Approach to the spectrum of Budd-Chiari syndrome: Which patients require portal decompression?

Millikan, William J.; Henderson, J. Michael; Sewell, Charles W.; Guyton, Robert A.; Potts, John R.; Cranford, Clifford A.; Cramer, Anne R.; Galambos, John T.; Wd, Warren

doi:10.1016/s0002-9610(85)80028-3

Cited by 60 publications

(9 citation statements)

References 27 publications

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“…A liver biopsy can also be used as a guide for the therapy, with the presence of necrosis, which suggests a need for porto-systemic shunts, whereas an extensive fibrosis favours a liver transplant as the treatment of choice [10]. Transjuglar portosystemic shunts have also been used to treat these patients [11].…”

Section: Discussionmentioning

confidence: 99%

The Budd-Chiari Syndrome in a Child: A Case Report and Review of the Literature

Misra

Verma²,

Singh³

et al. 2012

JCDR

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The Budd-Chiari Syndrome is associated with hepatic venous outflow obstruction. This syndrome is rare in infants and children. As this syndrome is uncommon, especially in the paediatric age group, misdiagnoses and delays in the diagnosis are frequent. A high index of clinical suspicion along with a radiological aid and a histopathological correlation can lead to an early diagnosis and an appropriate management in such cases.This case report highlights the occurrence of this rare condition in the paediatric age group as well as it redefines the salient features of this syndrome.

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Section: Discussionmentioning

confidence: 99%

The Budd-Chiari Syndrome in a Child: A Case Report and Review of the Literature

Misra

Verma²,

Singh³

et al. 2012

JCDR

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“…Fifty-nine of these 65 patients (91%) underwent operation <18 weeks after the onset of symptoms. The remaining six patients underwent portal decompression surgery 19,21,23,25,26, and 78 weeks after becoming ill. Twelve of the 77 patients were referred to us with advanced cirrhosis, 11-21 months after the onset of symptoms (mean, 15.9 months). These patients were referred too late for portal decompression; they required liver transplantation.…”

Section: Patient Characteristicsmentioning

confidence: 99%

Budd–Chiari Syndrome Revisited: 38 Years’ Experience with Surgical Portal Decompression

Orloff

Isenberg

Wheeler

et al. 2012

Journal of Gastrointestinal Surgery

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“…Venular thrombosis is usually not evident in biopsy specimens. All patients under consideration for surgery should undergo liver biopsy in conjunction with angiography to determine whether the patient will benefit more from a shunt procedure or a liver transplant [135,137] .…”

Section: Hepatic Venographymentioning

confidence: 99%

Hepatic venous outflow obstruction: Three similar syndromes

Bayraktar

Seren²,

Bayraktar³

2007

WJG

116

110

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Our goal is to provide a detailed review of venoocclusive disease (VOD), Budd-Chiari syndrome (BCS), and congestive hepatopathy (CH), all of which results in hepatic venous outflow obstruction. This is the first article in which all three syndromes have been reviewed, enabling the reader to compare the characteristics of these disorders. The histological findings in VOD, BCS, and CH are almost identical: sinusoidal congestion and cell necrosis mostly in perivenular areas of hepatic acini which eventually leads to bridging fibrosis between adjacent central veins. Tender hepatomegaly with jaundice and ascites is common to all three conditions. However, the clinical presentation depends mostly on the extent and rapidity of the outflow obstruction. Although the etiology and treatment are completely different in VOD, BCS, and CH; the similarities in clinical manifestations and liver histology may suggest a common mechanism of hepatic injury and adaptation in response to increased sinusoidal pressure.

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Approach to the spectrum of Budd-Chiari syndrome: Which patients require portal decompression?

Cited by 60 publications

References 27 publications

The Budd-Chiari Syndrome in a Child: A Case Report and Review of the Literature

The Budd-Chiari Syndrome in a Child: A Case Report and Review of the Literature

Budd–Chiari Syndrome Revisited: 38 Years’ Experience with Surgical Portal Decompression

Hepatic venous outflow obstruction: Three similar syndromes

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