Approach to Aquatic Skin Infections

Vasagar, Brintha; Jain, Vasudha; Germinario, Anthony; Watson, Heber J.; Ouzts, Michael; Presutti, R. John; Álvarez, Salvador

doi:10.1016/j.pop.2018.05.010

Cited by 9 publications

(5 citation statements)

References 55 publications

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“…The infection caused by this organism is classified as a waterborne disease. Other bacteria causing waterborne-related infections include Mycobacterium marinum , Aeromonas spp., Erysipelothrix rhusiopathiae , Shewanella spp., and Vibrio vulnificus [ 4 , 5 ]. Reservoirs of E. tarda are aquatic animals that live in fresh or brackish water environments (such as river mouths) such as fish (eel, flounder, catfish, largemouth bass, and rainbow trout), cockles, reptiles, turtles, and alligators [ 6 ].…”

Section: Discussion/conclusionmentioning

confidence: 99%

Genetically Confirmed Edwardsiella tarda Peritonitis was Associated with Improper Caregiver’s Hand Hygiene during Peritoneal Dialysis Bag Exchange

Chieochanthanakij

Manuprasert

Udomsantisuk

et al. 2022

Case Rep Nephrol Dial

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Edwardsiella tarda is a Gram-negative bacillus and is responsible for waterborne disease. This is the first case report of peritoneal dialysis (PD)-associated peritonitis caused by genetically confirmed E. tarda, which was transmitted from the caregiver’s hand during PD bag exchange. Aside from that, the caregiver was a fishmonger and a gastrointestinal carrier of the pathogen. Prior to the onset of peritonitis, the caregiver reported that she did not wash her hands every time when performing the PD bag exchange. Although extraintestinal edwardsiellosis usually poses a poor outcome, PD-associated peritonitis with this species is paradoxical if diagnosed early, and treatment is promptly provided, as presented here. This case emphasizes the importance of hand hygiene in preventing environment-bound infection in patients on PD and demonstrates the unusual route of infection, contamination during PD bag exchange.

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Section: Discussion/conclusionmentioning

confidence: 99%

Genetically Confirmed Edwardsiella tarda Peritonitis was Associated with Improper Caregiver’s Hand Hygiene during Peritoneal Dialysis Bag Exchange

Chieochanthanakij

Manuprasert

Udomsantisuk

et al. 2022

Case Rep Nephrol Dial

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“…Vibrio, the most strongly and significantly increased bacterial taxon (Figure 1B), is well known for its role as the cholera pathogen (Conner et al, 2016). Because the species of Vibrio mainly live in seawater or brackish water (Vasagar et al, 2018), people should be very careful when consuming seafoods or when exposed to seawater. These results indicate that the accumulation of the pathogenic microbiota is a possible reason for the pathogenesis of psoriasis.…”

Section: Discussionmentioning

confidence: 99%

Microbiome and Metabolome Analyses Reveal Novel Interplay Between the Skin Microbiota and Plasma Metabolites in Psoriasis

Chen

He²,

et al. 2021

Front. Microbiol.

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Psoriasis is a chronic inflammatory skin disease that affects millions of people worldwide. There is still no effective approach for the clinical treatment of psoriasis. This is largely due to the lack of understanding of the pathological mechanism. Here, we comprehensively characterized the skin microbiome and plasma metabolome alterations of psoriasis patients. We observed that some pathogenic bacteria, including Vibrio, were significantly increased in psoriasis patients. The metabolomics results showed alterations in some metabolic pathways, especially pathways for lipid metabolism. In addition, microbiome-specific metabolites, including bile acids and kynurenine, were significantly changed. Correlation analysis revealed the interplay between the skin microbiota and plasma metabolites, especially between Vibrio and several lipids. Our results provide new evidence for the interplay between the skin microbiome and plasma metabolites, which is dramatically disrupted in psoriasis patients. This study also revealed the mechanism underlying the pathogenesis of psoriasis.

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“…Characterized as invasions of the epidermis and adjacent tissues by virulent microorganisms, due to the presence of injuries and other risk factors, they initially generate common signs of local inflammation with a potential risk of evolution to various pathological processes, depending on the nature of the invading microbe ( DiNubile and Lipsky, 2004 ; Dryden, 2010 ; Clebak and Malone, 2018 ). Naturally, the epidermis is colonized by several types of microorganisms and, when it comes to bacteria, the ones most commonly detected on the skin of adult individuals belong to the Staphylococcus , Streptococcus , and Corynebacterium genera ( Cefalu et al, 2017 ; Byrd et al, 2018 ; Vasagar et al, 2018 ). Among the main bacterial skin infections are impetigo, erysipelas, cellulitis, folliculitis, abscesses, and necrotizing fasciitis ( Clebak and Malone, 2018 ).…”

Section: Pathological Processes and Clinical Manifestationsmentioning

confidence: 99%

“…Among the main bacterial skin infections are impetigo, erysipelas, cellulitis, folliculitis, abscesses, and necrotizing fasciitis ( Clebak and Malone, 2018 ). Noteworthy, when such diseases are contracted through prior exposure to aquatic environments, the polymicrobial etiology of the infection must be taken into account, especially with regards to the presence of unusual microorganisms, such as Aeromonas ( Vasagar et al, 2018 ).…”

Section: Pathological Processes and Clinical Manifestationsmentioning

confidence: 99%

Aeromonas and Human Health Disorders: Clinical Approaches

et al. 2022

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The genus Aeromonas comprises more than 30 Gram-negative bacterial species and naturally inhabitants from aquatic environments. These microorganisms, commonly regarded as pathogens of fish and several other animals, have been gaining prominence on medical trial due to its ability to colonize and infect human beings. Besides water, Aeromonas are widely spreaded on most varied sources like soil, vegetables, and food; Although its opportunistic nature, they are able to cause infections on immunocompromised or immunocompetent patients. Aeromonas species regarded as potential human pathogens are usually A. hydrophila, A. caviae, and A. veronii biovar sobria. The main clinical manifestations are gastrointestinal tract disorders, wound, and soft tissue infections, as well as septicemia. Regarding to antibiotic responses, the bacteria present a diversified susceptibility profile and show inherence resistance to ampicillin. Aeromonas, as an ascending genus in microbiology, has been carefully studied aiming comprehension and development of methods for detection and medical intervention of infectious processes, not fully elucidated in medicine. This review focuses on current clinical knowledge related to human health disorders caused by Aeromonas to contribute on development of efficient approaches able to recognize and impair the pathological processes.

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Approach to Aquatic Skin Infections

Cited by 9 publications

References 55 publications

Genetically Confirmed <b><i>Edwardsiella tarda</i></b> Peritonitis was Associated with Improper Caregiver’s Hand Hygiene during Peritoneal Dialysis Bag Exchange

Genetically Confirmed <b><i>Edwardsiella tarda</i></b> Peritonitis was Associated with Improper Caregiver’s Hand Hygiene during Peritoneal Dialysis Bag Exchange

Microbiome and Metabolome Analyses Reveal Novel Interplay Between the Skin Microbiota and Plasma Metabolites in Psoriasis

Aeromonas and Human Health Disorders: Clinical Approaches

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