Approach to the Adult Kidney Stone Former

Maalouf, Naim M.

doi:10.1007/s12018-011-9111-9

Cited by 13 publications

(9 citation statements)

References 74 publications

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“…A study [10] stated that stone patients have a relative risk of hypercalcemia and hypercalciuria nine to 18 times more than non-stone formers, respectively. Nonetheless, by definition of hypercalcemia (serum calcium > 2.75 mmol/L), only two patients (0.03‰) in our cohort were diagnosed as real hypercalcemia, which consistent with the research of a prospective study [11]. In a large prospective study, calcium intake was measured and high dietary intake was inversely correlated with kidney stone risk (relative risk: 0.56) [12].…”

Section: Discussionsupporting

confidence: 89%

Correlative Analysis Between Severity of Urolithiasis and Laboratory Parameters and Its Implication in Evaluation of the Probable Risk Profile

T.P¹,

Singh²,

Barua³

et al. 2018

World J Nephrol Urol

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Background: Urolithiasis presents serious hazard which significantly elevates the cost of national health expenditure in almost every part of both the hemispheres. There is high risk of hospitalization with loss of valuable human resource and decreased productivity along with it. Risk factors still evade the exact etiology and search for optimal serum panel is still in its infancy. Urolithiasis incidence has gradually increased in last 3 decades which suggests that some constant metabolic and urinary parameters are implicated in the risk of occurrence of urinary stone. The present study is intended to identify a panel of serum parameters, urinary parameters, radiological characteristics and correlating it with the clinical severity of stone disease. Methods: The present study was conducted at the Department of Urology at GMCH Guwahati. The authors retrospectively analyzed 151 patients undergoing stone surgery from a period of January 2016 to August 2017. Data comprised of all serum and urinary examinations done 1 week preoperatively and radiological scans within 1 month before surgery. Spearman test was used to determine correlation and analysis of variance (ANOVA) was applied for comparison between more than two categories. Results: Stone multiplicity was positively correlated with upper tract stone sides (r = 0.530, P < 0.01), large stone volume (r = 0.172, P < 0.02), stone recurrence, urinary infection and urine protein. Upper tract stone sides number was positively correlated with upper tract obstruction sides (r = 0.542, P < 0.03), large stone volume (r =-0.321, P < 0.01). Upper tract obstruction sides number was positively correlated with large stone volume (r =-0.848, P < 0.01). Conclusions: Results demonstrated that urinary tract obstruction and total stone volume significantly correlated with abnormal serum panel, urinary profile and were harbinger of complex stone pattern.

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Section: Discussionsupporting

confidence: 89%

Correlative Analysis Between Severity of Urolithiasis and Laboratory Parameters and Its Implication in Evaluation of the Probable Risk Profile

T.P¹,

Singh²,

Barua³

et al. 2018

World J Nephrol Urol

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“…Management of daily diet can be a major strategy for preventing the recurrence of urolithiasis [ 18 ]. Therefore, we analyzed the relationship between dietary risk factors and urinary stone formation.…”

Section: Discussionmentioning

confidence: 99%

Dietary risk factors for urolithiasis in Korea: A case-control pilot study

et al. 2018

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PurposeDietary factors are one of the main causes of urolithiasis. However, little research has evaluated dietary factors related to urolithiasis in Korea. We investigated the various dietary risk factors for urinary stone formation in Korean people.Materials and MethodsWe conducted a prospective case-control pilot study. A total of 27 patients newly diagnosed with urolithiasis and 20 applicants without urolithiasis were designated as the patients and the control group, respectively. A face-to-face survey was carried out using a food-frequency questionnaire. After adjustment for physical activity level and total energy intake, multivariate logistic regression models were applied to search for risk factors for urolithiasis.ResultsThere were no significant differences between the two groups in gender, age, body mass index, family history, or total energy intake. The physical activity level of the control group was significantly higher than that of the patients (p=0.012). The results of the multivariate logistic regression model demonstrated that intake of carbohydrate (odds ratio [OR], 1.055; 95% confidence interval [CI], 1.012–1.099), protein (OR, 1.101; 95% CI, 1.001–1.211), and cereals (OR, 1.012; 95% CI, 1.002–1.023) could increase the risk for urolithiasis.ConclusionsA higher intake of carbohydrate, protein, and cereal may increase the risk of urinary stone formation among Korean people.

