Aplasia of the Optic Nerve*

Electroretinographical Study of the Hypoplasia of the Optic Nerve

“…Hypoplasia of the optic nerve has not only been described in human beings, but also in horses [Gelatt et al, 1969], cattle [Leipold and H uston, 1968], dogs [Saunders, 1952;G elatt and Leipold, 1971] and mice [Bein, 1947], Unilateral cases of hypoplasia of the optic nerve have been described by E verbusch [1885], Cords [1923], Velhagen [1930], A ppelmans and W ibo [1939], Smith [1954; 2 cases], Walsh [1957], Somerville [1962], Nagy [1962], Sobanska-Gotz [1963] [1959], Kytila and M iettinen [1961; 2 brothers], Sobanska-G otz [1963], E dwards and Layden [1970], E llenberger and R unyan [1970], Gardner and Irvine [1972], Layman et al [1974; 9 cases associated with aniridia].…”

“…The retina surrounding the optic disc is either normal, or slightly dystrophic with a marked choroidal pattern [Ridley, 1938;Smith, 1954J. Absence of the foveal reflex or an abnormal appearance of the macula has been reported [Everbusch, 1885;Duane, 1905;Schwarz, 1915;Scheie and A dler, 1941;Smith, 1954;Kytila and M iettinen, 1961;Layman et al, 1974].…”

Okulo-zerebrale Dysplasie: Aplasia nervi optici sowie familiärer Mikr- und Kryptophthalmus

“…Abb. (Ridley, 1938, Scheie und Adler, 1941, Smith, 1954, Kytilaund Miettinen, 1961, Somerville, 1962. Little fand bis 1976 nur sechs echte Aplasien in der Literatur, Weiter und Mitarb.…”