Applications of plant-based nanoparticles in nanomedicine: A review

Mohammadzadeh, Vahideh; Barani, Mahmood; Amiri, Mohammad Sadegh; Yazdi, Mohammad Ehsan Taghavizadeh; Hassanisaadi, Mohadeseh; Rahdar, Abbas; Varma, Rajender S.

doi:10.1016/j.scp.2022.100606

Cited by 82 publications

(48 citation statements)

References 161 publications

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“…The potential of plant-based nanoparticles to treat different cancers is being extensively studied and well reviewed [76] and the application of silver and gold nanoparticles to treat cancers is a very active area of research investigations [76][77][78][79][80]. Recent studies revealed that the use of the various metallic nanoparticles in medical sciences has various applications, such as bio-imaging [81][82][83][84], bio-sensing [85][86][87], and drug delivery [88][89][90] of nutraceuticals [23,26,[91][92][93][94][95][96][97][98][99], and pharmaceuticals [17,20,31,100], which could affect disposition [13,24,25,[27][28][29][30]32,33,[101][102][103][104][105][106][107]…”

Section: Introductionmentioning

confidence: 99%

Green Synthesis of a Novel Silver Nanoparticle Conjugated with Thelypteris glandulosolanosa (Raqui-Raqui): Preliminary Characterization and Anticancer Activity

et al. 2022

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In the last decade, the green synthesis of nanoparticles has had a prominent role in scientific research for industrial and biomedical applications. In this current study, silver nitrate (AgNO3) was reduced and stabilized with an aqueous extract of Thelypteris glandulosolanosa (Raqui-raqui), forming silver nanoparticles (AgNPs-RR). UV-vis spectrophotometry, dynamic light scattering (DLS), and scanning transmission electron microscopy (STEM) were utilized to analyze the structures of AgNPs-RR. The results from this analysis showed a characteristic peak at 420 nm and a mean hydrodynamic size equal to 39.16 nm, while the STEM revealed a size distribution of 6.64–51.00 nm with an average diameter of 31.45 nm. Cellular cytotoxicity assays using MCF-7 (ATCC® HTB-22™, mammary gland breast), A549 (ATCC® CCL-185, lung epithelial carcinoma), and L929 (ATCC® CCL-1, subcutaneous connective tissue of Mus musculus) demonstrated over 42.70% of MCF-7, 59.24% of A549, and 8.80% of L929 cells had cell death after 48 h showing that this nanoparticle is more selective to disrupt neoplastic than non-cancerous cells and may be further developed into an effective strategy for breast and lung cancer treatment. These results demonstrate that the nanoparticle surfaces developed are complex, have lower contact angles, and have excellent scratch and wear resistance.

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Section: Introductionmentioning

confidence: 99%

Green Synthesis of a Novel Silver Nanoparticle Conjugated with Thelypteris glandulosolanosa (Raqui-Raqui): Preliminary Characterization and Anticancer Activity

et al. 2022

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“…Nanoparticles (NPs) have emerged as a novel vehicle for the targeted delivery of drugs, vaccines, bioimaging, and enhanced bioavailability. Because of its unique features of water solubility, biocompatibility, cost-effective manufacturing, and low toxicity, NPs are the preferred carrier ( Dheyab et al, 2021 ; Mohammadzadeh et al, 2022 ; Prajapati et al, 2019 ). Due to their structural similarities, synthetic NPs can precisely imitate the virus and interface extensively with its proteins.…”

Section: Pharmaceutical Product Developments For Immunity-boosting Ag...mentioning

confidence: 99%

An exhaustive comprehension of the role of herbal medicines in Pre- and Post-COVID manifestations

Prajapati¹,

Malaiya²,

Mishra³

et al. 2022

Journal of Ethnopharmacology

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“…[ 200 ] Therefore, determining the interaction of nanoparticles from plants is necessary to understand the synthesis from different aspects and to have better strategies for addressing challenges and future prospects of their use in therapeutic and pharmacological applications for various diseases and types of cancer. [ 201 ]…”

Section: Fabrication and Application In Biomedical Engineeringmentioning

confidence: 99%

Plant‐Actuated Micro–Nanorobotics Platforms: Structural Designs, Functional Prospects, and Biomedical Applications

Luthfikasari

Patil

Patel

et al. 2022

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Plants are anatomically and physiologically different from humans and animals; however, there are several possibilities to utilize the unique structures and physiological systems of plants and adapt them to new emerging technologies through a strategic biomimetic approach. Moreover, plants provide safe and sustainable results that can potentially solve the problem of mass‐producing practical materials with hazardous and toxic side effects, particularly in the biomedical field, which requires high biocompatibility. In this review, it is investigated how micro–nanostructures available in plants (e.g., nanoparticles, nanofibers and their composites, nanoporous materials, and natural micromotors) are adapted and utilized in the design of suitable materials for a micro–nanorobot platform. How plants’ work on micro‐ and nanoscale systems (e.g., surface roughness, osmotically induced movements such as nastic and tropic, and energy conversion and harvesting) that are unique to plants, can provide functionality on the platform and become further prospective resources are examined. Furthermore, implementation across organisms and fields, which is promising for future practical applications of the plant‐actuated micro–nanorobot platform, especially on biomedical applications, is discussed. Finally, the challenges following its implementation in the micro–nanorobot platform are also presented to provide advanced adaptation in the future.

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Applications of plant-based nanoparticles in nanomedicine: A review

Cited by 82 publications

References 161 publications

Green Synthesis of a Novel Silver Nanoparticle Conjugated with Thelypteris glandulosolanosa (Raqui-Raqui): Preliminary Characterization and Anticancer Activity

Green Synthesis of a Novel Silver Nanoparticle Conjugated with Thelypteris glandulosolanosa (Raqui-Raqui): Preliminary Characterization and Anticancer Activity

An exhaustive comprehension of the role of herbal medicines in Pre- and Post-COVID manifestations

Plant‐Actuated Micro–Nanorobotics Platforms: Structural Designs, Functional Prospects, and Biomedical Applications

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