Application of Metal Implant 16-Bit Imaging: New Technique in Radiotherapy

Ni, Xinye; Gao, Liugang; Fang, Mingming; Lin, Tao

doi:10.1177/1533034616649530

Cited by 5 publications

(8 citation statements)

References 8 publications

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“…CT–ED conversion curve of 16-bit depth shows a lower dose compared to the 12-bit and 12-bit extended. The result supported by the Xin-ye (2017) where the dose at downstream of titanium and stainless steel in 12-bit was 15·9%, and 42·7% higher than 16-bit depth 7 . However, current results (Figure 7) show the new CT–ED conversion curve in TPS reduced the radiation dose variation among 12-bit, 12-bit extended and 16-bit depths.…”

Section: Discussionmentioning

confidence: 56%

“…The result supported by the Xin-ye (2017) where the dose at downstream of titanium and stainless steel in 12-bit was 15•9%, and 42•7% higher than 16-bit depth. 7 However, current results (Figure 7) show the new CT-ED conversion curve in TPS reduced the radiation dose variation among 12-bit, 12-bit extended and 16-bit depths. Thus, CT-ED conversion curve needs to be updated in the TPS system to provide accurate dose calculation.…”

Section: Discussionmentioning

confidence: 70%

“…– 5 Inaccuracies in the HU values result in an error in ED or stopping power estimate, which may essentially influence the dose calculation and optimisation processes 6 . Thus, the presence of medical implants results in inaccurate dosimetry calculations when assessing tumour versus normal tissue 7 . Furthermore, the AAPM Report No.…”

Section: Introductionmentioning

confidence: 99%

“…6 Thus, the presence of medical implants results in inaccurate dosimetry calculations when assessing tumour versus normal tissue. 7 Furthermore, the AAPM Report No. 85 emphasised the need to develop and implement tissue inhomogeneity corrections.…”

Section: Introductionmentioning

confidence: 99%

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Determination of computed tomography number of high-density materials in 12-bit, 12-bit extended and 16-bit depth for dosimetric calculation in treatment planning system

et al. 2019

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AimThe main aim was to examine the effect of bit depth on computed tomography (CT) number for high-density materials. Analysis of the CT number for high-density materials using 16-bit scanners will extend the CT scale that currently exists for 12-bit scanners and thus will be beneficial for use in CT–electron density (ED) curve in radiotherapy treatment planning system (TPS). Implementation of this extended CT scale will compensate for tissue heterogeneity during CT–ED conversion in treatment planning.Materials and methodsAn in-house built phantom with 10 different metal samples was scanned using 80, 100 and 120 kVp in two different CT scanners. A region of interest was set at the centre of the material and the mean CT numbers together with data deviation were determined. Dosimetry calculation was performed by applying a direct anterior beam on 12-bit, 12-bit extended and 16-bit.ResultsHigh-density materials (>4·34 g cm−3) in 16-bit depth provide disparities up to 44% compared to Siemens’ 12-bit extended. Influence of tube voltage showed a significant difference (p<0·05) in both bit depth and CT number of the gold and amalgam saturated in 16-bit depth. A 120 kVp energy illustrated a low variation on CT number for different scanners, but dosimetry calculation showed significant disparities at the metal interface in 12-bit, 12-bit extended and 16-bit.FindingsHigh-density materials require 16-bit scanners to obtain CT number to be implemented in treatment planning in radiotherapy. This also suggests that proper tube voltage together with correct CT–ED resulted in accurate TPS algorithm calculation.

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Section: Discussionmentioning

confidence: 56%

Section: Discussionmentioning

confidence: 70%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Determination of computed tomography number of high-density materials in 12-bit, 12-bit extended and 16-bit depth for dosimetric calculation in treatment planning system

et al. 2019

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“…Many investigators have observed the effects of the bit-depth and explored the dose distribution behind the metallic implants (Coolens & Childs, 2003;Mullins et al, 2016;Xin-ye et al, 2016). However, the results are not sufficient to conclude how the bit-depth influences radiotherapy dosimetry, especially for a full 16-bit depth scanner.…”

Section: Introductionmentioning

confidence: 99%

Dosimetric Comparison between Monaco TPS and EGSnrc Monte Carlo simulation on Titanium Rod in 12bit and 16bit Image Format

