Aeromonas and Human Health Disorders: Clinical Approaches

Pessoa, Rafael Bastos Gonçalves; Oliveira, Weslley Felix de; Correia, Maria Tereza dos Santos; Fontes, Adriana; Coelho, Luana Cassandra Breitenbach Barroso

doi:10.3389/fmicb.2022.868890

Cited by 56 publications

(38 citation statements)

References 171 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…was first isolated from pneumonia, wound infections, septicemia, and abortion in horses, cattle, and pigs in 1987 [ 24 ]. It is known as a threat to aquaculture systems and human health, causing a high death rate [ 3 , 25 ]. As an important member of Aeromonas , A. veronii is pathogenic to both aquatic and terrestrial animals [ 7 , 8 , 26 ].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Isolation and Identification of Aeromonas veronii in Sheep with Fatal Infection in China: A Case Report

et al. 2023

View full text Add to dashboard Cite

According to the findings of a sheep breeding farm in Shaanxi, China, 2.53% (15/594) of sheep exhibited respiratory (clinical) symptoms such as dyspnoea, nasal discharge, wet cough, fever, and progressive emaciation. Although multi-drug treatment strategies (including ampicillin, tylosin, florfenicol, and ceftiofur) have been attempted to improve clinical outcomes, they have only been met with limited success, with a mortality rate of 40%. Ultimately, Aeromonas veronii (A. veronii) was identified as the causative pathogen for respiratory disease. The rates of symptomatic and asymptomatic sheep positive to A. veronii were 64.28% (95% CI 52.25–76.31%) and 8.02% (95% CI 6.96–9.08%), respectively. Pathogenicity tests demonstrated that the A. veronii is pathogenic to sheep and mice. The results of the antibiotic susceptibility tests revealed that the strain was sensitive to cefotaxime, gentamicin, and enrofloxacin and resistant to ampicillin, ceftiofur, amoxicillin, kanamycin, neomycin, streptomycin, tetracycline, florfenicol, and tylosin. We suggest that the combination of cefotaxime and gentamicin is an effective treatment based on the results of an antimicrobial susceptibility test, which exhibited good therapeutic efficacy. To the best of our knowledge, this is the first report in which pathogenic A. veronii has been documented as the cause of death in sheep in China. We concluded that pathogenic A. veronii poses a potential risk to the industry of sheep husbandry. This study’s findings can help guide prevention and treatment plans for A. veronii infection in sheep.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Pathogenicity results revealed that the strain is pathogenic to both sheep and mice. Thus, A. veronii is not only an important threat to the sheep industry, but also poses a potential threat to human health, as the infection may spread to humans via the consumption of undercooked meat contaminated with A. veronii [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

Isolation and Identification of Aeromonas veronii in Sheep with Fatal Infection in China: A Case Report

et al. 2023

View full text Add to dashboard Cite

show abstract

“…To the best of our knowledge, no report mentions Aeromonas sobria as a new candidate for heavy metals removal. Aeromonas species generally associated with human infections include A. caviae, A. schubertii, A. hydrophila, A. veronii (biovars veronii and sobria), and A. jandaei 30 ; however, biochemically distinct A. veronii biovar sobria have been predominantly found in clinical isolates 31 . Our results show that A. sobria can tolerate high concentrations of different heavy metals.…”

Section: Discussionmentioning

confidence: 99%

Aeromonas sobria as a potential candidate for bioremediation of heavy metal from contaminated environments

Qurbani

Khdir

Sidiq

et al. 2022

Sci Rep

View full text Add to dashboard Cite

The uncontrolled discharge of industrial wastes causes the accumulation of high heavy metal concentrations in soil and water, leading to many health issues. In the present study, a Gram-negative Aeromonas sobria was isolated from heavily contaminated soil in the Tanjaro area, southwest of Sulaymaniyah city in the Kurdistan Region of Iraq; then, we assessed its ability to uptake heavy metals. A. sobria was molecularly identified based on the partial amplification of 16S rRNA using novel primers. The sequence was aligned with 33 strains to analyze phylogenetic relationships by maximum likelihood. Based on maximum tolerance concentration (MTC), A. sobria could withstand Zn, Cu, and Ni at concentrations of 5, 6, and 8 mM, respectively. ICP-OES data confirmed that A. sobria reduced 54.89% (0.549 mM) of the Cu, 62.33% (0.623 mM) of the Ni, and 36.41% (0.364 mM) of the Zn after 72 h in the culture medium. Transmission electron microscopy (TEM) showed that A. sobria accumulated both Cu and Ni, whereas biosorption was suggested for the Zn. These findings suggest that metal-resistant A. sobria could be a promising candidate for heavy metal bioremediation in polluted areas. However, more broadly, research is required to assess the feasibility of exploiting A. sobria in situ.

show abstract

“…Although there have been no reports of outbreaks of A. hydrophila in Japan in recent years, it is still challenge as a causative agent of diarrheal infections in other parts of the world. 38) Well water may be used as drinking water in times of disaster. Therefore, it is necessary to use gastrointestinal infection-causing bacteria as indicator bacteria for the safety and quality of well water.…”

Section: Physicochemical Characteristics Of Well Water and Bacterial ...mentioning

confidence: 99%

Microbial Water Quality Assessment of Private Wells Using 16S rRNA Gene Amplicon Sequencing with a Nanopore Sequencer

Mimura

Koizumi

Wada

et al. 2023

Biological & Pharmaceutical Bulletin

View full text Add to dashboard Cite

Private wells are used daily worldwide as convenient household water sources. In Japan, where water supply coverage is high, well water is occasionally used for non-potable purposes, such as irrigation and watering. Currently, the main microbiological test of well water is designed to detect Escherichia coli, which is an indicator of fecal contamination, using culture methods. Water use such as watering generates bioaerosols, which may cause airborne infection. However, many causative bacteria of aerosol-derived infections, such as Legionella spp., are difficult to detect using culture methods. Thus, more comprehensive modern assessment is desirable for securing the microbiological quality of well water. Here, the bacterial community structure of five private wells located in different environments was examined using the rapid and portable MinION sequencer, which enabled us to identify bacteria to the species level based on full-length 16S ribosomal RNA (rRNA) gene sequences. The results revealed the differences in the bacterial community structures of water samples from the five wells and detected Legionella pneumophila and Aeromonas hydrophila as new candidate microbial indicators. The comprehensive analysis method used in this study successfully detected bacteria causing opportunistic infections, which are difficult to detect by conventional methods. This approach is expected to be routinely applied in the future as a highly accurate method for assessing the microbiological quality of private well water.

show abstract

Aeromonas and Human Health Disorders: Clinical Approaches

Cited by 56 publications

References 171 publications

Isolation and Identification of Aeromonas veronii in Sheep with Fatal Infection in China: A Case Report

Isolation and Identification of Aeromonas veronii in Sheep with Fatal Infection in China: A Case Report

Aeromonas sobria as a potential candidate for bioremediation of heavy metal from contaminated environments

Microbial Water Quality Assessment of Private Wells Using 16S rRNA Gene Amplicon Sequencing with a Nanopore Sequencer

Contact Info

Product

Resources

About