“…Notwithstanding the difficulty in predicting which particular intervention approach works best with which ASD individual [ 2 ], starting from Colby’s theoretical premises [ 11 ] and following the seminal study of Strickland and colleagues [ 12 ], in the last two decades literature surveys [ 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 ] have witnessed an ever-growing number of proposals for approaches falling in the “Technology-based Treatment” category, as denoted in 2009 by the National Autism Center [ 23 ]. The well-established literature regarding the efficacy of the visual modality for ASD people [ 24 , 25 , 26 , 27 ], with a recognized preference for visual stimuli transmitted through electronic screen media [ 25 ] (such as television screens, computer monitors, tablets, smartphones) and a natural propensity for video and video games [ 28 , 29 , 30 , 31 ]), has made Information and Communication Technology (ICT) a first-class option for the investigation of assistive technologies, cognitive rehabilitation tools, and education tools.…”