Appendiceal Mucinous Cystadenoma

Honnef, Ingo; Moschopulos, Michael; Roeren, T

doi:10.1148/rg.285075160

Cited by 28 publications

(46 citation statements)

References 10 publications

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“…Laparoscopic appendectomy for benign mucinous tumour removal has been described (traditional and single incision [13,14]), but caution has also been suggested because of the risk of tumour seeding. It is probably safer to convert to an open procedure if AMT is visualized during a laparoscopic approach [2,3,13,14]. All except one of the operations performed in our series were open.…”

Section: Discussionmentioning

confidence: 84%

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Long-Term Outcomes after Surgery for Appendiceal Mucinous Tumours

Dulskas

Poškus

et al. 2017

Visc Med

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Background: Appendiceal mucinous tumour (AMT) is a very uncommon disease. We aimed to evaluate preoperative and postoperative characteristics as well as long-term outcomes of patients with appendiceal mucinous adenomas and peritoneal pseudomyxoma (PMP). Methods: A consecutive cohort of patients diagnosed with AMT were included in the study. Tumour recurrence and the development of PMP was diagnosed based on the patients' complaints, physical examination, imaging studies, and biopsy results. The calculation of survival rates was performed using the Kaplan-Meier method. Results: Between January 2003 and February 2013, 25 patients had AMT. 15 patients underwent appendectomy only (60%), 5 patients (20%) right hemicolectomy, 4 patients (16%) cytoreductive surgery (CRS) ± hyperthermic intraperitoneal chemotherapy (HIPEC), and 1 patient (4%) appendectomy with caecal resection. Another 2 patients underwent CRS and HIPEC 4 days and 3 years, respectively, following initial appendectomy. In the histopathologic examination, adenoma was diagnosed in 12 patients (48%); among these, low-grade PMP was found in 1 patient (4%). Low-grade appendiceal mucinous adenocarcinoma (AMCa) was diagnosed in 11 patients (44%); among these, low-grade PMP was found in seven cases (28%) and high-grade AMCa was diagnosed in 2 patients (8%). 2 of 8 PMP patients did not undergo CRS ± HIPEC because of comorbidities. The 5-year overall survival was 100% for the adenomas and 62% for PMP patients. Conclusion: AMT is a very rare entity with a considerably good outcome even in disseminated disease. CRS and HIPEC is a gold standard treatment for PMP with excellent prognosis. However, our results could still be improved in the future.

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Section: Discussionmentioning

confidence: 84%

“…Mucocele is a rare pathology of the appendix ranging between 0.2 and 0.7% of all appendectomies [2][3][4]. Classification and management of AMT is very problematic for both clinicians and pathologists.…”

Section: Introductionmentioning

confidence: 99%

Long-Term Outcomes after Surgery for Appendiceal Mucinous Tumours

Dulskas

Poškus

et al. 2017

Visc Med

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“…In addition, it exhibited a signal intensity lower than that of the skeletal In the present case, the large tumor of the thigh was interlinked with the pelvic cavity. It is important to observe the association between the lesion and pelvic organs, such as the appendix or ovaries, as appendiceal mucinous neoplasm may invade organizations outside of the mucous layer of the appendix and cause secondary peritoneal myxoma (10). Inside the mucus, epithelial cells rich in secretory functions can be found (11).…”

Section: Discussionmentioning

confidence: 99%

Myxoma of the upper leg originating from an appendiceal mucinous neoplasm: A case report

