[Purpose] The purpose of the present study was to determine the effect of a jump rope and
ball combined exercise program on the physical fitness the neurotransmitter (epinephrine,
serotonin) levels of children with attention-deficit hyperactivity disorder. [Subjects and
Methods] The subjects were 12 boys attending elementary school, whose grade levels ranged
from 1–4. The block randomization method was used to distribute the participants between
the combined exercise group (n = 6) and control group (n = 6). The program consisted of a
60-min exercise (10-min warm-up, 40-min main exercise, and 10-min cool down) performed
three times a week, for a total of 12 weeks. [Results] The exercise group showed a
significant improvement in cardiorespiratory endurance, muscle strength, muscle endurance
and flexibility after 12 weeks. A significant increase in the epinephrine level was
observed in the exercise group. [Conclusion] The 12-week combined exercise program in the
current study (jump rope and ball exercises) had a positive effect on overall fitness
level, and neurotransmission in children with attention-deficit hyperactivity
disorder.