Application of Texture and Fractal Dimension Analysis to Estimate Effectiveness of Oral Leukoplakia Treatment Using an Er:YAG Laser—A Prospective Study

Jurczyszyn, Kamil; Kozakiewicz, Marcin

doi:10.3390/ma13163614

Cited by 6 publications

(3 citation statements)

References 41 publications

(47 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this work, it was reported that the FD values increased as the age of the patients increased. Along the same lines, Jurczyszyne et al [ 37 ] reported that in OL patients treated with a LiteTouch™ Er: YAG dental laser, the FD in the photographic images increased significantly after laser treatment, allowing FD to be used as a control mechanism for the effectiveness of the treatment.…”

Section: Discussionmentioning

confidence: 91%

Use of the Fractal Dimension to Differentiate Epithelium and Connective Tissue in Oral Leukoplakias

Sánchez

García

Chamorro-Petronacci

et al. 2022

Cancers

View full text Add to dashboard Cite

Background: Oral leukoplakia (OL) is considered one of the most common potentially malignant oral disorders (OPMD), with a verified increased risk of developing oral cancer. The identification of the dysplasia grade (low–high) is the only consolidated factor used to evaluate this risk. The objective of this study was to verify the role of the fractal dimension (FD) in assessing this dysplasia. Methods: To begin, 29 OL and 10 normal oral mucosa (NOM) biopsies were retrieved for FD analysis of the epithelial (dime) and the connective (dimc) tissue. Results: In the OL group, the median value of dime is higher (1.67, IQR = 0.12) than for the NOM group (1.56, IQR = 0.08), with statistically significant differences (Wilcoxon test, p = 0.0031). There were no differences in relation to dimc. Significant differences were observed between the non-dysplasia vs. high-grade (p = 0.0156) and low-grade vs. high-grade (p = 0.0049) groups. No significant differences were identified in relation to dimc for the different degrees of dysplasia. For a cut-off point of 1.44 of dime, a specificity of 96.6% was obtained, a sensitivity of 100%, and an AUC = 0.819 (p = 0.003). Conclusions: FD at the level of the epithelium may be used as a diagnostic tool in OL.

show abstract

Section: Discussionmentioning

confidence: 91%

Use of the Fractal Dimension to Differentiate Epithelium and Connective Tissue in Oral Leukoplakias

Sánchez

García

Chamorro-Petronacci

et al. 2022

Cancers

View full text Add to dashboard Cite

show abstract

“…Converting a colour image to a single-bit image is a process in which some of the analysed details are lost. We showed that the FD of oral leukoplakia was significantly lower than that of healthy mucosa with no statistical differences between the treated lesion and healthy mucosa [ 36 ]. In the aforementioned study, the FD of the examined lesion was lower than that of the reference mucosa, and after treatment, it was close to that of the normal mucosa, as in our study.…”

Section: Discussionmentioning

confidence: 99%

Application of Fractal Dimension and Texture Analysis to Evaluate the Effectiveness of Treatment of a Venous Lake in the Oral Mucosa Using a 980 nm Diode Laser—A Preliminary Study

2021

Self Cite

View full text Add to dashboard Cite

Venous lake (VL) is a common lesion resulting from the enlargement of thin-walled veins surrounded by a thick wall of fibrous tissue. Photocoagulation is becoming one of the basic methods for treating small vascular lesions. The aim of this study was an application of texture analysis (TA) and fractal dimension analysis (FDA) to evaluate VL treatment. Twenty-three VLs were included in the study. We used a 980 nm diode laser, 6 W, 100 ms pulse mode with a 50% duty cycle. The total dose of energy was in a range from 80 J to 600 J. We used the difference of intensity algorithm for FDA and microcontrast and a co-occurrence matrix for TA. A complete therapeutic effect was achieved in 83%, and in 9%, scar formation was observed after three months. No healing was observed in 4%, and there was partial healing in 4%. No differences in FD were observed between the lesions after three months and the healthy mucosa. The fractal dimension and microcontrast of a vascular lesion are mutually coupled. FDA and TA is a useful and objective method of assessing treatment effects for venous lakes. The non-contact mode of the 980 nm diode laser is an effective and safe method for treating a VL.

show abstract

“…Although the present review focused on the diagnostic and prognostic value of fractal analysis in oral oncology, the literature reported some sporadic and preliminary works dealing with the monitoring of treatments as reported by the Polish group of Jurczyszyn et al [51,52], who applied fractal dimension and texture analysis of lesion autofluorescence in the evaluation of oral lichen planus treatment effectiveness and in estimating the effectiveness of oral leukoplakia treatment using the LiteTouch™ Er:YAG Dental laser, or by Varsha et al, who recently explored the pre-and post-treatment objective evaluation of remission in oral lichen planus using fractal analysis and compared it with the visual analog (VAS) scale [53].…”

Section: Future Directionsmentioning

confidence: 99%

Fractal Analysis Applied to the Diagnosis of Oral Cancer and Oral Potentially Malignant Disorders: A Comprehensive Review

Contaldo,

Di Spirito,

Di Palo

et al. 2024

Applied Sciences

View full text Add to dashboard Cite

In nature, everything is regular and orderly arranged. The degree of derailment from geometry is related to the disarrangement of living tissues associated with diseases. In the diagnostic field, fractal analysis calculates the fractal dimension (FD), a numerical measure of the degree of regularity of a tissue or structure. As for oral lesions, fractal analysis has been reported to determine the degree of irregular tissue/vascularization derailment mathematically, and this event has been correlated with the nature of the lesion. The purpose of this paper is to evaluate the scientific literature on the fractal analysis of oral cancer and its precursors (oral potentially malignant disorders, OPMDs) to convey whether the specific fractal dimension may be predictive of cancer or the cancerous progression of OPMDs. For this purpose, three databases (PubMed, Scopus, and ISI Web of Science) were investigated according to the PRISMA checklist to answer the following query: “Is fractal analysis a support method to diagnose oral cancer and distinguish it from its precursors?” The risk of biases was also assessed. All original articles published in English were considered; letters, reviews, editorials, and proceedings were excluded.

show abstract

Application of Texture and Fractal Dimension Analysis to Estimate Effectiveness of Oral Leukoplakia Treatment Using an Er:YAG Laser—A Prospective Study

Cited by 6 publications

References 41 publications

Use of the Fractal Dimension to Differentiate Epithelium and Connective Tissue in Oral Leukoplakias

Use of the Fractal Dimension to Differentiate Epithelium and Connective Tissue in Oral Leukoplakias

Application of Fractal Dimension and Texture Analysis to Evaluate the Effectiveness of Treatment of a Venous Lake in the Oral Mucosa Using a 980 nm Diode Laser—A Preliminary Study

Fractal Analysis Applied to the Diagnosis of Oral Cancer and Oral Potentially Malignant Disorders: A Comprehensive Review

Contact Info

Product

Resources

About