Application of Computer Simulation Results and Machine Learning in the Analysis of Microwave Radiothermometry Data

Abstract

This work was done with the aim of developing the fundamental breast cancer early differential diagnosis foundations based on modeling the spacetime temperature distribution using the microwave radiothermometry method and obtained data intelligent analysis. The article deals with the machine learning application in the microwave radiothermometry data analysis. The problems associated with the construction mammary glands temperature fields computer models for patients with various diagnostics classes, are also discussed. With the help of a computer experiment, based on the machine learning algorithms set (logistic regression, naive Bayesian classifier, support vector machine, decision tree, gradient boosting, Knearest neighbors, etc.) usage, the mammary glands temperature fields computer models set adequacy.

Improving the Efficiency of Oncological Diagnosis of the Breast Based on the Combined Use of Simulation Modeling and Artificial Intelligence Algorithms

“…See images of device in Figure 1) are basis of medical diagnostics of both diseases of breast [12,13] and other organs [4,8,56]. Our measurement data for temperature distributions for breast were obtained with this device, that provides an accuracy of about ±0.2 • C [32].…”

“…Mass-produced medical device RTM-01-RES with modifications (manufactured by RES, Ltd., Russia, Moscow [48], see images of device in Figure 1) is the basis of medical diagnostics of both diseases of the breast [12,13] and other organs [4,8,56]. Our measurement data for temperature distributions for breast were obtained with this device, which provides an accuracy of approximately ±0.2 • C [32].…”

“…It is important to emphasize that the electromagnetic characteristics of biological tissues depend on the frequency of microwave radiation. A detailed description of the numerical implementation of the mathematical model is discussed in the works [12,58].…”

“…Microwave thermometry is not limited to clinical practice and is used in pharmacology and physiological research to create thermal maps of muscles and internal organs in sports and health monitoring [55]. The MWR method has been successfully applied to the following organs, tissues, and diseases: 1-brain [7,25,43,56]; 2-breast [10,12,13,16]; 3-carotid arteries [49]; 4-venous diseases of the lower extremities [8]; 5-coronavirus infection (COVID-19) [4]; 6-arthritis of the large joints (elbow (6a), knee (6b), ankle (6c) [46,57], rheumatoid arthritic knee joints [11], sacroiliac joints [45]; 7-spine arthritis [58]; 8-acute inflammatory diseases of the prostate [42]; 9-kidney disease [42,59]; 10-cardiovascular diseases [50]; 11-bladder [59]; 12-pathology of the female reproductive system [54]; 13-diabetic foot ulceration pathology [60]; 14-thyroid [61].…”

“…Significant advances in the use of microwave radiometry are associated with the diagnosis of breast cancer [1,2,5,6,10,[12][13][14]. A positive outcome of breast cancer treatment is determined by the earliest possible diagnosis, covering a significant part of the population [15].…”