Applications of Raman spectroscopy in dentistry part II: Soft tissue analysis

Abstract

Raman spectroscopy is rapidly moving from an experimental technique for the analysis of biological molecules to a tool for the real-time clinical diagnosis and in situ evaluation of the oral tissue in medical and dental research. The purpose of this study is to identify various applications demonstrates its role in the disclosure of dysplasia and malignancy but also in performing guided biopsies, diagnosing sialoliths, and assessment of surgical margins. Raman spectroscopy is used to identify the molecular structures and its components to give substantial information about the chemical structure properties of these molecules. In this paper, we acquaint the utilization of Raman spectroscopy in analyzing the soft tissues in relation to dentistry.

Genetic Analysis of Genealogy from Dental Y-STR DNA with Raman Spectra Method: Literature Review

“…You need a very large database of family names you have 14 . Participant surnames appear to be predictable from published whole-genome sequence data when combined with published non-genetic data, thus raising privacy concerns regarding the anonymity of enrollment in medical genetics research 15 .…”

Mechanical-chemical coupling in Temporomandibular Joint disc

“…A key approach to tackle this problem is the combination of stress-strain analysis and vibrational spectroscopy [18,19]. In particular, the use of Raman spectroscopy for in situ investigations on real soft tissue has demonstrated to be a powerful tool for an accurate molecular description [20]. Raman spectroscopy has real advantages for biomedical applications, as it is non-destructive, non-invasive, fast and provides information at the molecular and structural level.…”