Application of atomic force microscopy methods for testing the surface parameters of coatings of medical implants

Abstract

Abstract-Atomic force microscopy methods are used to study calcium phosphate coatings that are formed on surfaces of various materials, which are used in medicine, by radio frequency magnetron sputtering of a hydroxyapatite target. The roughness parameters and values of the surface potentials of metal, polymer, and hybrid substrates are determined in a semicontact regime. Calcium phosphate coatings increase the roughness of surfaces of polymer and metal materials, thus presenting a stimu lating factor for the attachment and proliferation of osteogenic cells. Using the Kelvin method, it is shown that calcium phosphate coatings change the surface potential of substrates.

The formation of calcium phosphate coatings by pulse laser deposition on the surface of polymeric ferroelectric

“…Surface properties were also studied using the high resolution atomic force microscopy (AFM) using Solver-HV (NT-MDT). The topology and surface potential of the coatings were determined by the method described previously [39].…”

AFM Applications in Micro/Nanostructured Coatings

“…High accuracy, lack of any limitation in study of many surfaces in various medium conditions, lack of need for sample preparation in most cases, high measuring speed, development of 3D images, and potentials for the study of various surface features have made a growing interest for application of AFM in various fields of applied technology including aerospace, electronics, auto industry, material science, biology, telecommunication, energy, drug synthesis, cosmetics, petrochemistry, etc (84)(85)(86)(87)(88). Typically, the main reasons for application of AFM in various fields of technology are as follows:…”

“…Klimenov et al utilized AFM methods to examine calcium phosphate coatings developed on surfaces of various materials, which are used in medicine (86). They applied radio-frequency magnetron sputtering of a hydroxyapatite target.…”

Formation Hybrid Method of Multilayer Biocoatings, Based on PVD Technology

“…This, firstly, furthers to the intermediate calcium comprising phase's formation and then a hydroxyapatite layer which is stable in the organism environment. If using working gas Ar, formed coating surface is always has a positive potential, independently of the substrate type [19]. It is may be connected with the ions Ca 2+ high content in the coating.…”