Appraisals of Bangladeshi Medicinal Plants Used by Folk Medicine Practitioners in the Prevention and Management of Malignant Neoplastic Diseases

Abstract

Cancer is a group of diseases which is categorized to differentiate into diverse cell types and move around in the body to sites of organogenesis that is key to the process of tumor genesis. All types of cancer fall into the group of malignant neoplastic diseases. In Bangladesh, cancer is now one of the foremost killer diseases and its personal, social, and economic bearing are huge. Plant-derived natural compounds (vincristine, vinblastine, etoposide, paclitaxel, camptothecin, topotecan, and irinotecan) are useful for the treatment of cancer. Since there is no extensive ethnobotanical research study in Bangladesh regarding the traditional uses of medicinal plants against neoplasms, therefore, a randomized ethnopharmacological surveys were carried out in 3 districts of Bangladesh to learn more about the usage of anticancer medicinal plants and their chemical constituents having antineoplastic activity. Comprehensive interviews were conducted to the folk medicine practitioners and medicinal plants as pointed out by them were photographed, collected, deposited, and identified at the Bangladesh National Herbarium. The various plant parts have been used by the healers which included whole plant, leaves, fruits, barks, roots, and seeds. This study evaluated considerable potential for discovery of novel compounds with less side effects in the management and prevention of malignancy in cancer.

Acute and subchronic toxicity profile of methanol extract of leaves of Fimbristylis miliacea (L.) Vahl

“…Traditional medicines are widely used to treat severe diseases including fever, pain, diabetes, in some cases cancer, hepatitis, several skin and lever diseases etc. which also supports the statement that chemo-toxicological profile of these traditional folklore remedies should be revealed [7] , [8] .…”

Effects of Alcoholic Extracts of Bangladeshi Mangrove Acanthus ilicifolius Linn. (Acanthaceae) Leaf and Stem on Atherogenic Model of Wistar Albino Rats

“…A. ilicifolius is acknowledged for its rich sources of several phytochemical constituents like steroids, triterpenoids, saponins, flavonoids, alkaloids, and tannins [ 3 ]. The whole and distinct plant parts have been employed for the purpose of therapeutic aid [ 60 , 61 ]. In our present study, alcoholic extracts of A. ilicifolius leaf and stem have been recruited to investigate its potentiality against atherosclerosis in the high-fat diet-fed rat model.…”

A narrative review of the ethnomedicinal usage of Cannabis sativa Linnaeus as traditional phytomedicine by folk medicine practitioners of Bangladesh

“…They enjoy considerable trust and support from their patients thanks to their holistic approach to treatment (Biswas et al 2011 ). Kabirajes rely mainly on medicinal plants, dispensing medications for several health disorders and diseases including psychosis, cardiovascular disorders, eye infections, malaria, leucorrhea, leprosy, helminthic infections, urinary tract infections, sexually transmitted diseases, snakebite treatment, diabetes, gastrointestinal disorders, tumor, and cancer (Ahmed and Azam 2014 , Azam et al 2014 , 2015 , 2016 , Hasan et al 2012 , 2015 , Hossan et al 2010 , Mollik et al 2009 , Rahmatullah et al 2010a , 2010b , 2010c , 2010h , 2012 , 2012a ). Each Kabiraj normally keeps his or her knowledge of medicinal plants within the family and passes this knowledge through from generation to generation.…”