Are endometrial polyps from pre-menopausal women similar to post-menopausal women? An immunohistochemical comparison of endometrial polyps from pre- and post-menopausal women

McGurgan, Paul; Taylor, L.J.; Duffy, Srg; O’Donovan, Peter

doi:10.1016/j.maturitas.2005.12.003

Cited by 63 publications

(27 citation statements)

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“…18 Failure of usual control mechanisms for apoptotic regulation may be possible causative factors for the promotion of endometrial polyp growth. 19 An overexpression of Bcl-2 which plays a significant role in regulation of apoptosis was reported in endometrium in the study of McGurgan et al 19 These tumors may depend on the intricate balance between proliferation and apoptosis. Based on the proposed etiologies, similar mechanisms may contribute to the development of cervical polyps.…”

Section: Discussionmentioning

confidence: 97%

Are Obesity, Diabetes, and Hypertension Risk Factors for Cervical Polyps?

Uçar¹,

Uçar²,

İlhan³

et al. 2016

Turkiye Klinikleri J Gynecol Obst

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226ervical polyps are common benign neoplasms of the cervix in adult women.1 They are believed to develop as a result of focal hyperplasia. They usually develop in multiparous women during the fifth Are Obesity, Diabetes, and Hypertension Risk Factors for Cervical Polyps?A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : To investigate whether diabetes, hypertension, and obesity can be considered risk factors for cervical polyps. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : The hospital-based case-control study was carried out. We retrospectively reviewed the records of 307 consecutive patients with cervical polyps. A control group consisting of 3 women per case-matched by the same age, same parity, same menopausal status and the same presenting symptoms. These groups were compared with respect of diabetes, hypertension and obesity prevalence. R Re es su ul lt ts s: : The study included a total of 212 patients eligible for analysis in cervical polyp group, and a matched control group consisting of 636 women without cervical polyp. Women with cervical polyp had higher body mass index than the controls, but the difference was not statistically significant (p=0.72). The prevalence of obesity was significantly higher in the cervical polyp group than the controls (p=0.016). A statistically significant correlation was found between obesity and cervical polyps (OR: 1.351, CI: 1.062-1,718). There was no significant difference between the groups with respect to the prevalence of diabetes (p=0.795) and hypertension (p=0.703). C Co on nc cl lu us si io on n: : Obesity appears to be a risk factor for cervical polyps. Obese women should receive special attention for potential coexistence of cervical polyps as part of their gynecological evaluation. This study supports the importance of weight management for the preventive plan of cervical polyps.K Ke ey y W Wo or rd ds s: : Cervix uteri; polyps; diabetes mellitus; hypertension; obesity Ö ÖZ ZE ET T A Am ma aç ç: : Diyabet, hipertansiyon ve obezitenin servikal polipler için risk faktörü olup olmadığını araştırmaktır. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Hastane tabanlı vaka-kontrol çalışması oluşturuldu. 307 ardışık servikal polip hastasının kayıtları retrospektif olarak değerlendirildi. Her servikal polip hastası için, aynı yaş, aynı parite, aynı menopozal durumda ve aynı başvuru şikayeti ile gelen 3 kontrol hastası belirlendi. Gruplar hipertansiyon, diyabet ve obezite prevalansı açısından karşılaştırıldı. B Bu ul lg gu ul la ar r: : Çalışma kriterlerine uygun servikal polibi olan 212 hasta vaka grubuna ve servikal polibi olmayan eşleştirilmiş 636 hasta kontrol grubuna dahil edildi. Servikal polip hastalarının beden kitle indeksi, kontrol grubundan daha fazlaydı, ancak bu fark istatistiksel anlamlı değildi (p=0,72). Obezite prevalansı servikal polip grubunda, kontrol grubundan istatistiksel olarak anlamlı düzeyde yüksek bulundu (p=0,016). Obezite ve servikal polipler arasında istatistiksel anlamlı düzeyde korelasyon saptandı (OR: 1,351, ...

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Section: Discussionmentioning

confidence: 97%

Are Obesity, Diabetes, and Hypertension Risk Factors for Cervical Polyps?

Uçar¹,

Uçar²,

İlhan³

et al. 2016

Turkiye Klinikleri J Gynecol Obst

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“…They have glands, stroma and blood vessels that contribute to increased glycodelin secretion in the cavum uteri (12,13). The common assumption is that glycodelin may "leak" from blood vessels near polyps and dissolve in saline, which is used during hysteroscopy uterine flushing (14,20).…”

Section: еXperimental Group Control Groupmentioning

confidence: 99%

Analysis of Glycodelin Levels Before and After Hysteroscopic Polypectomy in Infertile Patients

Sorak

Dević

2018

Serbian Journal of Experimental and Clinical Research

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Glycodelin (or placental protein 14) is a glycoprotein located in the glandular and thin epithelium of the endometrium. It is considered an important factor in the implantation process, and its traces can be found in elevated concentrations in the uterine fl ushing obtained at the time of implantation, while in the prolif ANALYSIS OF GLYCODELIN LEVELS BEFORE AND AFTER HYSTEROSCOPIC POLYPECTOMY IN INFERTILE PATIENTS

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“…Схильність проліферативної патології ендометрія до тривалого, рецидивуючого перебігу [5], а при відсутності адекватного лікуван-ня гіперпластичних процесів ендометрія (ГПЕ) й до розвитку злоякісних захворювань слизової оболонки матки [6] зумовлює актуальність проблеми.…”

Section: вступunclassified

Endometrial pathology and reproductive profile of women in late reproductive and premenopausal age

Korniyenko¹

2017

ScienceRise: Medical Science

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Are endometrial polyps from pre-menopausal women similar to post-menopausal women? An immunohistochemical comparison of endometrial polyps from pre- and post-menopausal women

Cited by 63 publications

References 18 publications

Are Obesity, Diabetes, and Hypertension Risk Factors for Cervical Polyps?

Are Obesity, Diabetes, and Hypertension Risk Factors for Cervical Polyps?

Analysis of Glycodelin Levels Before and After Hysteroscopic Polypectomy in Infertile Patients

Endometrial pathology and reproductive profile of women in late reproductive and premenopausal age

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