Aquaculture as yet another environmental gateway to the development and globalisation of antimicrobial resistance

Cabello, Felipe C.; Godfrey, Henry P.; Buschmann, Alejandro H.; Dölz, Humberto

doi:10.1016/s1473-3099(16)00100-6

Cited by 339 publications

(196 citation statements)

References 101 publications

Supporting

Mentioning

192

Contrasting

Unclassified

Order By: Relevance

“…The use of eco-friendly alternatives, such as vaccines, to prevent diseases thereby minimizing antibiotic use has been suggested to be one of the effective ways of containing ABR (Cabello et al, 2016;Coyne et al, 2016). In ASPs, veterinarians are supposed to be in the lead in educating clients to vaccinate their animals against preventable diseases.…”

Section: Discussionmentioning

confidence: 99%

“…The cost of developing a new antibiotic has been estimated to be US$1 billion (Huttner et al, 2013), but no new antibiotic is expected to be on the market until 2018 at the earliest (Bartlett, 2011;Cisneros et al, 2014). antibiotic use) is critical for ASPs to be successfully implemented (Cotta et al, 2014;Viale et al, 2015;Cabello et al, 2016). Thus, veterinarians (as clinicians and educators) play a critical role in ABS and for successful implementation of ASP (Bowater, 2015;Coyne et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

“…Such interventions are aimed at strengthening the concept of One Health at the humananimal-environment interface because antibiotic-resistant organisms easily pass from one environment to the other and vice versa (WHO, 2014;Cabello et al, 2016;Kock et al, 2016). It is established that containment of ABR could only be possible if containment strategies are employed in all healthcare environments (Abbo et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Veterinarians’ Perception, Knowledge and Practices of Antibiotic Stewardship in Enugu State Southeast, Nigeria

Anyanwu¹,

Kolade²

2017

Not Sci Biol

View full text Add to dashboard Cite

A cross-sectional survey utilizing structured questionnaires was used to study the veterinarians' perception, knowledge and practices of antibiotic stewardship (ABS) in Enugu State, Southeastern Nigeria. Data obtained were analyzed using chi-square on SPSS (Version 15.0) at a significance level of P < 0.05 to determine possible associations between variables and perceptions/knowledge about ABS. Out of 280 respondents, 41 (17.1%) had heard about ABS. Minority of the respondents perceived/knew that using antibiotics only when necessary (6.4%, 18), administering antibiotics at the appropriate dose (6.4%, 18) and administering antibiotics for appropriate duration in every case (4.3%, 12) were among the principles of ABS. The study also showed that age, gender, qualification, years of practice and locations did not exert any influence (P > 0.05) on the awareness of respondents about ABS. More than one-third of the respondents wrongly perceived that increasing the use of broad-spectrum antibiotics (35.4%, 99) is one of the goals of ABS, whereas the minority of the respondents rightly perceived/knew that minimizing toxicity and other adverse effects (16.8%, 47) and reducing antibiotic resistance (ABR) (43.2%, 121) are also goals of ABS. Only 21.4% (60) had overall knowledge of ABS. Prescribing antibiotics without seeing/examining the patient, prescribing antibiotics for any case suspected to be infectious, prescribing broad-spectrum antibiotics despite availability of narrow-spectrum antibiotics, prescribing different classes/types of antibiotics concurrently to ensure therapeutic efficacy, prescribing overdose of antibiotics to ensure efficacy and non-consultation of the veterinary formulary/other resources when in doubt during prescription, are some of inappropriate/untoward ABS practices/behaviors/attitudes amongst the respondents. No significant association (P > 0.05) was found between practices of ABS and age, gender, qualification, years of practice and location. In conclusion, the veterinarians' awareness/perception and practices of ABS is abysmally poor in the study area, thus education of Nigerian veterinarians about ABS and the teaching of the principles and practices of ABS during veterinary schools are recommended.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Veterinarians’ Perception, Knowledge and Practices of Antibiotic Stewardship in Enugu State Southeast, Nigeria

Anyanwu¹,

Kolade²

2017

Not Sci Biol

View full text Add to dashboard Cite

show abstract

“…Such differences exemplify the difficulty of AMR because comparable and plausible studies do not always provide black and white answers and can generate opposite conclusions. In the above cases, we suspect that the FAO data may not represent all food animal–related activity, particularly aquaculture in South East Asia where AMR is reported to be rampant . Again, this shows how conclusions from one study can provide different answers than those from parallel studies.…”

Section: Complexity Of Antimicrobial Resistance Across Domesticated Amentioning

confidence: 97%

Complexities in understanding antimicrobial resistance across domesticated animal, human, and environmental systems

