Appendectomy is more frequent but not a risk factor in Crohn's disease while being protective in ulcerative colitis: a comparison of surgical procedures in inflammatory bowel disease

Abstract

Appendectomy is protective in UC; it is more frequent, but not a risk factor in CD. The role of cholecystectomy should be investigated further.

Population‐based cases control study of inflammatory bowel disease risk factors

“…Tonsillectomy was more common in CD cases than controls, consistent with some, but not all studies. 6,7,9 Previous appendicectomy is protective for the development of UC, in agreement with other studies, 8,9 and was associated with later development of CD (probably confounded by the misdiagnosis of CD as appendicitis, leading to appendicectomy 8,9 ).…”

Tonsillectomy and the risk of inflammatory bowel disease: A systematic review and meta‐analysis

“…Finally, 23 observational studies were included in our meta-analysis. [7][8][9][10][11][12][13][14][15][16][17][18][19][20][25][26][27][28][29][30][31][32][33] Of these, 22 studies explored the relationship between tonsillectomy and UC, [7][8][9][10][11][12][13][14][15][16][17][18]20,[25][26][27][28][29][30][31][32][33] and 17 investigated the relationship of tonsillectomy with CD. 7,[9][10][11][12][13]…”

“…Tonsillectomy and Crohn's disease. There were 17 studies [9][10][11][12][13][14][15][16][17]19,26,27,[29][30][31][32] involving a total of 7666 CD patients and 754 067 controls that reported on the prevalence of tonsillectomy in the two groups. When all the studies that offered CD-specific data were brought into the analysis, the pooled OR of developing CD Tonsillectomy and risk of IBD W Sun et al…”

“…Several studies demonstrated a significantly negative correlation between tonsillectomy and UC, 13 but this pronounced association cannot be reproduced in many other studies. 9,10,12,[14][15][16][17][18] Conversely, a positive association between tonsillectomy and CD has described in some reports, 12,15,19 while results with no significant relationship have also been reported in many other studies. 10,16,17,20 Taking the indeterminate results into account, we have carried out this meta-analysis in order to reach a more definite conclusion, by comprehensive evaluation of the effect of tonsillectomy on the development of IBD.…”

Tonsillectomy and inflammatory bowel disease: a meta‐analysis

“…Reif et al . interviewed 271 patients with UC, 260 with CD, 475 clinic controls and 428 community controls. Koutroubakis et al .…”