Are Depressive Symptoms a Risk Factor for Mortality in Elderly Japanese American Men?: The Honolulu-Asia Aging Study

Takeshita, Junji; Masaki, Kamal; Ahmed, Iqbal Ike K.; Foley, Daniel J.; Li, Yuan Qing; Chen, Randi; Fujii, Daryl; Ross, G. Webster; Petrovitch, Helen; White, Lon R.

doi:10.1176/appi.ajp.159.7.1127

Cited by 79 publications

(70 citation statements)

References 33 publications

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“…In line, the mortality risks of depressed participants remained increased in participants who were independent in activities of daily living, in participants with good cognitive function, and in those without chronic diseases. These results demonstrate that the excess of mortality is not only caused by co-morbidity and frailty, as was already mentioned by other authors (Wulsin, 2000;Takeshita et al, 2002). Furthermore, antidepressive pharmacotherapy was almost nonexistent in our population (Stek et al, 2004a), which makes it unlikely that treatment effects of depression increase mortality.…”

Section: Discussionsupporting

confidence: 84%

Does depression in old age increase only cardiovascular mortality? The Leiden 85‐plus Study

Vinkers

Stek

Gussekloo

et al. 2004

Int J Geriat Psychiatry

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Section: Discussionsupporting

confidence: 84%

Does depression in old age increase only cardiovascular mortality? The Leiden 85‐plus Study

Vinkers

Stek

Gussekloo

et al. 2004

Int J Geriat Psychiatry

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“…The summed score of the 11-question version CES-D ranged from 0-33 and the present study defined conditions with a summed score >9 as depressive symptoms (29). Several validation studies have shown that CES-D has a reasonable psychometric property in South Korea and other East-Asian countries (30)(31)(32)(33) .…”

Section: Outcome Variables and Covariatesmentioning

confidence: 74%

Association between change in employment status and new-onset depressive symptoms in South Korea – a gender analysis

Kim¹,

Subramanian

Sorensen

et al. 2012

Scand J Work Environ Health

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“…Several cohort studies have reported similar relative risk values of 1.02-3.36 (15)(16)(17). It remains unclear how depressive symptoms affect coronary heart disease and other complications, although several explanations have been put forward.…”

Section: Discussionmentioning

confidence: 99%

Depressive Mood and Abdominal Fat Distribution in Overweight Premenopausal Women

et al. 2005

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Objective: There is increasing evidence that depressive mood is associated with central obesity, but little is known about the association between depression and abdominal fat distribution. This study investigated this relationship in premenopausal women. Research Methods and Procedures:We recruited 101 overweight premenopausal women who had no eating disorders as defined using the DSM IV criteria. Depressive mood was assessed using Zung's Self-Rating Depression Scale (SDS). Areas of visceral (VAT) and subcutaneous (SAT) adipose tissue at the level of vertebral body L 4 -L 5 were measured using computed tomography. Associations of VAT, SAT, and the ratio of VAT to SAT with natural logarithmic transformation [(ln)]SDS were evaluated using linear regression. Anthropometric indices and physical fitness were also measured. Information on socioeconomic status, education level, and alcohol and smoking habits was obtained using self-administered questionnaires. A hospital nutritionist assessed nutritional status. All of these factors were adjusted for as possible confounding factors in the analyses. Results: The (ln)SDS score showed a positive association with the area of VAT, even after adjusting for the confounders mentioned above (p Ͻ 0.01). BMI, waist circumference, maximal oxygen uptake, and age were also associated with the area of VAT (all p Ͻ 0.05). In contrast, the (ln)SDS score was not associated with SAT (p Ͼ 0.10). Discussion: We showed that depressive mood is associated with VAT, not with SAT, in overweight premenopausal women. These findings may explain some of the association between depression and coronary heart disease. More studies are needed to elucidate the causal relationship.

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Are Depressive Symptoms a Risk Factor for Mortality in Elderly Japanese American Men?: The Honolulu-Asia Aging Study

Abstract: Depressive symptoms are a risk factor for mortality in elderly people, particularly in physically healthy individuals.

Cited by 79 publications

References 33 publications

Does depression in old age increase only cardiovascular mortality? The Leiden 85‐plus Study

Does depression in old age increase only cardiovascular mortality? The Leiden 85‐plus Study

Association between change in employment status and new-onset depressive symptoms in South Korea – a gender analysis

Depressive Mood and Abdominal Fat Distribution in Overweight Premenopausal Women

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