2023
DOI: 10.1016/j.jafr.2023.100505
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Araçá (Psidium Cattleianum Sabine) ethanol extracts increase lifespan and alleviate oxidative stress in Caenorhabditis elegans

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Cited by 4 publications
(4 citation statements)
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“…The phytochemical evaluation demonstrated that the red and yellow araçá had similar amounts of total phenolic compounds, around 5209-5517 µg CAE/mL, respectively (Table 1). A similar profile of araçá phenolic compounds was observed in previous work performed by our laboratory, where yellow araçá showed a larger amount of total phenols, followed by flavonoid content, than red araçá [39]. On the other hand, a different profile was found by Biegelmeyer and colleagues when comparing the red and yellow araçá and demonstrated that red araçá total content of phenolic compounds, expressed in fresh weight, was more abundant than yellow (501.33-292.03 mg of GAE/100 g, respectively) [7].…”
Section: Resultssupporting
confidence: 89%
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“…The phytochemical evaluation demonstrated that the red and yellow araçá had similar amounts of total phenolic compounds, around 5209-5517 µg CAE/mL, respectively (Table 1). A similar profile of araçá phenolic compounds was observed in previous work performed by our laboratory, where yellow araçá showed a larger amount of total phenols, followed by flavonoid content, than red araçá [39]. On the other hand, a different profile was found by Biegelmeyer and colleagues when comparing the red and yellow araçá and demonstrated that red araçá total content of phenolic compounds, expressed in fresh weight, was more abundant than yellow (501.33-292.03 mg of GAE/100 g, respectively) [7].…”
Section: Resultssupporting
confidence: 89%
“…Chaves and colleagues (2018), evaluated the biological proprieties of Brazil berries, including red and yellow araçá methanolic extract, and the cytotoxic effect on the cancer cells lines A549 (non-small cell lung cancer cells), RD (rhabdomyosarcoma), and DU145 (prostate carcinoma); however, none of the extracts were able to reduce cell viability in all tested cancer cell lines [45]. We suggest that the effect observed in the red araçá extract and not in the yellow one was due to the presence of anthocyanins content in their composition, as was observed in the composition of the majority phenolic compounds of red araçá [39]. Furthermore, other studies using fruit extracts rich in anthocyanins, such as grapes (Vitis vinifera), blueberries (Vaccinium myrtillus L.), and chokeberry (Aronia meloncarpa E.), were able to inhibit the growth of HT-29 cells [46].…”
Section: Resultsmentioning
confidence: 66%
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“…In vivo studies in model organisms have directly demonstrated that carotenoids protect against ageing. Several studies used C. elegans and showed that supplementation with carotenoid-rich extracts from plant sources not only protect against oxidative stress but also increase lifespan [20,[24][25][26][27][28][29]. Moreover, individual carotenoids improve health in C. elegans.…”
Section: Mechanisms By Which Phytoene Impacts Ageingmentioning
confidence: 99%