Applications of biometrics, histometrics and cytometrics in deep learning

Tjahyadi, David; Parwanto, ML Edy

doi:10.15562/bmj.v11i2.3265

Cited by 2 publications

(1 citation statement)

References 17 publications

(19 reference statements)

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“…(34) The term histometrics is used for identification and authentication based on unique biological characteristics at the tissue level. (35) Research focusing on histometrics has been carried out, and the data are expressed quantitatively. (36) In our study, in contrast with previous studies, we evaluated the effect of filtered kretek cigarettes at doses of 1 stick/day or 2 sticks/day for 30 days on rat bronchial histometric measurements.…”

Section: Introductionmentioning

confidence: 99%

Effects of low-dose filtered kretek cigarette smoke on bronchial smooth muscle in male Sprague-Dawley rats

Tjahyadi,

Parwanto,

Sisca

et al. 2023

Univ Med

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BackgroundKretek cigarettes contain less nicotine and tar than conventional cigarettes. Exposure to cigarette smoke occurs mainly in the respiratory tract, resulting in histometric changes. The aim of this study was to evaluate the effect of filtered kretek cigarette smoke on bronchial histometric measurements in male Sprague-Dawley rats. MethodsAn experimental laboratory study was conducted involving 18 male Sprague-Dawley rats, aged 2-3 months, ranging from 150 to 250 grams in body weight. They were randomized into group 1 (controls) and experimental groups 2 and 3. Group 2 was exposed to filtered cigarette smoke at a dose of 1 stick/day and group 3 to 2 sticks/day. Treatment time for all groups was 30 days. Observation of bronchial histometric measurements of the lumen include, length, width, area, and perimeter. In addition, the bronchial mucosal and smooth muscle layers were also measured. The one way-ANOVA test was used to analyze the data. ResultsThe mean area and mean perimeter of the bronchial lumen of the rats were significantly greater in group 1 than in groups 2 and 3 (p=0.000). The mean bronchial smooth muscle area of the rats in group 1 was smaller than the mean in group 2, which was in turn smaller than the mean in group 3 (p=0.000). Apparently the rats in the treatment groups had undergone bronchoconstriction. ConclusionExposure to filtered kretek cigarette smoke at a dose of 1 stick/day as well as 2 sticks/day for 30 days caused bronchial mucosal hyperplasia and bronchoconstriction in male rats.

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Section: Introductionmentioning

confidence: 99%

Effects of low-dose filtered kretek cigarette smoke on bronchial smooth muscle in male Sprague-Dawley rats

Tjahyadi,

Parwanto,

Sisca

et al. 2023

Univ Med

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Decreased density of pyramidal cells in the cerebral cortex, and Purkinje cells in the cerebellar cortex of Sprague-Dawley rats after being exposed to filtered kretek cigarette smoke

et al. 2023

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Filtered kretek cigarette smoke is a gas that contains solid components (particulates). Carcinogenic chemicals are present in this type of cigarette smoke. Furthermore, it is said that tobacco has a major negative impact on cerebral structure development, creates addiction, and alters brain activity and function. The purpose of this study was to see how filtered kretek cigarette smoke affected the density of pyramidal cells in the cerebral cortex and Purkinje cells in the cerebellar cortex. An experimental and control group design was used for the study. Group 1 (6 rats) is the control group, and the rats breathe normally. Group 2 (6 rats) was exposed to filtered kretek cigarette smoke at a rate of one stick per day for three months. Pyramidal cells in the rat cerebral cortex and Purkinje cells in the cerebellar cortex were studied. Pyramidal cells were expected to be distributed in the cerebral cortex at the hippocampus area of rats in group 1. In contrast, the density of pyramidal cells decreased in group 2. The number of pyramidal cells in the rat cerebral cortex differed significantly between groups 1 and 2 (p<0.001). Purkinje cells in the cerebellar cortex in group 1 were normal, whereas Purkinje cells in group 2 were degenerated. The distance between Purkinje cells in the cerebellar cortex was greater in group 1 than in group 2 (p<0.001). Rats exposed to 1 stick of Kretek cigarette smoke each day for 3 months had lower pyramidal cell density in the cerebral cortex and hippocampus. The same result happened: one stick of Kretek cigarette smoke each day for three months reduced Purkinje cell density in the cerebellar cortex.

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Applications of biometrics, histometrics and cytometrics in deep learning

Cited by 2 publications

References 17 publications

Effects of low-dose filtered kretek cigarette smoke on bronchial smooth muscle in male Sprague-Dawley rats

Effects of low-dose filtered kretek cigarette smoke on bronchial smooth muscle in male Sprague-Dawley rats

Decreased density of pyramidal cells in the cerebral cortex, and Purkinje cells in the cerebellar cortex of Sprague-Dawley rats after being exposed to filtered kretek cigarette smoke

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