Aortic body tumours in a Boxer dog with a review of the literature

Richards, M. A.; Mawdesley-Thomas, Lionel E.

doi:10.1002/path.1710980408

Cited by 16 publications

(8 citation statements)

References 13 publications

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“…In 22 per cent of the dogs there was distant metastasis, and metastasis was more common in dogs with carotid body paragangliomas than in those with aortic body neoplasms. These findings differ from those of other investigators who report metastasis to be uncommon (Richards & Mawdesley-Thomas, 1969) or under 22 per cent (Johnson, 1968;Hayes & Fraumeni, 1974;Dean & Strafuss, 1975). In man, the rate of metastasis varies according to the sites of origin (Staats, Brown & Smith, 1966;Rangwala, Sylvia & Becker, 1978;Lack, Cubilla & Woodruff, 1979).…”

Section: Introductioncontrasting

confidence: 93%

“…The histologic features (Richards & Mawdesley-Thomas, 1969;Glenner & Grimley, 1974;Patnaik, Lord & Liu, 1974;Dean & Strafuss, 1975;Patnaik et a/., 1975;Van Nes et al, 1978) and ultrastructural (Grimley & Glenner, 1967;Cheville, 1972;Alpert & Bochetto, 1974;Glenner & Grimley, 1974;Robertson & Cooney, 1980) features of paragangliomas at different sites in man and the dog have been described. Roentgenographic aspects of human head and neck chemodectomas have also been described (Palacios, 1970).…”

Section: Introductionmentioning

confidence: 99%

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Canine paraganglioma: a case report

Patnaik

Birchard

1985

J of Small Animal Practice

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An 8‐year‐old castrated Cocker Spaniel with tympanic paraganglioma was presented. The tumour was resected twice with an interval of 120 days. The dog presented with tetraparesis 130 days after the second operation and had radiologic evidence of metastasis to the C5 vertebra. On pathologic examination, metastasis of the tumour was found in the myocardium, lungs, kidney, and C5 vertebra. The tumour, which is being described for the first time in the dog, was highly vascular, and was characterized by various‐sized groups of medium‐sized cells separated by vascular stroma. The neoplastic cells were round or polyhedral with moderately hyperchromatic nuclei, scattered chromatin, indistinct nucleoli, and eosinophilic granular cytoplasm. The metastatic lesions were histologically similar to the primary tumour.

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Section: Introductioncontrasting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Canine paraganglioma: a case report

Patnaik

Birchard

1985

J of Small Animal Practice

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“…The majority of canine ABT reported in the literature have been in brachycephalic breeds, specifically Boxers and Boston Terriers. 22,23,31,34,37,42,47,57,63,64,[67][68][69] In 1 study, a nonsignificant trend was identified toward increased risk of ABT in English bulldogs 22 , an ancestral breed of Boxers and Boston Terriers. The present study determined these breeds to have a higher occurrence of all cardiac tumors evaluated together.…”

Section: Discussionmentioning

confidence: 99%

“…2,4,8,33 Aortic body tumors (ABT) also have been reported relatively frequently in dogs. 7,22,25,31,32,34,37,42,43,45,47,49,57,[62][63][64][65][66][67][68][69] ABT are tumors of chemoreceptor tissue located at the aortic root or heart base. Only sporadic cases of cardiac myxoma have been reported in dogs.…”

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confidence: 99%

Cardiac Tumors in Dogs: 1982–1995

Ware

Hopper

1999

Veterinary Internal Medicne

205

185

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A Veterinary Medical Database search from 1982 to 1995 identified 1,383 dogs with tumors of the heart from a total population of 729,265 dogs (0.19% incidence). Hemangiosarcoma (HSA) was the most common cardiac tumor identified. In the subset of dogs with specific histologic diagnoses, the number with HSA was almost 10-fold that of the 2nd most common tumor, aortic body tumor. Primary heart tumors were more common than cardiac metastases. When biologic behavior was noted, most heart tumors were classified as malignant. Cardiac tumors (excluding lymphoma) occurred most often in dogs between the ages of 7 and 15 years. In very old dogs (>15 years), the frequency of cardiac tumors was the same or lower than that of the youngest age group. Tumors occurred with similar frequency in males and females, but the relative risk for spayed females was >4 times that for intact females. For HSA, spayed females had >5 times greater relative risk than did intact females. The risk for castrated males was slightly greater than that for intact males, which had 2.4 times the relative risk of intact females. Thus, neutering appeared to increase the risk of cardiac tumor in both sexes. Intact females were least likely to develop a cardiac tumor, whereas spayed females were most likely to develop a tumor. Twelve breeds had greater than average risk of developing a cardiac tumor, whereas 17 had lower risk.

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“…Aortic body tumours are encountered more frequently than neoplasms of carotid body in animals however, the reverse is true for humans (Capen 1985). In the dog, metastasis of aortic body tumours to the regional lymph nodes, lungs, liver and other organs has been reported (Riser and Bailey 1949, Nilsson 1955, 1956, Yates and others 1980, although local infiltration and expansion without metastasis is more common (Richards and Mawdesley-Thomas 1969). Secondary aortic body tumours in bone are rare and have only been reported by Szczech and others (1973) in the lumbar vertebrae and Carlisle and others (1978) in the thoracic vertebrae.…”

Section: Introductionmentioning

confidence: 98%