Application of Nanomaterials for Coping with Mycotoxin Contamination in Food Safety: From Detection to Control

Lin, Xianfeng; Yu, Wenyan; Tong, Xinyu; Li, Changxin; Duan, Nuo; Wang, Zhouping; Wu, Shijia

doi:10.1080/10408347.2022.2076063

Cited by 20 publications

(9 citation statements)

References 264 publications

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“…Nevertheless, some challenges or limitations are yet to be solved. The background fluorescence and complex matrix components of the tested samples may interfere the fluorescence signals [ 55 ]. Moreover, the corresponding antibody of multiple mycotoxins need to be prepared for simultaneous detection.…”

Section: Advance Multi-mycotoxin Immuno-based Analysismentioning

confidence: 99%

Recent advances in immunoassay-based mycotoxin analysis and toxicogenomic technologies

Liew¹,

Sabran²

2022

Journal of Food and Drug Analysis

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The co-occurrence and accumulation of mycotoxin in food and feed constitutes a major issue to food safety, food security, and public health. Accurate and sensitive mycotoxins analysis can avoid toxin contamination as well as reduce food wastage caused by false positive results. This mini review focuses on the recent advance in detection methods for multiple mycotoxins, which mainly depends on immunoassay technologies. Advance immunoassay technologies integrated in mycotoxin analysis enable simultaneous detection of multiple mycotoxins and enhance the outcomes’ quality. It highlights toxicogenomic as novel approach for hazard assessment by utilizing computational methods to map molecular events and biological processes. Indeed, toxicogenomic is a powerful tool to understand health effects from mycotoxin exposure as it offers insight on the mechanisms by which mycotoxins exposures cause diseases.

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Section: Advance Multi-mycotoxin Immuno-based Analysismentioning

confidence: 99%

Recent advances in immunoassay-based mycotoxin analysis and toxicogenomic technologies

Liew¹,

Sabran²

2022

Journal of Food and Drug Analysis

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“…Even low doses of mycotoxins can cause cancer, liver disease, and death in humans. Therefore, mycotoxin detection is vital for human health [ 92 ]. Due to the flexible structure of LMOFs, multiple fluorescent centers can interact with one another to adjust fluorescence and generate new dual emissions for radiometric sensors.…”

Section: Optical Sensing Platforms For Sensing Different Mycotoxins I...mentioning

confidence: 99%

MOF-Based Mycotoxin Nanosensors for Food Quality and Safety Assessment through Electrochemical and Optical Methods

et al. 2022

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Mycotoxins in food are hazardous for animal and human health, resulting in food waste and exacerbating the critical global food security situation. In addition, they affect commerce, particularly the incomes of rural farmers. The grave consequences of these contaminants require a comprehensive strategy for their elimination to preserve consumer safety and regulatory compliance. Therefore, developing a policy framework and control strategy for these contaminants is essential to improve food safety. In this context, sensing approaches based on metal-organic frameworks (MOF) offer a unique tool for the quick and effective detection of pathogenic microorganisms, heavy metals, prohibited food additives, persistent organic pollutants (POPs), toxins, veterinary medications, and pesticide residues. This review focuses on the rapid screening of MOF-based sensors to examine food safety by describing the main features and characteristics of MOF-based nanocomposites. In addition, the main prospects of MOF-based sensors are highlighted in this paper. MOF-based sensing approaches can be advantageous for assessing food safety owing to their mobility, affordability, dependability, sensitivity, and stability. We believe this report will assist readers in comprehending the impacts of food jeopardy exposure, the implications on health, and the usage of metal-organic frameworks for detecting and sensing nourishment risks.

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“…As one of the most toxic mycotoxins, aflatoxin B 1 (AFB 1 ) produced by Aspergillus is highly carcinogenic and can cause serious adverse effects on public health. 21,22 Because of its high thermal and chemical stability, AFB 1 is also difficult to remove during general processing. 22,23 Therefore, the sensitive detection and efficient removal of AFB 1 are of great significance in safeguarding food security and human health.…”

Section: Introductionmentioning

confidence: 99%

Fe–Co-Based Metal–Organic Frameworks as Peroxidase Mimics for Sensitive Colorimetric Detection and Efficient Degradation of Aflatoxin B₁

Lin,

Li,

et al. 2024

ACS Appl. Mater. Interfaces

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Building multifunctional platforms for integrating the detection and control of hazards has great significance in food safety and environment protection. Herein, bimetallic Fe−Cobased metal−organic frameworks (Fe−Co-MOFs) peroxidase mimics are prepared and applied to develop a bifunctional platform for the synergetic sensitive detection and controllable degradation of aflatoxin B 1 (AFB 1 ). On the one hand, Fe−Co-MOFs with excellent peroxidase-like activity are combined with target-induced catalyzed hairpin assembly (CHA) to construct a colorimetric aptasensor for the detection of AFB 1 . Specifically, the binding of aptamer with AFB 1 releases the prelocked Trigger to initiate the CHA cycle between hairpin H2-modified Fe−Co-MOFs and hairpin H1-tethered magnetic nanoparticles to form complexes. After magnetic separation, the colorimetric signal of the supernatant in the presence of TMB and H 2 O 2 is inversely proportional to the target contents. Under optimal conditions, this biosensor enables the analysis of AFB 1 with a limit of detection of 6.44 pg/mL, and high selectivity and satisfactory recovery in real samples are obtained. On the other hand, Fe−Co-MOFs with remarkable Fenton-like catalytic degradation performance for organic contaminants are further used for the detoxification of AFB 1 after colorimetric detection. The AFB 1 is almost completely removed within 120 min. Overall, the introduction of CHA improves the sensing sensitivity; efficient postcolorimetric-detection degradation of AFB 1 reduces the secondary contamination and risk to the experimental environment and operators. This strategy is expected to provide ideas for designing other multifunctional platforms to integrate the detection and degradation of various hazards.

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Application of Nanomaterials for Coping with Mycotoxin Contamination in Food Safety: From Detection to Control

Cited by 20 publications

References 264 publications

Recent advances in immunoassay-based mycotoxin analysis and toxicogenomic technologies

Recent advances in immunoassay-based mycotoxin analysis and toxicogenomic technologies

MOF-Based Mycotoxin Nanosensors for Food Quality and Safety Assessment through Electrochemical and Optical Methods

Fe–Co-Based Metal–Organic Frameworks as Peroxidase Mimics for Sensitive Colorimetric Detection and Efficient Degradation of Aflatoxin B₁

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Application of Nanomaterials for Coping with Mycotoxin Contamination in Food Safety: From Detection to Control

Cited by 20 publications

References 264 publications

Recent advances in immunoassay-based mycotoxin analysis and toxicogenomic technologies

Recent advances in immunoassay-based mycotoxin analysis and toxicogenomic technologies

MOF-Based Mycotoxin Nanosensors for Food Quality and Safety Assessment through Electrochemical and Optical Methods

Fe–Co-Based Metal–Organic Frameworks as Peroxidase Mimics for Sensitive Colorimetric Detection and Efficient Degradation of Aflatoxin B1

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Product

Resources

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Fe–Co-Based Metal–Organic Frameworks as Peroxidase Mimics for Sensitive Colorimetric Detection and Efficient Degradation of Aflatoxin B₁