Application of ion-exchange cartridge clean-up in food analysis

Ito, Yûko; Ikai, Yoshitomo; Oka, Hisao; Matsumoto, Hiroshi; Miyazaki, Yutaka; Takeba, Kazue; Nagase, Hisamitsu

doi:10.1016/s0021-9673(01)00512-x

Cited by 34 publications

(14 citation statements)

References 13 publications

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“…Hence, it is common to analyse diaminopoyrimidines together with SA [276][277][278][279][280][281]. Recent review papers by Wang et al [10] and Samanidou et al [318] provide an excellent overview of SAs in foodstuff of animal origin.…”

Section: Sulphonamidesmentioning

confidence: 99%

Current trends in sample preparation for growth promoter and veterinary drug residue analysis

Kinsella

O’Mahony

Malone

et al. 2009

Journal of Chromatography A

181

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A comprehensive review is presented on the current trends in sample preparation for isolation of veterinary drugs and growth promotors from foods. The objective of the review is to firstly give an overview of the sample preparation techniques that are applied in field. The review will focus on new techniques and technologies, which improve efficiency and coverage of residues. The underlying theme to the paper is the developments that have been made in multi-residue methods and particularly multi-class methods for residues of licensed animal health products, which have been developed in the last couple of years. The role of multi-class methods is discussed and how they can be accommodated in future residue surveillance.

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Section: Sulphonamidesmentioning

confidence: 99%

Current trends in sample preparation for growth promoter and veterinary drug residue analysis

Kinsella

O’Mahony

Malone

et al. 2009

Journal of Chromatography A

181

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“…Octadecyl (C18)-bonded silica is the most widely employed SPE sorbent [37][38][39][40], although other solid phase materials such as LiChrolut EN [41], Isolut ENV1 [42,43] and even weak cation- [3], and strong anionexchangers [44] have also been reported in the literature for this purpose. The elution of the antibiotics retained by these sorbents is usually performed with aqueous methanol or ACN in some cases modified with a buffer.…”

Section: Factors Affecting Spe Preconcentration Of â-Lactam Antibioticsmentioning

confidence: 99%

Use of SDS micelles for improving sensitivity, resolution, and speed in the analysis of β‐lactam antibiotics in environmental waters by SPE and CE

Serrano

Silva

2007

Electrophoresis

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This study dealt with the potential of MEKC with LIF detection involving derivatization with sulfoindocyanine succinimidyl ester (Cy5) for the separation and determination of beta-lactam antibiotics (ampicillin, amoxicillin, cephradine, and cephalexin) in environmental water samples. Water samples of 50 mL were enriched by SPE by passage through a weak base-cation Amberlite(R) IRA-93 exchange column. SDS micelles play important roles in the whole analytical process by improving the yield (sensitivity) and the kinetics of the labeling reaction, the elution of the retained antibiotics from the SPE preconcentration system and the electrophoretic resolution of their Cy5-derivatives. The optimum procedure includes a derivatization step of the antibiotics at 25 degrees C for 10 min and direct injection for MEKC analysis, which is conducted within about 15 min using 15 mM SDS in the running buffer (35 mM sodium borate at pH 9.3). LODs from 30 to 45 ng/L and RSDs (within-day precision) from 3.5 to 5.9% were obtained for the antibiotics in water samples with average recoveries ranging from 96.4 to 99.4%. These results indicate that the method proposed is a straightforward and sensitive tool for the determination of these antibiotics in environmental water samples providing similar quantitative results to those using more expensive equipment like LC-electrospray MS/MS.

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“…The sample solution was prepared according to our previous method [10], except for using a mixed I.S. aqueous solution (0.25 g/ml each of PCG-d5 and NFPC-d6).…”

Section: Sample Preparationsmentioning

confidence: 99%

“…In our previous studies [10][11][12][13], we have reported the applicability of sample clean-up by an ion-exchange cartridge in combination with ion-pair HPLC for the analysis of ionable compounds in foods. Using this technique, we have already developed a confirmation method for six cationic penicillins, PCG, PCV, oxacillin (MPIPC), cloxacillin (MCIPC), NFPC and dicloxacillin (MDIPC), in bovine tissues by electrospray ionization liquid chromatography-tandem mass spectrometry (LC-ESI MS/MS) [10].…”

Section: Introductionmentioning

confidence: 99%

“…Using this technique, we have already developed a confirmation method for six cationic penicillins, PCG, PCV, oxacillin (MPIPC), cloxacillin (MCIPC), NFPC and dicloxacillin (MDIPC), in bovine tissues by electrospray ionization liquid chromatography-tandem mass spectrometry (LC-ESI MS/MS) [10]. Because of their effective clean-up and satisfactory separation, it can remove the influence of sample matrix on the MS response.…”

Section: Introductionmentioning

confidence: 99%

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