Application of a low power/reduced pressure helium ICP ionization source for mass spectrometric detection of organobromine compounds and derivatized organotin compounds

Waggoner, Joseph W.; Milstein, Lisa; Belkin, Mikhail; Sutton, Karen L.; Caruso, Joseph A.; Fannin, H. B.

doi:10.1039/a905906g

Cited by 25 publications

(20 citation statements)

References 19 publications

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“…GC/ICP MS has first been applied for the analysis of volatile organobromo compounds in environmental samples (Evans & Caruso, 1993; Waggoner et al, 1999; Hardy, 2002; Schwarz & Heumann, 2002; Profrock et al, 2004). Instrumentation has been directed to the design of new GC/plasma interfaces, use of low power plasmas to obtain molecular structural information and the development of more sensitive and robust analytical methodologies.…”

Section: Application Of Mass Spectrometry In the Analysis Of Pbdesmentioning

confidence: 99%

Application of mass spectrometry in the analysis of polybrominated diphenyl ethers

Wang

2009

Mass Spectrometry Reviews

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This review summarized the applications of mass spectrometric techniques for the analysis of the important flame retardants polybrominated diphenyl ethers (PBDEs) to understand the environmental sources, fate and toxicity of PBDEs that were briefly discussed to give a general idea for the need of analytical methodologies. Specific performance of various mass spectrometers hyphenated with, for example, gas chromatograph, liquid chromatograph, and inductively coupled plasma (GC/MS, LC/MS, and ICP/MS, respectively) for the analysis of PBDEs was compared with an objective to present the information on the evolution of MS techniques for determining PBDEs in environmental and human samples. GC/electron capture negative ionization quadrupole MS (GC/NCI qMS), GC/high resolution MS (GC/HRMS) and GC ion trap MS (GC/ITMS) are most commonly used MS techniques for the determination of PBDEs. New analytical technologies such as fast tandem GC/MS and LC/MS become available to improve analyses of higher PBDEs. The development and application of the tandem MS techniques have helped to understand environmental fate and transformations of PBDEs of which abiotic and biotic degradation of decaBDE is thought to be one major source of Br(1-9)BDEs present in the environment in addition to direct loading from commercial mixtures. MS-based proteomics will offer an insight into the molecular mechanisms of toxicity and potential developmental and neurotoxicity of PBDEs.

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Section: Application Of Mass Spectrometry In the Analysis Of Pbdesmentioning

confidence: 99%

Application of mass spectrometry in the analysis of polybrominated diphenyl ethers

Wang

2009

Mass Spectrometry Reviews

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“…One possible solution is the use of one dynamic plasma as an ionization source instead of two 'static' ionization sources [9][10][11][12][13]. A possible dynamic plasma source is the pulsed glow discharge [14,15].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of a pulsed glow discharge time-of-flight mass spectrometer as a detector for gas chromatography and the influence of the glow discharge source parameters on the information volume in chemical speciation analysis

et al. 2006

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The figures of merit of a pulsed glow discharge time-of-flight mass spectrometer (GD-TOFMS) as a detector for gas chromatography (GC) analysis were evaluated. The mass resolution for the GD-TOFMS was determined on FWHM in the high mass range (208Pb+) as high as 5,500. Precision of 400 subsequent analyses was calculated on 63Cu+ to be better than 1% RSD with no significant drift over the time of the analysis. Isotope precision based on the 63Cu+/65Cu+ ratio over 400 analyses was 1.5% RSD. The limits of detection for gaseous analytes (toluene in methanol as solvent) were determined to be as low as several hundred ppb or several hundred pg absolute without using any pre-concentration technique. Furthermore, the different GD source parameters like capillary distance, cathode-anode spacing, and GD source pressure with regards to the accessible elemental, structural, and molecular information were evaluated. It was demonstrated that each of these parameters has severe influence on the ratio of elemental, structural, and parent molecular information in chemical speciation analysis.

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“…Caruso et al [192,193] have also used GC-LP-ICPMS to obtain elemental and structural information from chromatographic eluents. Limits of detection at the pg level were obtained for organobromine compounds when helium was used as the plasma gas [193].…”

Section: Reduced-pressure Plasmas As Tunable Ion Sourcesmentioning

confidence: 99%

“…Limits of detection at the pg level were obtained for organobromine compounds when helium was used as the plasma gas [193]. In addition, the authors demonstrated the capability of the system to produce tunable fragmentation of organotin compounds by varying the helium/argon plasmagas ratio [192].…”

Section: Reduced-pressure Plasmas As Tunable Ion Sourcesmentioning

confidence: 99%

Plasma-source mass spectrometry for speciation analysis: state-of-the-art

Ray¹,

Andrade²,

Gamez³

et al. 2004

Journal of Chromatography A

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Current and emerging capabilities of plasma-source mass spectrometry (PS-MS) as it is employed for elemental speciation analysis are reviewed. Fundamental concepts and their advantageous aspects, experimental conditions, and analytical performance are described and illustrated by recent examples from the literature. Novel instrumentation, techniques, and strategies for inductively-coupled plasma mass spectrometry (ICP-MS), microwave-induced plasma (MIP) mass spectrometry, glow-discharge (GD) mass spectrometry, and electrospray ionization (ESI), among others, are described. The use of ionization sources that provide tunable ionization, others that can be modulated between different sets of operating conditions, and others used in parallel is also examined.

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Application of a low power/reduced pressure helium ICP ionization source for mass spectrometric detection of organobromine compounds and derivatized organotin compounds

Cited by 25 publications

References 19 publications

Application of mass spectrometry in the analysis of polybrominated diphenyl ethers

Application of mass spectrometry in the analysis of polybrominated diphenyl ethers

Evaluation of a pulsed glow discharge time-of-flight mass spectrometer as a detector for gas chromatography and the influence of the glow discharge source parameters on the information volume in chemical speciation analysis

Plasma-source mass spectrometry for speciation analysis: state-of-the-art

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