Graham

Bergeron

Bourassa

et al. 2019

Annals of the New York Academy of Sciences

119

View full text Add to dashboard Cite

Antimicrobial resistance (AMR) is a significant threat to both human and animal health. The spread of AMR bacteria and genes across systems can occur through a myriad of pathways, both related and unrelated to agriculture, including via wastewater, soils, manure applications, direct exchange between humans and animals, and food exposure. Tracing origins and drivers of AMR bacteria and genes is challenging due to the array of contexts and the complexity of interactions overlapping health practice, microbiology, genetics, applied science and engineering, as well as social and human factors. Critically assessing the diverse and sometimes contradictory AMR literature is a valuable step in identifying tractable mitigation options to stem AMR spread. In this article we review research on the nonfoodborne spread of AMR, with a focus on domesticated animals and the environment and possible exposures to humans. Attention is especially placed on delineating possible sources and causes of AMR bacterial phenotypes, including underpinning the genetics important to human and animal health.

show abstract

“…Este fenómeno subyace en la presión selectiva ejercida por la presencia de residuos de antibióticos en fondos, sedimentos, especies de cultivo y silvestres expuestas involuntariamente (Miranda & Zemelman, 2002;Holmströmn et al, 2003;Miranda & Rojas, 2007;Gainza, 2009;Fernández-Alarcón et al, 2010;Hoa et al, 2011;Ringø et al, 2014;Cabello et al, 2016). Esta situación ha limitado la eficiencia de los antibióticos como herramienta en el manejo de la salud de los cultivos (Moriarty, 1999;Miranda & Rojas, 2007;Reverter et al, 2014;Cabello et al, 2016), al tiempo que se han generado numerosas iniciativas legales tanto en los países productores como en los principales mercados objetivo, para regular su empleo, debido a las implicaciones ambientales y en la salud humana que han generado su mal manejo (Miranda & Zemelman, 2002;Romero et al, 2012;Reverter et al, 2014).…”

Section: Introductionunclassified

Manano oligosacaridos como prebioticos en acuicultura de crustaceos

Gainza¹,

Romero²

2017

lajar

View full text Add to dashboard Cite

RESUMEN.Los prebióticos tienen el potencial de incrementar la eficiencia y sostenibilidad de la producción acuícola. Uno de los prebióticos más promisorios en acuicultura son los Manano oligosacáridos (MOS). Estos MOS son moléculas de carbohidratos complejos derivados de la pared de la célula de la levadura Saccharomyces cerevisiae, que impiden la adhesión de patógenos bacterianos porque actúan bloqueando la adherencia de las lectinas microbianas con los carbohidratos presentes en la superficie de las células intestinales. Esta prevención de la adhesión impide la colonización y proceso infectivo de los patógenos. La ventaja del uso de MOS es que puede prevenir infecciones a través de mecanismos diferentes a los utilizados por los antibióticos. Este artículo muestra los avances obtenidos en uso de MOS como prebióticos en la acuicultura, en particular en el cultivo de crustáceos, donde han generado respuestas positivas en todas las experiencias actuando sobre el incremento del crecimiento, la supervivencia, modulando la respuesta inmune y modificando la morfología del tracto digestivo. La identificación de las cepas que son promovidas o excluidas y la caracterización de la acción moduladora en la microbiota resultante quedan abiertas como uno de los campos a desarrollar en conjunto con la extensión de estos resultados a la práctica productiva. Palabras clave: crustáceos, manano oligosacáridos, MOS, prebióticos, microbiota, crecimiento. Mannan oligosaccharides as prebiotics in crustacean aquacultureABSTRACT. Probiotics have the potential to increase the efficiency and sustainability of aquaculture production. The mannan-oligosaccharides (MOS) are complex carbohydrates derived from the cell wall of the yeast Saccharomyces cerevisiae, which act by blocking adherence of bacterial lectins to carbohydrates on the surface of intestinal cells; this action prevents colonization and infection processes carried out by bacterial pathogens. In this work, we review the current evidence about the use of MOS as prebiotics in shellfish aquaculture, enlightening the positive responses in most of the experiences, such as improvement in growth and survival, modulating the immune response and modifying the morphology of the digestive tract. The identification of strains that are promoted or excluded, and the characterization of the resulting modulating action in gut´s microbiota, remains open as one of the fields to be developed in conjunction with the extension of these results to the productive practice.

show abstract

Aquaculture as yet another environmental gateway to the development and globalisation of antimicrobial resistance

Cited by 339 publications

References 101 publications

Veterinarians’ Perception, Knowledge and Practices of Antibiotic Stewardship in Enugu State Southeast, Nigeria

Veterinarians’ Perception, Knowledge and Practices of Antibiotic Stewardship in Enugu State Southeast, Nigeria

Complexities in understanding antimicrobial resistance across domesticated animal, human, and environmental systems

Manano oligosacaridos como prebioticos en acuicultura de crustaceos

Contact Info

Product

Resources

About