Appendicitis: Evaluation by TC-99m leukocyte scan

Henneman, Philip L.; Marcus, Carol S.; Butler, John; Freedland, Eric S.; Wilson, Samuel E.; Rothstein, Robert J.

doi:10.1016/s0196-0644(88)80292-0

Cited by 22 publications

(5 citation statements)

References 19 publications

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“…About 240 studies presented original data relating to the clinical diagnosis of appendicitis. Fifty‐four studies of the diagnosis of appendicitis in patients admitted for suspected appendicitis were identified; 30 of these were not selected for analysis because they included only children11–22, the results were presented in a way that did not permit extraction of data for analysis16, 23–32, the presented results were inconsistent33, 34, patients with other diagnoses found at exploration (but not requiring surgical treatment) were included among those with appendicitis35, non‐consecutive patients were selected at convenience36, 37 or unusual variables were included that were not analysed by any other study (caecal squelch, continuous tenderness on prolonged pressure over McBurney's point and the value of repeat examination)38–40.…”

Section: Methodsmentioning

confidence: 99%

Meta-analysis of the clinical and laboratory diagnosis of appendicitis

Andersson

2003

British Journal of Surgery

499

374

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Section: Methodsmentioning

confidence: 99%

Meta-analysis of the clinical and laboratory diagnosis of appendicitis

Andersson

2003

British Journal of Surgery

499

374

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“…Barium enema examination is not obsolete, however, and may be useful in evaluating complex colonic abnormalities detected with cross-sectional imaging (51). While investigators have explored the potential of magnetic resonance imaging (97) and radioactive isotope imaging (98,99) in patients with acute appendicitis, there is no current practical role for these imaging modalities in this patient population.…”

Section: Us Versus Ctmentioning

confidence: 99%

Appendicitis at the Millennium

Birnbaum¹,

Wilson²

2000

Radiology

526

430

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Acute appendicitis is a common clinical problem. Accurate and prompt diagnosis is essential to minimize morbidity. While the clinical diagnosis may be straightforward in patients who present with classic signs and symptoms, atypical presentations may result in diagnostic confusion and delay in treatment. Helical computed tomography (CT) and graded compression color Doppler ultrasonography (US) are highly accurate means of establishing the diagnosis. These imaging modalities have now assumed critical roles in the treatment of patients suspected to have appendicitis. The purpose of this article is threefold: to provide an update on new information regarding the pathophysiology, clinical diagnosis, and laparoscopic treatment of acute appendicitis; to describe the state-of-the art use of CT and US in diagnosing this disease entity; and to address the role of medical imaging in this patient population.

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“…Immunoglobulin G antibody scans may offer more promise, but only the results of preliminary trials have been reported (198,199). Other scintigraphic modalities have been studied, but they have been limited by prolonged preparation times, inferior sensitivity and/or specificity, high frequencies of uninterpretable images or high cost of the radionuclide (200)(201)(202)(203).…”

Section: Nuclear Imagingmentioning

confidence: 99%

The Role of Radiological Imaging in the Diagnosis of Acute Appendicitis

Albiston¹

2002

Canadian Journal of Gastroenterology

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Several strategies have been employed to improve the accuracy of the diagnosis of appendicitis and to reduce the associated perforation rate. Because clinical algorithms have been disappointing, many physicians resort to radiological modalities. Plain abdominal x-rays are nonspecific, barium enema examination has relatively low accuracy, scintigraphy scans require considerable time and are difficult to interpret, and magnetic resonance imaging is relatively unstudied. The most promising modalities are graded compression sonography and computed tomography. In expert hands, these techniques can achieve a high degree of accuracy. Nevertheless, most published studies have been marred by methodological difficulties. Moreover, ultrasound is more useful in detecting than in ruling out appendicitis. The radiological criteria for acute appendicitis, the accuracy of various imaging modalities and the limitations of the available research are described.

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Appendicitis: Evaluation by TC-99m leukocyte scan

Cited by 22 publications

References 19 publications

Meta-analysis of the clinical and laboratory diagnosis of appendicitis

Meta-analysis of the clinical and laboratory diagnosis of appendicitis

Appendicitis at the Millennium

The Role of Radiological Imaging in the Diagnosis of Acute Appendicitis

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