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“…La sobresaturación urinaria de diferentes metabolitos como el calcio, oxalato y úrico influye de manera positiva en la litogénesis, mientras que el aumento en orina de citrato y magnesio disminuye el riesgo de formación de litiasis al actual como inhibidores de la precipitación cristalina (11,12,13). Aunque la composición de la litiasis tiene en cierta manera que ver y se relaciona con las alteraciones metabólicas urinarias (7,14), es cierto que el análisis de los factores en sangre y orina es básico a la hora de establecer medidas profilácticas y preventivas.…”

Section: Discussionunclassified

Study of lithogenic factors in men and women with recurrent nephrolithiasis in the north area of Almeria

Cano-García¹,

Roletto-Salmo²,

Hidalgo-Agulló³

2015

Actual. Med.

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Estudio de factores litogénicos en hombres y mujeres con litiasis urinaria recidivante en el área norte de Almería ResumenObjetivos: Estudiar los principales factores litogénicos en hombres y mujeres con litiasis urinaria recidivante en un área geográfica concreta. Material y Métodos: Estudio transversal que incluye 94 pacientes con litiasis urinaria recidivante desde junio 2014-enero 2015, en los que se realiza evaluación metabólica en sangre, orina ayunas y orina de 24 horas. Se comparan resultados medios de los parámetros estudiados según sexos y porcentaje de los principales factores de riesgo litogénicos. Estudio estadístico con SPSS 20.0, considerando significación estadística p≤0.05. Resultados: De los 94 pacientes incluidos, 60 fueron hombres y 34 mujeres, con edades medias de 49 y 51 años respectivamente, sin diferencias significativas. Los hombres presentan mayor excreción urinaria de calcio, úrico, oxalato y sodio que las mujeres y un mayor porcentaje de hiperuricosuria (>750 mg/24h) respecto a las mujeres. En las mujeres destaca en relación a los hombres un mayor porcentaje de hipovitaminosis D (<20ng/ml). La excreción de sodio se relaciona con la excreción de diferentes factores de riesgo litógeno, entre ellos el calcio. Los pacientes con pH en rango 5.5-7 presentan niveles de citrato más bajos que pacientes con pH<5.5. Conclusión:El estudio de factores litogénicos con evaluación metabólica tiene interés por los cambios que se producen según las regiones estudiadas y según otros factores como el sexo y el pH urinario. AbstractObjectives: To study the main lithogenic factors in men and women with recurrent nephrolithiasis in a particular geographical area. Material and Methods: Cross-sectional study including 94 patients with recurrent nephrolithiasis from June 2014 to January 2015, in which metabolic evaluation is performed on blood, fasting urine and 24 hours urine. Average results of the parameters studied by sex and percentage of the main lithogenic risk factors are compared. Statistical analysis with SPSS 20.0, considering statistical significance p≤0.05. Results: Of the 94 patients enrolled, 60 were men and 34 women, with mean ages of 49 and 51 years respectively, without significant difference. Men have higher urinary excretion of calcium, uric, sodium and oxalate respect women and men presented a higher percentage of hyperuricosuria (> 750 mg / 24 h) compared to women. In women, respect men, presented higher percentage of hypovitaminosis D (<20 ng / ml). Urinary sodium excretion is related to different lithiasis risk factors, including calcium. Patients with pH range 5.5-7 presented lower levels of citrate than patients with pH <5.5. Conclusion:The study of lithogenic factors with metabolic evaluation is interested in the changes that occur as the regions studied and according to other factors such as sex and urinary pH. Enviado: 14-02-2015 Revisado: 25-06-2015 Aceptado: 10-08-2015 Study of lithogenic factors in men and women with recurrent nephrolithiasis in the north area of Almeria Act...

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Approach to the Adult Kidney Stone Former

Cited by 13 publications

References 74 publications

Correlative Analysis Between Severity of Urolithiasis and Laboratory Parameters and Its Implication in Evaluation of the Probable Risk Profile

Correlative Analysis Between Severity of Urolithiasis and Laboratory Parameters and Its Implication in Evaluation of the Probable Risk Profile

Dietary risk factors for urolithiasis in Korea: A case-control pilot study

Study of lithogenic factors in men and women with recurrent nephrolithiasis in the north area of Almeria

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