The formation of calcium phosphate coatings by pulse laser deposition on the surface of polymeric ferroelectric

Abstract

This work analyses the properties of calcium phosphate coatings obtained by pulsed laser deposition on the surface of the ferroelectric polymer material. Atomic force and scanning electron microscopy studies demonstrate that, regardless of the type of sputtering target, the calcium phosphate coatings have a multiscale rough surface that is potentially capable of promoting the attachment and proliferation of osteoblasts. This developed surface of the coatings is due to its formation mainly from a liquid phase. The chemical and crystalline 2 composition of the coatings depends on the type of sputtering target used. It was shown that, regardless of the type of sputtering target, the crystalline structure of the ferroelectric polymer material does not change. Cell viability and adhesion studies of mesenchymal stromal cells on the coatings were conducted using flow cytometry and fluorescent microscopy. These studies indicated that the produced coatings are non-toxic.

In vitro Bioactivity, Bio-Corrosion Resistance and Antibacterial Property of Laser Cladded HA Coatings with Different Content of ZnO on Ti-6Al-4V Substrate

“…Different techniques, including Cathodic electro deposition (CED) 17 , sol-gel 18 , plasma-spraying 19 , and laser deposition 20 procedures have been developed. Of these methods, laser cladding (LC) has gained extensive use due to its ability to achieve appropriate surface textures and surface chemistry and thereby improve the biocompatibility of metallic surfaces at the tissue-implant interface [21][22][23] .…”

Interaction of Bioresorbable Composite Implants Made by Solution Blow Spinning With Tissues

“…Denis Evgen'evich KULBAKIN 1,2,3,4 , Evgeniy Lkhamatsyrenovich CHOYNZONOV 1,2,3,5 , Nadezhda Viktorovna CHERDYNTSEVA 1,4 , Evgeniy Nikolaevich BOLBASOV 5 , Valeriy Anatol'evich SVETLICHNYI 4 , Ivan Nikolaevich LAPIN 4 , Sergei Ivanovich TVERDOKHLEBOV 5 , Aleksandr Aleksandrovich ZHERAVIN 6 , Lyudmila Nikolaevna BONDAR 1 , Vladimir Mikhaylovich PERELMUTER 1 выполняют замену дефектов скелета и мягких тканей, однако не могут адекватно восстановить тонкую, сложную анатомию челюстно-лицевой области [7].…”

“…Для приготовления модельных имплантатов использовались следующие материалы: полимерная основа -по-лимолочная кислота PURASORB ® PL 38 («Purac», Нидерланды), наполнители -микронные гидроксиапатит (Ca 5 (PO 4 ) 3 (OH)) (Санкт-Петербургский филиал ФГУП «Экспериментальные производственные мастерские» ФМБА России -СКТБ Биофизприбор, Россия) и кальций фосфорнокислый двузамещенный водный (CaHPO 4 ) (КФК) («Sigma-Aldrich», США), растворитель -хлороформ (CHCl 3 ) («Экрос», Россия). Перед использованием исходные промышленные микронные порошки подвергались фрагментации методом импульсной лазерной абляции по методике, описанной в работе [2]. В результате высокоэнергетического импульсного лазерного воздействия в порошке появлялась нано-и субмикронная фракция, а также происходила модификация поверхности частиц.…”

Composite implants coated with biodegradable polymers prevent stimulating tumor progression

“…We have determined that the materials obtained via laser ablation of a dicalcium phosphate (CaHPO 4 ) solid target is not toxic and provides high adhesion of stem cells [6], which was the reason DCPD was chosen to be studied in terms of oncologic safety.…”