Application of CRISPR/Cas9-based genome editing in ecotoxicology

Zhao, Fang; Ding, Xiaofan; Liu, Zimeng; Yan, Xiao; Chen, Yanzhen; Jiang, Yaxin; Chen, Shunjie; Wang, Yuanfang; Kang, Tingting; Xie, Chun; He, Mian; Zheng, Jing

doi:10.1016/j.envpol.2023.122458

Cited by 5 publications

(2 citation statements)

References 191 publications

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“…This unique advantage enables engineers to create uncomplicated interfaces and molecular circuits, utilizing CRISPR's programmability to identify diverse targets, including proteins and nucleic acids [128]. CRISPR/Cas9, a cutting-edge genome-editing technology, has proven its efficacy in creating novel biological markers for distinct environmental contaminants [177].…”

Section: Environmental Monitoring Through the Use Of Biosensorsmentioning

confidence: 99%

Advances in Environmental Biotechnology with CRISPR/Cas9: Bibliometric Review and Cutting-Edge Applications

Verdezoto-Prado,

Chicaiza-Ortiz,

Mejía-Pérez

et al. 2024

Preprint

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CRISPR/Cas9 has emerged as the predominant method for genome editing due to its cost-effectiveness and broad applicability, playing a crucial role in advancing sustainable practices across various sectors. This systematic review leverages the PRISMA methodology to explore CRISPR/Cas9's impact on environmental protection, thereby supporting the Sustainable Development Goals (SDGs). Analyzing data from the Web of Science, the review found significant growth in related publications, with a 30% increase since 2014, predominantly from the US, China, Germany, and the UK. The study categorizes the scientific developments into three trends: advancements in agriculture, gene editing techniques, and biofuel production. Key discussions include the use of CRISPR/Cas9 in developing fourth-generation biofuels and environmental biosensors, as well as its applications in enhancing genetic resilience and controlling invasive species. These innovations highlight CRISPR/Cas9's potential in promoting sustainable resource management and energy generation, marking a pivotal contribution to ecological conservation and sustainability efforts.

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Section: Environmental Monitoring Through the Use Of Biosensorsmentioning

confidence: 99%

Advances in Environmental Biotechnology with CRISPR/Cas9: Bibliometric Review and Cutting-Edge Applications

Verdezoto-Prado,

Chicaiza-Ortiz,

Mejía-Pérez

et al. 2024

Preprint

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“…This may involve assessing changes in gene expression, protein levels, or cellular phenotypes (Zhao et al, 2023).…”

Section: Speciality Of Zebrafish Over Other Animal Model For Endocrin...mentioning

confidence: 99%

Swimming Through Science: Unveiling the Secrets of Endocrine Disruptors with Zebrafish Models

Bhapkar,

Umap,

Somkuwar

et al. 2024

COAS

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The utilization of zebrafish (Danio rerio) as a model organism in studying endocrine disruptor chemicals (EDCs) has emerged as a powerful and versatile approach in toxicology research. This review highlights the numerous advantages that make zebrafish an ideal model for assessing the impact of EDCs on endocrine systems. Zebrafish, with their high fecundity, transparent embryos and rapid development, offer a cost-effective and time-efficient platform for observing the effects of EDC exposure on various endocrine-related pathways. Furthermore, the zebrafish’s amenability to genetic manipulation has revolutionized the study of EDCs, allowing for precise control and modification of specific genes associated with endocrine function. Genetic application, such as transgenesis and CRISPR/Cas9 technology, enable researchers to create targeted mutants, providing valuable insights into the molecular mechanisms underlying endocrine disruption. This review underscores the pivotal role of zebrafish in advancing our understanding of EDCs, emphasizing the synergy between its inherent advantages and genetic tools, thus positioning it as a premier model for unraveling the complexities of endocrine disruption and facilitating the development of targeted interventions

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Scientific Advancement in Trait Measurement and Quantification

Maiti,

Joshi

2024

Plant Functional Traits for Improving Productivity

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Application of CRISPR/Cas9-based genome editing in ecotoxicology

Cited by 5 publications

References 191 publications

Advances in Environmental Biotechnology with CRISPR/Cas9: Bibliometric Review and Cutting-Edge Applications

Advances in Environmental Biotechnology with CRISPR/Cas9: Bibliometric Review and Cutting-Edge Applications

Swimming Through Science: Unveiling the Secrets of Endocrine Disruptors with Zebrafish Models

Scientific Advancement in Trait Measurement and Quantification

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