MOF-Based Mycotoxin Nanosensors for Food Quality and Safety Assessment through Electrochemical and Optical Methods

Abstract

Mycotoxins in food are hazardous for animal and human health, resulting in food waste and exacerbating the critical global food security situation. In addition, they affect commerce, particularly the incomes of rural farmers. The grave consequences of these contaminants require a comprehensive strategy for their elimination to preserve consumer safety and regulatory compliance. Therefore, developing a policy framework and control strategy for these contaminants is essential to improve food safety. In this context, sensing approaches based on metal-organic frameworks (MOF) offer a unique tool for the quick and effective detection of pathogenic microorganisms, heavy metals, prohibited food additives, persistent organic pollutants (POPs), toxins, veterinary medications, and pesticide residues. This review focuses on the rapid screening of MOF-based sensors to examine food safety by describing the main features and characteristics of MOF-based nanocomposites. In addition, the main prospects of MOF-based sensors are highlighted in this paper. MOF-based sensing approaches can be advantageous for assessing food safety owing to their mobility, affordability, dependability, sensitivity, and stability. We believe this report will assist readers in comprehending the impacts of food jeopardy exposure, the implications on health, and the usage of metal-organic frameworks for detecting and sensing nourishment risks.

Research Progress on Electrochemical Sensors based on Metal-Organic Framework Materials for the Detection of Mycotoxins in Food

“…Due to their ordered porous structure, high porosity, adjustable specific surface area, and high affinity, MOF has been proven to be promising materials for the detection of fungal toxins in food. [15] The high surface area of MOF can concentrate fungal toxins, thereby increasing the sensitivity of fungal toxin detection; specific functional sites can achieve the specific recognition of fungal toxins through host-guest interactions; high porosity is advantageous for adsorbing a large number of molecules to be tested, strong adsorptivity, improving detection efficiency. [16] Although MOF is an ideal material for modifying electrode surfaces, its poor conductivity and mechanical properties prevent them from being used directly as electrode materials.…”

An Ultrasensitive miRNA-Based Genosensor for Detection of MicroRNA 21 in Gastric Cancer Cells Based on Functional Signal Amplifier and Synthesized Perovskite-Graphene Oxide and AuNPs

“…Sensing assays have attracted much attention due to fast, selective, sensitive, and low-cost analytical devices, including two elements of biological recognition element for capturing target and converter miRNAs detection reaction signal into a measurable signal [27,28]. Based on the type of transducers, biosensors can be classified into several major groups, including optical, thermal, piezoelectric, and electrochemical sensors [29,30].…”

Sensitive nanobiosensor for miR-155 detection using a novel nanocomposite of carbon nanofiber, metal-organic framework, and two quantum dots

“…Due to their unique properties, such as structural and functional tunability, these hybrid nano-porous materials have become suitable candidates for various applications, including heterogeneous catalysis, sensing, energy harvesting, gas absorption, and biosensors [33][34][35][36][37]. They also support loading nanoparticles [38][39][40][41]. Furthermore, the MOFs can be chemically modified to enhance their specific functions, enabling them to promote several technological advancements, especially biosensors.…”