Application of Gafchromic EBT2 film for intraoperative radiation therapy quality assurance

Robatjazi, Mostafa; Mahdavi, Seied Rabi; Takavr, Abbas; Baghani, Hamid Reza

doi:10.1016/j.ejmp.2015.01.020

Cited by 28 publications

(27 citation statements)

References 13 publications

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“…12,19 In the range of 5-10 Gy, the response gradients are similar in the red and green channels. 12,19 The green channel was chosen to analyze the in vivo measurements, because the D s was expected to be $8.7 Gy. Solid phantoms were irradiated with lower doses (D s approximately 3 Gy); so, the analysis was performed using the red channel.…”

Section: Film Calibration and Read-outmentioning

confidence: 80%

“…In the International Society of Intraoperative Radiation Therapy database, the 6-cm applicator was most frequently used (33%), followed by the 5-cm applicator (28%) and 7-cm applicator (26%), and the 45°bevel applicator was used in 83% of pelvic IOERT procedures. 3 Analysis of the data summarized in Other authors reported good agreement (within 610%) between expected and measured doses for in vivo measurements performed with films during breast [10][11][12] and prostate 13 IOERT. However, in breast IOERT, the irradiation surface is usually flat, the radiation oncologist can visually assess the position of the film and non-bevelled applicators are most frequently used.…”

Section: Discussionmentioning

confidence: 99%

“…14 Film pixel value was converted into net optical density (netOD) using single-channel analysis. Following Robatjazi et al, 12 the colour channel with the greatest response gradient was used: this is the red channel below 5 Gy and the green channel above 10 Gy. 12,19 In the range of 5-10 Gy, the response gradients are similar in the red and green channels.…”

Section: Film Calibration and Read-outmentioning

confidence: 99%

“…Following Robatjazi et al, 12 the colour channel with the greatest response gradient was used: this is the red channel below 5 Gy and the green channel above 10 Gy. 12,19 In the range of 5-10 Gy, the response gradients are similar in the red and green channels. 12,19 The green channel was chosen to analyze the in vivo measurements, because the D s was expected to be $8.7 Gy.…”

Section: Film Calibration and Read-outmentioning

confidence: 99%

“…5,9 Good results have also been reported by authors using films for in vivo dosimetry during breast IOERT. [10][11][12] These studies were performed with mobile LINACs specific for IOERT, such as Novac7, Liac and Mobetron. A detailed study with MOSFETS was reported for IOERT of recurrent prostate cancer, where applicators with 4-5-cm diameter and 22.5°bevel were used.…”

Section: Introductionmentioning

confidence: 99%

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In vivodosimetry using Gafchromic films during pelvic intraoperative electron radiation therapy (IOERT)

Costa¹,

Sarmento²,

Gomes³

et al. 2016

BJR

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Objective: To characterize in vivo dose distributions during pelvic intraoperative electron radiation therapy (IOERT) for rectal cancer and to assess the alterations introduced by irregular irradiation surfaces in the presence of bevelled applicators. Methods: In vivo measurements were performed with Gafchromic films during 32 IOERT procedures. 1 film per procedure was used for the first 20 procedures. The methodology was then optimized for the remaining 12 procedures by using a set of 3 films. Both the average dose and two-dimensional dose distributions for each film were determined. Phantom measurements were performed for comparison. Results: For flat and concave surfaces, the doses measured in vivo agree with expected values. For concave surfaces with step-like irregularities, measured doses tend to be higher than expected doses. Results obtained with three films per procedure show a large variability along the irradiated surface, with important differences from expected profiles. These results are consistent with the presence of surface hotspots, such as those observed in phantoms in the presence of step-like irregularities, as well as fluid build-up. Conclusion: Clinical dose distributions in the IOERT of rectal cancer are often different from the references used for prescription. Further studies are necessary to assess the impact of these differences on treatment outcomes. In vivo measurements are important, but need to be accompanied by accurate imaging of positioning and irradiated surfaces. Advances in knowledge: These results confirm that surface irregularities occur frequently in rectal cancer IOERT and have a measurable effect on the dose distribution.

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Section: Film Calibration and Read-outmentioning

confidence: 80%

Section: Discussionmentioning

confidence: 99%

Section: Film Calibration and Read-outmentioning

confidence: 99%

Section: Film Calibration and Read-outmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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In vivodosimetry using Gafchromic films during pelvic intraoperative electron radiation therapy (IOERT)

Costa¹,

Sarmento²,

Gomes³

et al. 2016

BJR

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A virtual audit system for intensity‐modulated radiation therapy credentialing in Japan Clinical Oncology Group clinical trials: A pilot study

Nakamura

Zhou

Minemura³

et al. 2023

J Applied Clin Med Phys

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The Medical Physics Working Group of the Radiation Therapy Study Group at the Japan Clinical Oncology Group is currently developing a virtual audit system for intensity-modulated radiation therapy dosimetry credentialing. The target dosimeters include films and array detectors, such as ArcCHECK (Sun Nuclear Corporation, Melbourne, Florida, USA) and Delta4 (ScandiDos, Uppsala, Sweden). This pilot study investigated the feasibility of our virtual audit system using previously acquired data. Methods: We analyzed 46 films (32 and 14 in the axial and coronal planes, respectively) from 29 institutions. Global gamma analysis between measured and planned dose distributions used the following settings:3%/3 mm criteria (the dose denominator was 2 Gy), 30% threshold dose, no scaling of the datasets, and 90% tolerance level. In addition, 21 datasets from nine institutions were obtained for array evaluation. Five institutions used ArcCHECK, while the others used Delta4. Global gamma analysis was performed with 3%/2 mm criteria (the dose denominator was the maximum calculated dose), 10% threshold dose, and 95% tolerance level. The film calibration and gamma analysis were conducted with in-house software developed using Python (version 3.9.2). Results: The means ± standard deviations of the gamma passing rates were 99.4 ± 1.5% (range, 92.8%-100%) and 99.2 ± 1.0% (range, 97.0%-100%) in the film and array evaluations, respectively. Conclusion: This pilot study demonstrated the feasibility of virtual audits. The proposed virtual audit system will contribute to more efficient,cheaper,and more rapid trial credentialing than on-site and postal audits; however, the limitations should be considered when operating our virtual audit system.

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Effect of the solar irradiation on the structure and optical properties of Gafchromic films

et al. 2021

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Application of Gafchromic EBT2 film for intraoperative radiation therapy quality assurance

Cited by 28 publications

References 13 publications

In vivodosimetry using Gafchromic films during pelvic intraoperative electron radiation therapy (IOERT)

In vivodosimetry using Gafchromic films during pelvic intraoperative electron radiation therapy (IOERT)

A virtual audit system for intensity‐modulated radiation therapy credentialing in Japan Clinical Oncology Group clinical trials: A pilot study

Effect of the solar irradiation on the structure and optical properties of Gafchromic films

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