutricional e o consumo alimentar de pacientes com depressão. O estudo foi desenvolvido no Centro de Atenção Psicossocial (CAPS), localizado na cidade de Sobral - CE, com 100 pacientes com transtorno depressivo, na faixa etária entre 20 e 59 anos, ambos os sexos. Foram coletados dados socioeconômicos, antropométricos, e o consumo alimentar através de um Questionário de Frequência Alimentar (QFA). O projeto foi aprovado pelo Comitê de Ética em Pesquisa, sob parecer nº 2.596.743. Dos 100 participantes da amostra, 67% (n= 67) foram mulheres, na faixa etária “menor que 39 anos”, 55% (n= 55), a cor negra 51% (n = 51), a união consensual∕casado 56% (n= 56) e a renda de até um salário mínimo 55% (n=55). Ao analisarmos o estado nutricional, ambos os sexos, apresentaram um número maior de participantes com sobrepeso e obesidade. A prevalência de excesso de peso foi de 89%, sendo 58% do sexo feminino e 31% do sexo masculino. Quanto ao consumo alimentar não houve diferença entre os participantes, segundo o Índice de Massa Corpórea (IMC) (p > 0,05). Há alta proporção de excesso de peso entre os pacientes avaliados e este não foi associado ao consumo alimentar.

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Section: Resultsunclassified

Avaliação do estado nutricional e consumo alimentar de pacientes com depressão

Barros

Albuquerque²,

Lourenço³

et al. 2022

RSD

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show abstract

“…There are some hypotheses for this increase, one of which is the increase in the number of emergency cases, very common in situations of underdiagnosis, and the increase in the number of cases seen is the increase in diagnoses in patients under 45 years of age. (FREITAS et al,2020).…”

Section: Resultsmentioning

confidence: 99%

Sociodemographic and Clinical Profile of Patients Undergoing Surgery for Colorectal Cancer in a Teaching Hospital

Antoniazzi¹,

Marçal²,

Cau³

et al. 2022

JHS

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Tracing the sociodemographic and clinical profile of patients undergoing colorectal surgery for cancer in a teaching hospital between 2010 and 2019, and estimating factors related to discharge and readmission. For this purpose, data will be collected, processed and analyzed from medical records of patients undergoing colorectal procedures at Hospital Santa Casa de Misericórdia de Vitória, which serves patients in the public and private network. The survey was approved by the CEP of EMESCAM with an opinion consubstantiated 4,167,383. Data from 350 patients were included. There was a higher proportion of patients aged 45 to 75 years (72.3%), female (53.7%), brown (71.1%), with a partner (53.7%), and attended by the SUS (88.9%). Most procedures were elective (78.3%), with a predominance of tumors in the ascending colon, followed by rectum and sigmoid colon. Most patients did not undergo ostomy. Approximately 46% of the individuals analyzed had metastasis, and 80% of the cases had free surgical margins. Comparing sociodemographic and clinical variables to the reason for discharge and postoperative readmission, it is suggested that unfavorable outcomes are associated with the nature of the surgery (p < 0.01) and marital status (p < 0.01). Conclusion: The present study suggests that there is a higher mortality in patients without a partner and undergoing emergency surgery, as well as a longer hospital stay in the latter group. This result is important in establishing public policies that improve screening and provide early treatment for this health problem, and generate data to improve hospital management.

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“…With the growing obesity epidemic, and a consequent increase in the number of procedures for its treatment and control, there is a greater interest in acquiring knowledge, experience and skills for the surgical and anesthetic management of these patients 10,21 . These involve several factors, from measures for postoperative analgesia, presence of nausea, vomiting and effective peristalsis, which contribute to lower morbidity and mortality and early discharge from hospital 4 .…”

Section: Introduction Omentioning

confidence: 99%

Roux-in-Y Gastrojejunal Bypass: Which Anesthetic Technique Has Best Results?

Ruzzon

Nassif

Prigol

et al. 2021

ABCD, arq. bras. cir. dig.

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Background: As the number of bariatric operations increases, there is a greater interest in knowledge, experience and skills in the operative and anesthetic management of obese people. Anesthetic recovery is an important point in the therapeutic approach and less adverse effects delaying discharge of these patients are necessary to be kept in mind by the surgical team. Aim: To compare anesthetic-analgesic techniques in the opioid-sparing era through epidural administration of local anesthetic associated with low-dose morphine vs. clonidine and analyze the impact of analgesia on the effectiveness of postoperative recovery by comparing these two techniques. Methods: Randomized, double-blind clinical trial with 66 patients candidates for Roux-en-Y gastrojejunal bypass divided into two groups: morphine group and clonidine group. Multimodal analgesia included epidural anesthesia with 0.375% ropivacaine 20 ml at the eighth thoracic vertebra with the association of morphine (morphine group) at a dose of 15 mcg / kg or clonidine (clonidine group) at a dose of 1 mcg / kg. Results: The groups were homogeneous and statistical significance was found when analyzing the difference in pain between them in the first postoperative period. The pain was higher in the clonidine group, as in this period, analgesic rescue was also better in this group. In the other times, there was no significance in the differences regarding pain and rescue. The return of intestinal motility in the morphine group was earlier in the first postoperative period. Nausea, vomiting and hospital discharge did not show significant differences between groups. Conclusion: Epidural anesthesia with low-dose morphine allowed less pain during the entire hospital stay, with a positive impact on patient recovery.

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Are Obesity and Adenoma Development Associated as Colorectal Cancer Precursors?

Cited by 6 publications

References 22 publications

Avaliação do estado nutricional e consumo alimentar de pacientes com depressão

Avaliação do estado nutricional e consumo alimentar de pacientes com depressão

Sociodemographic and Clinical Profile of Patients Undergoing Surgery for Colorectal Cancer in a Teaching Hospital

Roux-in-Y Gastrojejunal Bypass: Which Anesthetic Technique Has Best Results?

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