“…2B), the need for a sterile or non-sterile process, general process control and up-scaling can put restraints on the reactor design , Durand 2003. In contrast, cultivation of mixed organisms is more easily Table 1 Properties of bioreactor types used in SSF (Cen & Xia 1999, Durand 2003, Rodríguez Couto & Sanromán 2006b; compare also Fig. 2B Damage to the inoculum through sheer forces feasible in SSF which can be of advantage in production of enzyme mixtures and increasing absolute yields (Hölker et al 2004;see below).…”