Application of Artificial Intelligence-Based Computation in the Health Sciences to Ward off the COVID-19 Pandemic

Parikesit, Arli Aditya; Ratnasari, Nanda Rizqia Pradana; Anurogo, Dito

doi:10.31344/ijhhs.v5i2.256

Cited by 5 publications

(3 citation statements)

References 50 publications

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“…Later by adapting the deep docking, QSAR etc., are using to identify the protein inhibitors from available databases like FDA approved drugs, ZINC database etc. In majority of studies 3CLPro of SARS-CoV-2 is target protein, Deep learning model and molecular dynamic simulation methods approched to finilise the highest hit compound to target protein like 3CLPro of SARS-CoV-2 42,44,[49][50][51][52][53] . Some of the extracts of litchi seeds, Houttuynia cordata, Chinese Rhubarb extracts, Isatis indigotica plants (beta-sistosterol) root extract can inhibit the SARS enzymatic activity 54 .…”

Section: Artificial or Virtual Natural Drug Molecules Screening Methods For Sars-cov-2mentioning

confidence: 99%

An Overview of COVID-19 and the Potential Plant Harboured Secondary Metabolites against SARS-CoV-2: A Review

Swamy¹

2021

J. Pure Appl. Microbiol.

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The SARS-CoV-2 virus causes COVID-19, a pandemic disease, and it is called the novel coronavirus. It belongs to the Coronaviridae family and has been plagued the world since the end of 2019. Viral infection to the lungs causes fluid filling and breathing difficulties, which leads to pneumonia. Pneumonia progresses to ARDS (Acute Respiratory Distress Syndrome), in which fluid fills the air sac and seeps from the pulmonary veins. In the current scenario, several vaccines have been used to control the pandemic worldwide. Even though vaccines are available and their effectiveness is short, it may be helpful to curb the pandemic, but long-term protection is inevitable when we look for other options. Plants have diversified components such as primary and secondary metabolites. These molecules show several activities such as anti-microbial, anti-cancer, anti-helminthic. In addition, these molecules have good binding ability to the SARS-CoV-2 virus proteins such as RdRp (RNA-dependent RNA polymerase), Mpro (Main Protease), etc. Therefore, these herbal molecules could probably be used to control the COVID-19. However, pre-requisite tests, such as cytotoxicity, in vivo, and human experimental studies, are required before plant molecules can be used as potent drugs. Plant metabolites such as alkaloids, isoquinoline ß-carboline, and quinoline alkaloids such as skimmianine, quinine, cinchonine, and dictamine are present in plants and used in a traditional medicinal system.

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Section: Artificial or Virtual Natural Drug Molecules Screening Methods For Sars-cov-2mentioning

confidence: 99%

An Overview of COVID-19 and the Potential Plant Harboured Secondary Metabolites against SARS-CoV-2: A Review

Swamy¹

2021

J. Pure Appl. Microbiol.

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“…Therefore, with all the preventive measures taken into consideration during future Hajj pilgrimage, intensive and regular testing of all intending pilgrims will be a cardinal pointer for a hitch-free and smooth Hajj pilgrimage. It will be imperative for the Hajj and Umrah ministry in Saudi Arabia to employ the latest technology-aided detection and contact-tracing for COVID-19 infection to contain and reduce the spread of the infection [38][39][40][41][42] .…”

Section: Prospect Future Directions and Plansmentioning

confidence: 99%

Hajj Pilgrimage amidst covid-19 pandemic: a review

Goni

Hasan

Deris

et al. 2021

Bangladesh J Med Sci

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Hajj pilgrimage is a nobligation for every Muslim that must be carried out at least once in their lifetime. Every year, more than 3 million pilgrims from over 180 countries travel to worship within a confined area of twelve kilometres in Makkah, Kingdom of Saudi Arabia (KSA). The host country and participating countries need to institute effective measures for a safer and healthier Hajj pilgrimage. In the immediate Hajj season during the COVID-19 pandemic, the number of pilgrims need to be reduced to the optimum number that can be managed individual countries’ Hajj missions. Beside proof COVID-19 clearance before travelling and completed Covid-19 vaccination, the stay in KSA should be shortened for Hajj ritual only. The participating countries responsible to thoroughly select individuals with low risk of severe infections, provide health education program, offer all compulsory and recommended vaccines and allocate adequate healthcare/isolation centres in KSA. The participating countries are also liable to prepare adequate quarantine places for hajj pilgrims when returning home. Individual pilgrims are responsible to prevent respiratory pathogens from spreading. Prior to departure for Hajj, they need to undergo a thorough medical examination, received all compulsory and recommended vaccines and follow health education program. During Hajj, they need to follow instructions by Hajj authorities, practicing proper hygiene, wearing a face mask and avoid crowded places. They also need to report to countries’ Hajj mission healthcare if having any fever or respiratory syndromes. With adequate measures prior, during and post-Hajj, we hope health security risk during the next Hajj seasons will be minimized. Bangladesh Journal of Medical Science Vol.20(4) 2021 p.732-740

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“…However, nurses who are off duty might also get infected so the actual number of nurses who died of this virus might be higher than the official record. Thus, reports of nurses' mortality based on published reports are urgently required to overcome the challenges faced by nurses [5].…”

Section: Introductionmentioning

confidence: 99%

Burnout among nurses working in COVID-19 pandemic

Pujiyanto¹,

Mendrofa

Hani

2022

IJPHS

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Nurses are at high risk of burnout because of the characteristic of their work that expends most of the time in delivering care to the patients. This study aimed to describe burnout among nurses working during corona virus disease 2019 (COVID-19) using nurses' demographic characteristics. This observational cross-sectional study involved 149 nurses from some hospitals and public health centers in Semarang using an online questionnaire from May 1 to June 15, 2020. Primary data were collected using Maslach Burnout Inventory including emotional exhaustion, depersonalization, and reduced personal accomplishment. Univariate and multivariate analyses were performed. The study showed that 63.6% of nurses in the COVID-19 unit were at high levels of emotional exhaustion, 56.3% of them were at high levels of depersonalization, and 46.7% of them are at high levels of reduced personal accomplishment. Education was the only demographic factor that was significantly related to emotional exhaustion and depersonalization (p<0.05) with a weak correlation. The work environment and the reduced anxiety-related factors were not significantly correlated with the reduced personal accomplishment with a very weak correlation, while the nurses’ unit was significantly correlated with depersonalization (p<0.05) with a very weak correlation. The results found that burnout develops among nurses due to the work environment-related factors such as the unit of work, corona-infected patients, personal protective equipment usage, and the specific characteristics of the workplace. Nurses’ characteristics affect their ability to manage the workload even in a pandemic. Nurses need optimal supports to build their self-efficacy. The organizational efforts play an important role in strengthening nurses to prevent burnout.

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Application of Artificial Intelligence-Based Computation in the Health Sciences to Ward off the COVID-19 Pandemic

Cited by 5 publications

References 50 publications

An Overview of COVID-19 and the Potential Plant Harboured Secondary Metabolites against SARS-CoV-2: A Review

An Overview of COVID-19 and the Potential Plant Harboured Secondary Metabolites against SARS-CoV-2: A Review

Hajj Pilgrimage amidst covid-19 pandemic: a review

Burnout among nurses working in COVID-19 pandemic

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