Apparatus and method for clinical recorded of the electroretinogram

Karpe, G.

doi:10.1007/bf00204534

Cited by 51 publications

(25 citation statements)

References 5 publications

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“…The electroretinogram was investigated with the apparatus and the method described by Karpe (1948 a ) . All the cases were examined with a standard light stimulus of 20 m. c.…”

Section: Methodmentioning

confidence: 99%

The Clinical Electroretinogram

Vainio-Mattila

1951

Acta Ophthalmologica

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It is essential to know all the details of the normal electroretinogram (ERG) when using electroretinography for clinical purposes. The investigations made hitherto on the normal ERG in man, however, have not been aimed at determining whether there is any difference dependent on sex.Karpe's normal material (1945) consisted of 74 eyes in 48 patients between the ages of 11 and 50 years of which 37 were young men between 21 and 35 years. Only six of the cases, however, were women. The mean b-potential for these women's eyes was 0.40 mV as compared with 0.36 mV for all the eyes in the series. Another normal material of patients above 50 years of age assembled by Karpe, Rickenbach and Tllomasson (1950) comprised 33 eyes in 19 men and 41 eyes in 21 women. Here, too, the mean b-potential differed between the men and the women as follows: men 0.30 k 0.066 m V * * ) ; women 0.34 f 0.080* * ) mV. The difference between these bpotential values is ,0.04 f 0.016* * * ) and is therefore probably significant.Both these investigations thus suggest that there is normal-*) Received Nov. 6th 1950. *') standard deviation o = I/ 2 (Pi M)2

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“…The electroretinogram was investigated with the apparatus and the method described by Karpe (1948 a ) . All the cases were examined with a standard light stimulus of 20 m. c.…”

Section: Methodmentioning

confidence: 99%

The Clinical Electroretinogram

Vainio-Mattila

1951

Acta Ophthalmologica

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“…As the b-wave of the ERG has its origin mainly in the inner nuclear layer [Arden and Brown, 1965] electroretinography becomes a very fine indicator for early siderotic changes in the retina. In fact, electroretinography has been introduced into clinical use for early detection of siderosis of the eye as far back as 1945 by Karpe [1948a]. In the meantime many investigations on the ERG have been performed to find out more about siderosis of the eye.…”

Section: Introductionmentioning

confidence: 99%

Experimental Siderosis of the Isolated Retina Induced by Fe(III) Solutions

Dahl¹,

Borchard²

1975

Ophthalmic Res

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The effect of Fe(III) ions in the range from 3 to 100 μmol/l on the electroretinogram (ERG) of the isolated frog retina was investigated. The perfusion with the test solution containing iron lasted 45 min. After moist combustion of the tissue the iron content of the retinae was determined by photometry using bathophenanthroline as an indicator. The ERG changes during experimental siderosis showed some analogy to clinical ERG classification of siderosis of the eye. Low Fe(III) concentrations of the test solution (3 μmol/l) had no significant effect on the ERG. At 10 μmol/l a decrease of the ERG could be observed which was less pronounced at 18 and 24 μmol/l. At 30 μmol/l Fe(III) and even higher concentrations there was a rapid and irreversible drop in potential. Increasing Fe(III) concentration of the bathing solution brought about an accumulation of iron in the retina which could not be eluted by desferrioxamine B (DF). This agrees with the observation that DF did not improve the ERG after intoxication with 100 μmol/l Fe(III).

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“…Jacobson (1955), however, stated that much of the difficulty in performing routine electroretinography lay in the contact lens electrode and especially when the Karpe (1948)speculum was used. With Jacobson's modified electrode, 300 ERGs were performed without difficulty; but examination of the cornea by slit lamp using cobalt blue filter was not cited in the Jacobson or the other above-noted series.…”

Section: Discussionmentioning

confidence: 99%

“…Essentially five contact lens electrode models are in use: 1. Those utilizing isotonic saline and methylceUulose in the dome or cup (Karpe, 1948;Henkes, 1951;Jacobson, 1955); 2. The Bufian-Allen speculum-type employing methylcellulose (Burian and Allen, 1954); 3.…”

Section: Introductionmentioning

confidence: 99%

Electroretinographic testing in diabetics a comparison study of the burian-allen and the henkes corneal electrodes

1980

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A series of 57 diabetics underwent standard electroretinographic recordings for the purpose of testing the effect of insulin on the electroretinograms in diabetes mellitus, specifically on the oscillatory potential changes (Kozak et al., Jap. J. Ophthal. Suppl., 1979). Use of the speculum-type corneal electrode (Burian-Allen, Hansen Labs.,) produced 9 corneal abrasions in the first 28 patients in this series. However, when the technique of examination was altered by use of the Henkes-type bipolar electrode, only 2 abrasions were produced in the last 29 patients. These frequencies of abrasions are statistically different. The suggestion is made that electroretinographic tracings in diabetics the performed with the use of the Henkes bipolar low-vacuum corneal electrode (Medical Workshops, Holland).

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Apparatus and method for clinical recorded of the electroretinogram

Cited by 51 publications

References 5 publications

The Clinical Electroretinogram

The Clinical Electroretinogram

Experimental Siderosis of the Isolated Retina Induced by Fe(III) Solutions

Electroretinographic testing in diabetics a comparison study of the burian-allen and the henkes corneal electrodes

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