Jayamani

Osman

Tajuddin

et al. 2020

Journal of Radiation Research and Applied Sciences

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This study purpose is to investigate the effects of using different bit depth DICOM images for the 6 MV photon beam on a titanium rod. An EGSnrc Monte Carlo simulation on the Elekta Synergy LINAC executed as a dosimetry comparison tool for the TPS. CT scanners with 12-bit, 12-bit extended (Siemens Somatom Definition AS) and 16-bit depth (Toshiba Aquilion) parameters were applied to scan a wax phantom with a titanium rod. A direct beam (AP) with a field size of 10 x 10 cm2 was prescribed 200 cGy dose and was planned on the MONACO TPS. The TPS outcome was compared with the validated LINAC EGSnrc calculation. The downstream dose of the titanium rod was analyzed for each bit-depth parameters and the limitations of the existing TPS were examined. CT numbers of the titanium rod vary for each bit-depth parameter, where 3071 ± 0 HU, 8513 ± 31 HU, and 10006 ± 73 HU for 12-bit, 12-bit extended, and 16-bit images, respectively. The 16-bit depth scanner gives the most accurate CT number of the titanium rod with the correct dose calculation while, the Monaco TPS underestimates the real titanium rod dose compared to the EGSnrc calculations by 4.95%.

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Effects of peripherally inserted central catheter on dosimetry of the blood vessel region in volumetric modulated arc therapy planning for lung cancer

Zhao

et al. 2021

Precision Radiation Oncology

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Objective: A peripherally inserted central catheter (PICC) is a safe and effective drug delivery method of chemoradiotherapy for lung cancer. However, the risk of vascular damage to patients who require PICC implantation during radiotherapy may be increased. This study compared dosimetry differences in the blood vessel region, as well as the planning target volume and other organs at risk between two volumetric modulated arc therapy plans with and without a PICC for lung cancer. The aim of which was to provide guidance for clinicians to select the proper PICC implantation time.Methods: A total of 10 male patients with PICCs who received chemoradiotherapy for lung cancer in Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center between 1 January 2019 and 30 November 2019 were included. The prescription dose was 50 Gy in 25 fractions. Two volumetric modulated arc therapy plans, with and without a PICC, were designed for each selected patient on a Varian Eclipse 13.6™ planning system. Statistical analysis of the blood vessel dose distribution of the PICC region and the target dose distribution, including the homogeneity index and conformity index, as well as irradiation doses to the lungs, heart, esophagus, and spinal cord, was carried out for the two groups and the differences were compared.Results: When comparing the two plans, the mean dose (D mean ) of the PICC region for the plan with PICC was lower than that for the plan without(P = 0.01). The conformity index of the target, the maximum dose (D max ) and minimum dose (D min ) of the blood vessel of the PICC region, ranged from 2 to 20% in both groups, with no significant difference (conformity index: P = 0.87, D max : P = 0.81, D min : P = 0.83). There was no statistically significant difference in the D 2% (P = 0.34) and D 98% (P = 0.30) of the target, V 20% (P = 0.34) and V 30% (P = 0.34) of the heart, D max (P > 0.05) and D min (P > 0.05) of the esophagus, V 5% (P = 0.34), V 20% (P = 0.33), V 30% (P = 0.17), and D mean (P = 0.33) of the lungs, and D max (P = 0.34) of the spinal cord between the two groups of plans.This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Application of Metal Implant 16-Bit Imaging: New Technique in Radiotherapy

Abstract: A 16-bit imaging technology of metal implants can distinguish the computed tomography value of different metal materials. Furthermore, the revised 16-bit imaging technology can improve the dose computational accuracy of radiotherapy plan with high-density metal implants.

Cited by 5 publications

References 8 publications

Determination of computed tomography number of high-density materials in 12-bit, 12-bit extended and 16-bit depth for dosimetric calculation in treatment planning system

Determination of computed tomography number of high-density materials in 12-bit, 12-bit extended and 16-bit depth for dosimetric calculation in treatment planning system

Dosimetric Comparison between Monaco TPS and EGSnrc Monte Carlo simulation on Titanium Rod in 12bit and 16bit Image Format

Effects of peripherally inserted central catheter on dosimetry of the blood vessel region in volumetric modulated arc therapy planning for lung cancer

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