Zhang

Wang

et al. 2015

Oncology Letters

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Abstract. Myxoma is rare in the upper leg. The current study presents the case of a large tumor in the right upper leg. The tumor extended to pelvic cavity and was found to be connected with a cystic and solid neoplasm that was adjacent to the ascending colon in the right lower quadrant. The large tumor of the upper leg had existed for 15 years and had ulcerated through the skin 4 days prior to admittance. Palliative surgery was performed, with histological findings of a myxoma. Since appendiceal mucinous neoplasms may invade organizations outside of the mucous layer of the appendix and cause secondary peritoneal myxoma, this myxoma of the upper leg probably originated from an appendiceal mucinous neoplasm. IntroductionMyxomas are benign neoplasms that are characterized by slow growth (1). The most frequent location of those neoplasms is the cardiac muscle, where they account for 50% of all benign lesions (2). Myxoma is rare in the leg, but can occur within its muscles (1). To date, <10 cases of myxoma located in the leg have been documented (1,(3)(4)(5). Computed tomography usually shows a well-delimited mass with an absorption density between that of muscle and water. The most precise examination technique that enables diagnosis is magnetic resonance (MR) imaging (6,7), and radical removal of the whole lesion is the most effective method of treating myxomas (8). The present study reports a case of myxoma localized to the leg and interlinked with the pelvic cavity, which was treated with palliative surgery. To the best of our knowledge, this study is the first to describe the possibility of a leg myxoma originating from an appendiceal mucinous neoplasm. Case reportAn 88-year-old female was hospitalized at Yantai Affiliated Hospital of Binzhou Medical University (Yantai, China) in January 2014 with a large tumor in the right upper leg. The tumor had existed for 15 years and had ulcerated through the skin 4 days prior to admittance. The function and appearance of the right lower limb were seriously affected. Laboratory examinations showed no abnormalities and no other symptoms were observed. The MR studies were performed by a SIEMENS Avanto 1.5T MR scanner. A large tumor (45x15x20 cm) in the right thigh was found with a slight high signal on T1-weighted imaging (Fig. 1A) and an appreciable high signal on T2-weighted imaging (Fig. 1B). The tumor extended to the pelvic cavity and was found to be connected with a cystic and solid neoplasm (Fig. 1C). Due to the older age of the patient, total resection was considered to be too traumatic. Instead, the patient underwent palliative surgery for the tumor in the upper leg, and the tumor was found to be full of brown and yellow gelatinous material. Myxoma was finally diagnosed via histological examination (Fig. 2). Following surgery, the patient recovered well and was subsequently discharged. The patient rejected further treatment and no follow-up examination was planned. At the time of writing, the patient was alive.This study was approved by the Ethics Committee of Binzh...

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“…Las tumoraciones del apéndice son patologías poco frecuentes, su diagnóstico prequirúrgico es difícil por lo que la mayoría de estas patologías se intervienen con diagnóstico de apendicitis aguda y se encuentran como hallazgo incidental, dicha presentación caracterizada por la paciente presentada en este caso clínico [4][5][6] . El tratamiento es quirúrgico pudiendo ser suficiente la apendicectomía sola en patologías benignas, o bien, tratamientos más invasivos como la hemicolectomía derecha y quimioterapia 7,8 en sospecha de patologías malignas; siendo la resección intestinal e ileostomía el tratamiento sugerido para nuestro caso sin tener evidencia de histopatológico causal, dadas las condiciones de presentación de nuestro caso y la gangrena evidenciada [9][10][11][12] . La literatura refiere un predominio del sexo femenino, tal y como ocurre con nuestra paciente y una edad entre la quinta y sexta década en promedio 13 en diversas comunicaciones hay discordancia en estos datos 14,15 .…”

Section: Discussionunclassified

“…Ultrasonido: que muestra una lesión encapsulada quística y en ocasiones se observa el "signo de la piel de cebolla" el cual consiste en muchas capas ecogénicas a lo largo de un apéndice dilatado 18 . Tomografía: con alta sensibilidad para la detección de los adenomas mucinosos (AM) 19 en que se observa una imagen homogénea y quística bien delimitada, con áreas centrales de atenuación y contenido con densidad similar al agua 20 . En el 50% de los casos hay calcificaciones en la pared apendicular, muy sugestiva de mucocele 21 .…”

Section: Discussionunclassified

Cistadenoma mucinoso del apéndice cecal como causa de gangrena intestinal

M¹,

S²,

C³

2013

Rev Chil Cir

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Appendiceal mucocele causing large bowel gangrene Introduction: Appendiceal mucocele are lesions located in the cecum, which are found in 0.2 to 0.3% of appendectomies and correspond to 8-10% of all appendiceal tumors. Clinical case: We report a 83 years old female consulting for abdominal pain lasting 24 hours. On physical examination, signs of peritoneal irritation were found. The patient was operated, finding an appendiceal tumor that was coiled up in the mesentery with large bowel gangrene. An intestinal resection, terminal ileostomy, appendectomy and surgical lavage were performed. The pathological study of the surgical piece reported a mucinous cystadenoma.

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Appendiceal Mucinous Cystadenoma

Cited by 28 publications

References 10 publications

Long-Term Outcomes after Surgery for Appendiceal Mucinous Tumours

Long-Term Outcomes after Surgery for Appendiceal Mucinous Tumours

Myxoma of the upper leg originating from an appendiceal mucinous neoplasm: A case report

Cistadenoma mucinoso del apéndice cecal como causa de gangrena intestinal

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