Approaches for the sustainable production of fucoxanthin, a xanthophyll with potential health benefits

Zarekarizi, Amirreza; Hoffmann, Linn; Burritt, David J.

doi:10.1007/s10811-018-1558-3

Cited by 71 publications

(47 citation statements)

References 121 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Therefore, fucoxanthin is supposed to prevent and alleviate several chronic diseases. For an extensive review please see Peng et al [12] or Zarekarizi et al [24].…”

Section: Introductionmentioning

confidence: 99%

“…The total amount of fucoxanthin in diatoms was found to range from 6.2 to 59.2 mg g -1 of total dry weight depending on the specific production strain and solvent used for extraction [11,[22][23][24]. Thus, the fucoxanthin content of microalgae can be up to 10 times higher compared to conventional sources for this carotenoid like macroalgae [25,26].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Coproduction of EPA and Fucoxanthin with P. tricornutum – A Promising Approach for Up‐ and Downstream Processing

Derwenskus

Schafer

Müller

et al. 2020

Chemie Ingenieur Technik

View full text Add to dashboard Cite

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. Eicosapentaenoic acid (EPA) and fucoxanthin, a carotenoid, provide a broad variety of health benefits in human nutrition. In this study, an up-and downstream process for the coproduction of EPA and fucoxanthin using the diatom Phaeodactylum tricornutum in flat-panel airlift photobioreactors is proposed. The approach represents a promising alternative to conventional sources for both compounds, viz. marine fish and macroalgae. The productivity as well as the biomass-specific product content were optimized during cultivation. Subsequently, both compounds were extracted, separated and purified using pressurized liquids.

show abstract

“…Therefore, fucoxanthin is supposed to prevent and alleviate several chronic diseases. For an extensive review please see Peng et al [12] or Zarekarizi et al [24].…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Coproduction of EPA and Fucoxanthin with P. tricornutum – A Promising Approach for Up‐ and Downstream Processing

Derwenskus

Schafer

Müller

et al. 2020

Chemie Ingenieur Technik

View full text Add to dashboard Cite

show abstract

“…PT is also rich in carotenoids, mainly fucoxanthin, whose concentration is at least ten times higher than that of macroalgae compared to dry matter [40]. Many studies have shown that fucoxanthin has antioxidant, anti-tumor, anti-inflammatory, and anti-obesity effects [41]. Fucoxanthin extract from PT has been reported to have anti-inflammatory, antioxidant and anti-proliferative effects on blood mononuclear cells and on different cell lines [42].…”

Section: Introductionmentioning

confidence: 99%

Protective Action of Ostreococcus Tauri and Phaeodactylum Tricornutum Extracts towards Benzo[a]Pyrene-Induced Cytotoxicity in Endothelial Cells

Goff

Delbrut²,

Quinton³

et al. 2019

Marine Drugs

View full text Add to dashboard Cite

Marine microalgae are known to be a source of bioactive molecules of interest to human health, such as n-3 polyunsaturated fatty acids (n-3 PUFAs) and carotenoids. The fact that some of these natural compounds are known to exhibit anti-inflammatory, antioxidant, anti-proliferative, and apoptosis-inducing effects, demonstrates their potential use in preventing cancers and cardiovascular diseases (CVDs). Benzo[a]pyrene (B[a]P), a polycyclic aromatic hydrocarbon (PAH), is an ubiquitous environmental pollutant known to contribute to the development or aggravation of human diseases, such as cancer, CVDs, and immune dysfunction. Most of these deleterious effects are related to the activation of the polycyclic aromatic hydrocarbon receptor (AhR). In this context, two ethanolic microalgal extracts with concentrations of 0.1 to 5 µg/mL are tested, Ostreoccoccus tauri (OT) and Phaeodactylum tricornutum (PT), in order to evaluate and compare their potential effects towards B[a]P-induced toxicity in endothelial HMEC-1 cells. Our results indicate that the OT extract can influence the toxicity of B[a]P. Indeed, apoptosis and the production of extracellular vesicles were decreased, likely through the reduction of the expression of CYP1A1, a B[a]P bioactivation enzyme. Furthermore, the B[a]P-induced expression of the inflammatory cytokines IL-8 and IL1-β was reduced. The PT extract only inhibited the expression of the B[a]P-induced cytokine IL-8 expression. The OT extract therefore seems to be a good candidate for counteracting the B[a]P toxicity.

show abstract

“…Apart from microalgae, which are being widely used in supplements and other products, many macroalgae, like the brown seaweed wakame ( Undaria pinnatifida ) or the red alga Chondrus crispus are widely consumed in some areas, typically in East Asian countries …”

Section: Importance Of Carotenoids In Agro‐food Health and Diseasementioning

confidence: 99%

“…[14,23] Apart from microalgae, which are being widely used in supplements and other products, many macroalgae, like the brown seaweed wakame (Undaria pinnatifida) or the red alga Chondrus crispus are widely consumed in some areas, typically in East Asian countries. [24,25] Regarding human foods that are produced from animals, carotenoids are found in egg yolks, [26,27] poultry tissues, or the milk, liver, and adipose tissues of domesticated mammals, including cattle, horses, sheep, and goats. [22,28] Furthermore, they are found in the flesh of some fish such as salmon and rainbow trout, as well as in a number of other commonly consumed marine animals (e.g., oyster, clam, scallop, mussel, and sea urchin gonads).…”

Section: Dietary Sources Of Carotenoidsmentioning

confidence: 99%

An Overview of Carotenoids, Apocarotenoids, and Vitamin A in Agro‐Food, Nutrition, Health, and Disease

Meléndez-Martínez

2019

Molecular Nutrition Food Res

179

126

View full text Add to dashboard Cite

Carotenoids are fascinating compounds that can be converted into many others, including retinoids that also play key roles in many processes. Although carotenoids are largely known in the context of food science, nutrition, and health as natural colorants and precursors of vitamin A (VA), evidence has accumulated that even those that cannot be converted to VA may be involved in health‐promoting biological actions. It is not surprising that carotenoids (most notably lutein) are among the bioactives for which the need to establish recommended dietary intakes have been recently discussed. In this review, the importance of carotenoids (including apocarotenoids) and key derivatives (retinoids with VA activity) in agro‐food with relevance to health is summarized. Furthermore, the European Network to Advance Carotenoid Research and Applications in Agro‐Food and Health (EUROCAROTEN) is introduced. EUROCAROTEN originated from the Ibero‐American Network for the Study of Carotenoids as Functional Food Ingredients (IBERCAROT).

show abstract

Approaches for the sustainable production of fucoxanthin, a xanthophyll with potential health benefits

Cited by 71 publications

References 121 publications

Coproduction of EPA and Fucoxanthin with P. tricornutum – A Promising Approach for Up‐ and Downstream Processing

Coproduction of EPA and Fucoxanthin with P. tricornutum – A Promising Approach for Up‐ and Downstream Processing

Protective Action of Ostreococcus Tauri and Phaeodactylum Tricornutum Extracts towards Benzo[a]Pyrene-Induced Cytotoxicity in Endothelial Cells

An Overview of Carotenoids, Apocarotenoids, and Vitamin A in Agro‐Food, Nutrition, Health, and Disease

Contact Info

Product

Resources

About